Results 191 to 200 of about 512,141 (378)
Metal‐Mediated Protein Engineering within Live Cells
Chemistry – An Asian Journal, Volume 20, Issue 6, March 17, 2025.This review discusses how metal ions can mediate protein modification within live cells. With its easy handling, rapid solubility, and ease of internalization within the cells, metal ions can be an excellent stimulus for many organic reactions needed within an intracellular medium, which can modify proteins and lead to applications in chemistry ...
Pritam Ghosh
wiley +1 more source
Autism Research, EarlyView.ABSTRACT Clinical language assessments often influence the types of services that autistic children are eligible to receive. However, these assessments often take place outside of the child's natural language environment. In this study, we assess the potential of using naturalistic language processing technology, the Language ENvironment Analysis (LENA)
Nicole Nadwodny +14 more
wiley +1 more source
Therapeutic reasoning in case reports: Insights into current reporting and learning opportunities
British Journal of Clinical Pharmacology, EarlyView.Aims While case reports can help to train diagnostic reasoning, will they improve therapeutic reasoning as well? Prescribing the right medication is difficult and prone to error, which can lead to patient harm. Therefore, good therapeutic reasoning skills are essential.
Mariëlle G. Hartjes +5 more
wiley +1 more source
The stability of simulation based estimation of the multiperiod multinominal probit model with individual specific covariates [PDF]
The multi-period multinomial Probit model (MMPM) is seen as a flexible tool to explain individual choices among several alternatives over time. There are two versions of this model: a) for each individual the covariates for all alternatives are known and
Kaltenborn, Ulrich, Rendtel, Ulrich
core
BMEMat, EarlyView.This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan +12 more
wiley +1 more source
Cancer Communications, EarlyView.Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li +23 more
wiley +1 more source
Targeting MAN1B1 potently enhances bladder cancer antitumor immunity via deglycosylation of CD47
Cancer Communications, EarlyView.Abstract Background Only a few bladder cancer patients benefit from anti‐programmed cell death protein 1/programmed cell death ligand 1 immunotherapy. The cluster of differentiation 47 (CD47) plays an important role in tumor immune evasion. CD47 is a highly glycosylated protein, however, the mechanisms governing CD47 glycosylation and its potential ...
Jie Zhang +20 more
wiley +1 more source