Results 121 to 130 of about 3,446,178 (280)

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Trunk Inclination Estimate During the Sprint Start Using an Inertial Measurement Unit: A Validation Study [PDF]

, 2013
The proper execution of the sprint start is crucial in determining the performance during a sprint race. In this respect, when moving from the crouch to the upright position, trunk kinematics is a key element.
GUILLON, Pélagie, CAPPOZZO, Aurelio, CAMOMILLA, Valentina, SKALLI, Wafa, PILLET, Helene, BERGAMINI, Elena   +5 more
core   +1 more source

The effect of pre‐exercise hyperventilation on repeated high‐intensity inclined sprint performance

Experimental Physiology
High‐intensity exercise induces systemic acidosis, which contributes to muscular performance decline. Controlled pre‐exercise hyperventilation has been proposed as a non‐invasive intervention to induce respiratory alkalosis and counteract acidosis ...
Leon Fesseler, Andreas Patzak, Viktor Heinz, Ngan‐Ha Stella Le, Oliver Opatz, Niklas Pilz, Tomas Lucca Bothe   +6 more
doaj   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

Advanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou, Inês Afonso Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara‐Camelia Rusu, Aylin Nebol, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti   +12 more
wiley   +1 more source

Effects of Short Sprint Interval Training and Long Sprint Interval Training on Alactic and Lactic Anaerobic Capacities [PDF]

This research the aims tis to examine the influence of short sprint interval training (SPI) and long sprint interval training (LPI) on anaerobic capacity of Alactase (AA) and Lactase (LA). The subjects were 29 Junior Secondary students Makassar random ly
Irmawati, Irmawati, Syahruddin, Syahruddin_, Saleh, M. Sahib, Saleh, Muhammad Syahrul   +3 more
core  

The Effects of an Eight-Week Small-Sided Game-Based High-Intensity Interval Training Intervention and Traditional High-Intensity Interval Training Intervention on Physical Fitness in Youth Female Soccer Players

Physical Education Theory and Methodology
Objectives. The study aimed to compare the outcomes of an eight-week Small-Sided Game-based High-Intensity Interval Training (SSG-HIIT) and Traditional High-Intensity Interval Training (THIIT) on parameters of physical fitness in youth female soccer ...
Bharat Prasad, Sohom Saha, Sukanta Das, Erianti, Ritik Kumar Singh, Mark Anthony Dalpie, Simran Obhrai, Prabir Mondal   +7 more
doaj   +1 more source

Tunable Negative Thermal Expansion in Fe/Cr‐Substituted Nd2Co17 Compounds via Magnetoelastic Coupling

Advanced Science, EarlyView.
This study achieves anisotropic thermal expansion tuning in Nd2(Co1‐xFex)17‐yCry compounds via a magnetoelastic strategy. Variable‐temperature synchrotron X‐ray diffraction reveals that increased Fe content induces switchable lattice responses. Compositional control reduces the volume expansion coefficient αV by 20% (x═0.7) and modulates TC (442–625 K),
Jiayuan Li, Chenfei Qv, Haoran Tu, Qinfen Gu, Wayne D. Hutchison, Stewart J. Campbell, Zhenxiang Cheng, Wenquan Wang, Jianli Wang   +8 more
wiley   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source