Results 21 to 30 of about 218 (97)

Pentadecapeptide BPC 157 as Therapy for Inferior Caval Vein Embolization: Recovery of Sodium Laurate-Post-Embolization Syndrome in Rats [PDF]

Pharmaceuticals, 2023
After inferior caval vein embolization therapy, post-embolization syndrome (sodium laurate 10 mg/kg, 0.1 mL into rat inferior caval vein, assessment at 15, 30, 60 min, prime lung lesions, thromboemboli occluding lung vessels), as a severe occlusion ...
Ivan Maria Smoday, Ivan Krezic, Luka Kalogjera, Vlasta Vukovic, Helena Zizek, Marija Skoro, Katarina Kasnik Kovac, Hrvoje Vranes, Ivan Barisic, Suncana Sikiric, Sanja Strbe, Marijan Tepes, Katarina Oroz, Slavica Zubcic, Mirjana Stupnisek, Lidija Beketic Oreskovic, Ivana Kavelj, Luka Novosel, Matea Prenc, Sanja Barsic Ostojic, Ivan Dobric, Marko Sever, Alenka Boban Blagaic, Anita Skrtic, Mario Staresinic, Ivica Sjekavica, Sven Seiwerth, Predrag Sikiric   +27 more
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The effect of pentadecapeptide BPC 157 on hippocampal ischemia/reperfusion injuries in rats

Brain and Behavior, 2020
Background and purpose We focused on the, yet undescribed, therapy effect of the stable gastric pentadecapeptide BPC 157 in hippocampal ischemia/reperfusion injuries, after bilateral clamping of the common carotid arteries in rats.
Jakša Vukojević, Borna Vrdoljak, Dominik Malekinušić, Marko Siroglavić, Marija Milavić, Danijela Kolenc, Alenka Boban Blagaić, Lovorka Batelja, Domagoj Drmić, Sven Seiverth, Predrag Sikirić   +10 more
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Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats [PDF]

Journal of Orthopaedic Surgery and Research, 2019
Background We focused on the therapeutic effects of the stable gastric pentadecapeptide BPC 157 in spinal cord injury using a rat model. BPC 157, of which the LD1 has not been achieved, has been implemented as an anti-ulcer peptide in inflammatory bowel ...
Darko Perovic, Danijela Kolenc, Vide Bilic, Nenad Somun, Domagoj Drmic, Esmat Elabjer, Gojko Buljat, Sven Seiwerth, Predrag Sikiric   +8 more
doaj   +2 more sources

Stable Gastric Pentadecapeptide BPC 157 as a Therapy and Safety Key: A Special Beneficial Pleiotropic Effect Controlling and Modulating Angiogenesis and the NO-System [PDF]

Pharmaceuticals
Although approached through many concepts, the pleiotropic healing issue, specifically, maintaining/reestablishing tissue integrity, remains a central challenge in pharmacology, particularly when the process is misdirected or not properly controlled ...
Predrag Sikiric, Sven Seiwerth, Anita Skrtic, Mario Staresinic, Sanja Strbe, Antonia Vuksic, Suncana Sikiric, Dinko Bekic, Dragan Soldo, Boris Grizelj, Luka Novosel, Lidija Beketic Oreskovic, Ivana Oreskovic, Mirjana Stupnisek, Alenka Boban Blagaic, Ivan Dobric   +15 more
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Therapy Effect of the Stable Gastric Pentadecapeptide BPC 157 on Acute Pancreatitis as Vascular Failure-Induced Severe Peripheral and Central Syndrome in Rats [PDF]

Biomedicines, 2022
We revealed the therapy effect of the stable gastric pentadecapeptide BPC 157 (10 μg/kg, 10 ng/kg ig or po) with specific activation of the collateral rescuing pathways, the azygos vein, on bile duct ligation in particular, and acute pancreatitis as ...
Ivan Maria Smoday, Igor Petrovic, Luka Kalogjera, Hrvoje Vranes, Helena Zizek, Ivan Krezic, Slaven Gojkovic, Ivan Skorak, Klaudija Hriberski, Ivan Brizic, Milovan Kubat, Sanja Strbe, Ivan Barisic, Marija Sola, Eva Lovric, Marin Lozic, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +19 more
doaj   +2 more sources

Fourier Transform Infrared Spectroscopy Reveals Molecular Changes in Blood Vessels of Rats Treated with Pentadecapeptide BPC 157 [PDF]

Biomedicines, 2022
Recently, it was found that when confronted with major vessel occlusion and vascular failure, stable gastric pentadecapeptide BPC 157 therapy might rapidly functionally improve minor vessels to take over the function of disabled major vessels, reorganize
Ozren Gamulin, Katarina Oroz, Luka Coric, Maria Krajacic, Marko Skrabic, Vilim Dretar, Sanja Strbe, Jasminka Talapko, Martina Juzbasic, Ivan Krezic, Marin Lozic, Vasilije Stambolija, Helena Zizek, Ivana Jurca, Ivana Jurjevic, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +18 more
doaj   +2 more sources

Tendon, Ligament, and Muscle Injury, Osteotendinous, Myotendinous, and Muscle-to-Bone Junction Therapy Perspectives with Growth Factors and Stable Gastric Pentadecapeptide BPC 157—A Review [PDF]

Pharmaceuticals
As a novel theoretical and practical advantage, preclinical to clinical evidence, this systematic review of PRP, growth factors, and stable gastric pentadecapeptide BPC 157 efficacy in complex musculoskeletal and junctional injuries emphasizes the ...
Danijel Matek, Irena Matek, Mladen Japjec, Mirta Matek, Jakov Prenc, Borna Staresinic, Eva Staresinic, Andreja Prtoric, Suncana Sikiric, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Mario Kordic, Ante Tvrdeic, Sven Seiwerth, Predrag Sikiric, Alenka Boban Blagaic, Anita Skrtic, Ivan Bojanic, Ivan Dobric, Mario Staresinic   +20 more
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Stable Gastric Pentadecapeptide BPC 157 as Therapy After Surgical Detachment of the Quadriceps Muscle from Its Attachments for Muscle-to-Bone Reattachment in Rats [PDF]

Pharmaceutics
Background: This is a novel rat study using native peptide therapy, focused on reversing quadriceps muscle-to-bone detachment to reattachment and stable gastric pentadecapeptide BPC 157 per-oral therapy for shared muscle healing and function restoration.
Danijel Matek, Irena Matek, Eva Staresinic, Mladen Japjec, Ivan Bojanic, Alenka Boban Blagaic, Lidija Beketic Oreskovic, Ivana Oreskovic, Tihomil Ziger, Tomislav Novinscak, Ivan Krezic, Sanja Strbe, Martin Drinkovic, Filip Brkic, Jelena Popic, Anita Skrtic, Sven Seiwerth, Mario Staresinic, Predrag Sikiric, Ivica Brizic   +19 more
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Fourier Transform Infrared Spectroscopic Characterization of Aortic Wall Remodeling by Stable Gastric Pentadecapeptide BPC 157 After Unilateral Adrenalectomy in Rats [PDF]

Pharmaceuticals
Background: No Fourier transform infrared (FTIR) spectroscopy studies have directly evaluated adrenalectomy vessels, the technique’s established ability to probe collagen/elastin-associated spectral features and lipid peroxidation-related signatures, and
Ivan Maria Smoday, Vlasta Vukovic, Katarina Oroz, Hrvoje Vranes, Luka Kalogjera, Ozren Gamulin, Josipa Vlainic, Marija Milavic, Suncana Sikiric, Nora Nikolac Gabaj, Domagoj Marijancevic, Antun Koprivanac, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Ivan Barisic, Mario Kordic, Ante Tvrdeic, Sven Seiwerth, Predrag Sikiric, Alenka Boban Blagaic, Anita Skrtic   +21 more
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Conventional Antiarrhythmics Class I–IV, Late INa Inhibitors, IKs Enhancers, RyR2 Stabilizers, Gap Junction Modulators, Atrial-Selective Antiarrhythmics, and Stable Gastric Pentadecapeptide BPC 157 as Useful Cytoprotective Therapy in Arrhythmias [PDF]

Pharmaceuticals
This review examines and hypothesizes cytoprotection as a conceptual therapeutic criterion for antiarrhythmic drugs, referring to the possibility of suppressing arrhythmias while avoiding adverse electrophysiological or systemic effects.
Predrag Sikiric, Ivan Barisic, Mario Udovicic, Martina Lovric Bencic, Diana Balenovic, Dean Strinic, Gordana Zivanovic Posilovic, Sandra Uzun, Hrvoje Vranes, Ivan Krezic, Marin Lozic, Vasilije Stambolija, Ivica Premuzic Mestrovic, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Suncana Sikiric, Laura Tomic, Mario Kordic, Ante Tvrdeic, Sven Seiwerth, Alenka Boban Blagaic, Anita Skrtic   +22 more
doaj   +2 more sources