Results 11 to 20 of about 12,750 (218)

Sex and age differences in sST2 in cardiovascular disease

Frontiers in Cardiovascular Medicine, 2023
AimsThe goal of this study was to determine whether sex and age differences exist for soluble ST2 (sST2) for several cardiovascular diseases (CVDs).MethodsWe examined sST2 levels using an ELISA kit for myocarditis (n = 303), cardiomyopathy (n = 293 ...
Danielle J. Beetler, Danielle J. Beetler, Danielle J. Beetler, Katelyn A. Bruno, Katelyn A. Bruno, Damian N. Di Florio, Damian N. Di Florio, Damian N. Di Florio, Erika J. Douglass, Swikriti Shrestha, Swikriti Shrestha, Swikriti Shrestha, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Madeleine W. Cunningham, Jan Krejčí, Jan Krejčí, Julie Bienertová-Vašků, Julie Bienertová-Vašků, Sabine Pankuweit, Dennis M. McNamara, Dennis M. McNamara, Eun-Seok Jeon, Sophie van Linthout, Sophie van Linthout, Lori A. Blauwet, Leslie T. Cooper, DeLisa Fairweather, DeLisa Fairweather, DeLisa Fairweather   +30 more
doaj   +3 more sources

sST2 and Heart Failure—Clinical Utility and Prognosis

Journal of Clinical Medicine, 2023
New parameters and markers are constantly being sought to help better assess patients with heart failure (HF). ST2 protein has gained interest as a potential biomarker in cardiovascular disease. It is known that the IL-33/ST2L system belongs to the cardioprotective pathway, which prevents the fibrosis, hypertrophy, and apoptosis of cardiomyocytes and ...
Magdalena Dudek, Marta Kałużna-Oleksy, Jacek Migaj, Filip Sawczak, Helena Krysztofiak, Maciej Lesiak, Ewa Straburzyńska-Migaj   +6 more
openaire   +3 more sources

Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? [PDF]

PLoS ONE, 2012
Preliminary data mostly from animal models suggest the sST2/IL-33 pathway may have causal relevance for vascular disease and diabetes and thus point to a potential novel inflammatory link to cardiometabolic disease.
Ashley M Miller, David Purves, Alex McConnachie, Darren L Asquith, G David Batty, Harry Burns, Jonathan Cavanagh, Ian Ford, Jennifer S McLean, Chris J Packard, Paul G Shiels, Helen Turner, Yoga N Velupillai, Kevin A Deans, Paul Welsh, Iain B McInnes, Naveed Sattar   +16 more
doaj   +1 more source

Prognostic Value of sST2 in Heart Failure

Journal of Clinical Medicine, 2023
In recent years, there has been growing interest in the risk stratification for heart failure, and the use of multiple biomarkers to identify different pathophysiological processes associated with this condition. One such biomarker is soluble suppression of tumorigenicity-2 (sST2), which has shown some potential for integration into clinical practice ...
Sciatti E., Merlo A., Scangiuzzi C., Limonta R., Gori M., D'Elia E., Aimo A., Vergaro G., Emdin M., Senni M.   +9 more
openaire   +3 more sources

Cellular Noise Suppression by the Regulator of G Protein Signaling Sst2 [PDF]

Molecular Cell, 2014
G proteins and their associated receptors process information from a variety of environmental stimuli to induce appropriate cellular responses. Generally speaking, each cell in a population responds within defined limits despite large variation in the expression of protein signaling components.
Gauri Dixit, Joshua B. Kelley, John R. Houser, Timothy C. Elston, Henrik Dohlman   +4 more
openalex   +3 more sources

Circulating Soluble Suppression of Tumorigenicity 2 Predicts Recurrence After Radiofrequency Ablation of Persistent Atrial Fibrillation

Frontiers in Cardiovascular Medicine, 2021
Objective: A more extensively fibrotic left atrium contributes to atrial fibrillation (AF) occurrence, persistence, and recurrence. The soluble suppression of tumorigenicity 2 (sST2) has emerged as a ventricular fibrotic biomarker for patients with heart
Ruopeng Tan, Ruopeng Tan, Haixu Yu, Xu Han, Yang Liu, Xiaolei Yang, Yun-Long Xia, Yun-Long Xia, Xiaomeng Yin   +8 more
doaj   +1 more source

The clinical value of serum sST2 and cfDNA in guiding evidence-based nursing care for children with severe pneumonia complicated by myocardial damage. [PDF]

J Med Biochem
Du M, Jia H, Zhao T, Liu Y, Wang D, Wang W.   +5 more
europepmc   +2 more sources

sST2 as a value-added biomarker in heart failure [PDF]

Clinica Chimica Acta, 2020
Soluble suppression of tumorigenicity-2 (sST2) is a biomarker widely investigated during the last few years. Its role has become clear in pathological conditions such as fibrosis and inflammation. From translational research to laboratory medicine, considerable efforts have been made to elucidate the features of sST2 biomarker and to consider its ...
Manuela Lotierzo, Anne Marie Dupuy, Eran Kalmanovich, François Roubille, Jean Paul Cristol   +4 more
openaire   +2 more sources

Serum sST2 levels predict severe exacerbation of asthma [PDF]

Respiratory Research, 2018
Neutrophilic inflammation is associated with poorly controlled asthma. Serum levels of sST2, a soluble IL-33 receptor, increase in neutrophilic lung diseases. We hypothesized that high serum sST2 levels in stable asthmatics are a predictor for exacerbation within a short duration.This prospective observational study evaluated the serum sST2 levels of ...
Masato Watanabe, Keitaro Nakamoto, Toshiya Inui, Mitsuru Sada, Kojiro Honda, Masaki Tamura, Yukari Ogawa, Takuma Yokoyama, Takeshi Saraya, Daisuke Kurai, Haruyuki Ishii, Hajime Takizawa   +11 more
openaire   +3 more sources

Role of soluble ST2 in short-term prediction of acute heart failure in acute ST-elevation myocardial infarction

Российский кардиологический журнал, 2021
Aim. To investigate the relationship of soluble ST2 (sST2) to acute heart failure (AHF) and compare the predictive value of sST2 and brain natriuretic peptide in patients with ST-elevation myocardial infarction (STEMI).Material and methods.
O. S. Donirova, K. V. Protasov, B. A. Donirov, E. V. Batunova   +3 more
doaj   +1 more source