Results 31 to 40 of about 2,190,716 (112)

Tendon, Ligament, and Muscle Injury, Osteotendinous, Myotendinous, and Muscle-to-Bone Junction Therapy Perspectives with Growth Factors and Stable Gastric Pentadecapeptide BPC 157—A Review [PDF]

Pharmaceuticals
As a novel theoretical and practical advantage, preclinical to clinical evidence, this systematic review of PRP, growth factors, and stable gastric pentadecapeptide BPC 157 efficacy in complex musculoskeletal and junctional injuries emphasizes the ...
Danijel Matek, Irena Matek, Mladen Japjec, Mirta Matek, Jakov Prenc, Borna Staresinic, Eva Staresinic, Andreja Prtoric, Suncana Sikiric, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Mario Kordic, Ante Tvrdeic, Sven Seiwerth, Predrag Sikiric, Alenka Boban Blagaic, Anita Skrtic, Ivan Bojanic, Ivan Dobric, Mario Staresinic   +20 more
doaj   +2 more sources

Therapy Effect of the Stable Gastric Pentadecapeptide BPC 157 on Acute Pancreatitis as Vascular Failure-Induced Severe Peripheral and Central Syndrome in Rats [PDF]

Biomedicines, 2022
We revealed the therapy effect of the stable gastric pentadecapeptide BPC 157 (10 μg/kg, 10 ng/kg ig or po) with specific activation of the collateral rescuing pathways, the azygos vein, on bile duct ligation in particular, and acute pancreatitis as ...
Ivan Maria Smoday, Igor Petrovic, Luka Kalogjera, Hrvoje Vranes, Helena Zizek, Ivan Krezic, Slaven Gojkovic, Ivan Skorak, Klaudija Hriberski, Ivan Brizic, Milovan Kubat, Sanja Strbe, Ivan Barisic, Marija Sola, Eva Lovric, Marin Lozic, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +19 more
doaj   +2 more sources

Conventional Antiarrhythmics Class I–IV, Late INa Inhibitors, IKs Enhancers, RyR2 Stabilizers, Gap Junction Modulators, Atrial-Selective Antiarrhythmics, and Stable Gastric Pentadecapeptide BPC 157 as Useful Cytoprotective Therapy in Arrhythmias [PDF]

Pharmaceuticals
This review examines and hypothesizes cytoprotection as a conceptual therapeutic criterion for antiarrhythmic drugs, referring to the possibility of suppressing arrhythmias while avoiding adverse electrophysiological or systemic effects.
Predrag Sikiric, Ivan Barisic, Mario Udovicic, Martina Lovric Bencic, Diana Balenovic, Dean Strinic, Gordana Zivanovic Posilovic, Sandra Uzun, Hrvoje Vranes, Ivan Krezic, Marin Lozic, Vasilije Stambolija, Ivica Premuzic Mestrovic, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Suncana Sikiric, Laura Tomic, Mario Kordic, Ante Tvrdeic, Sven Seiwerth, Alenka Boban Blagaic, Anita Skrtic   +22 more
doaj   +2 more sources

Stable Gastric Pentadecapeptide BPC 157 as Therapy After Surgical Detachment of the Quadriceps Muscle from Its Attachments for Muscle-to-Bone Reattachment in Rats [PDF]

Pharmaceutics
Background: This is a novel rat study using native peptide therapy, focused on reversing quadriceps muscle-to-bone detachment to reattachment and stable gastric pentadecapeptide BPC 157 per-oral therapy for shared muscle healing and function restoration.
Danijel Matek, Irena Matek, Eva Staresinic, Mladen Japjec, Ivan Bojanic, Alenka Boban Blagaic, Lidija Beketic Oreskovic, Ivana Oreskovic, Tihomil Ziger, Tomislav Novinscak, Ivan Krezic, Sanja Strbe, Martin Drinkovic, Filip Brkic, Jelena Popic, Anita Skrtic, Sven Seiwerth, Mario Staresinic, Predrag Sikiric, Ivica Brizic   +19 more
doaj   +2 more sources

Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights. [PDF]

World J Gastroenterol, 2017
AIM: To provide new insights in treatment of colitis and ischemia and reperfusion in rats using stable gastric pentadecapeptide BPC 157. ----- METHODS: Medication [BPC 157, L-NAME, L-arginine (alone/combined), saline] was bath at the blood ...
Duzel A, Vlainic J, Antunovic M, Malekinusic D, Vrdoljak B, Samara M, Gojkovic S, Krezic I, Vidovic T, Bilic Z, Knezevic M, Sever M, Lojo N, Kokot A, Kolovrat M, Drmic D, Vukojevic J, Kralj T, Kasnik K, Siroglavic M, Seiwerth S, Sikiric P.   +21 more
europepmc   +6 more sources

BPC 157 Therapy: Targeting Angiogenesis and Nitric Oxide’s Cytotoxic and Damaging Actions, but Maintaining, Promoting, or Recovering Their Essential Protective Functions. Comment on Józwiak et al. Multifunctionality and Possible Medical Application of the BPC 157 Peptide—Literature and Patent Review. Pharmaceuticals 2025, 18, 185 [PDF]

Pharmaceuticals
The healing issue is a central, not completely understood, problem in pharmacology, approached by many concepts. One of the most well-known is Robert’s and Szabo’s concept of cytoprotection, which holds innate cell (epithelial (Robert), endothelial ...
Predrag Sikiric, Sven Seiwerth, Anita Skrtic, Mario Staresinic, Sanja Strbe, Antonia Vuksic, Suncana Sikiric, Dinko Bekic, Dragan Soldo, Boris Grizelj, Luka Novosel, Lidija Beketic Oreskovic, Ivana Oreskovic, Mirjana Stupnisek, Alenka Boban Blagaic, Ivan Dobric   +15 more
doaj   +2 more sources

Protective effects of BPC 157 in rats with experimentally induced lower extremity ischemia-reperfusion injury [PDF]

Scientific Reports
Ischemia–reperfusion (I/R) injury remains a major complication in peripheral arterial disease, characterized by oxidative stress, inflammation, and apoptosis.
Alperen Kutay Yıldırım, Hüseyin Demirtaş, Abdullah Özer, Mustafa Arslan   +3 more
doaj   +2 more sources

Stable Gastric Pentadecapeptide BPC 157 Therapy: Effect on Reperfusion Following Maintained Intra-Abdominal Hypertension (Grade III and IV) in Rats. [PDF]

Pharmaceuticals (Basel), 2023
Tepes M, Krezic I, Vranes H, Smoday IM, Kalogjera L, Zizek H, Vukovic V, Oroz K, Kovac KK, Madzar Z, Rakic M, Miskic B, Sikiric S, Barisic I, Strbe S, Antunovic M, Novosel L, Kavelj I, Vlainic J, Dobric I, Staresinic M, Skrtic A, Seiwerth S, Blagaic AB, Sikiric P.   +24 more
europepmc   +2 more sources

Tracheocutaneous Fistula Resolved by Pentadecapeptide BPC 157 Therapy Through the NO-System—Triple NO-Agent Approach in Rats [PDF]

Pharmaceuticals
Background/Objectives: This 7-day rat tracheocutaneous fistula study considered the not-studied issues of tracheocutaneous fistula course, wound healing, and fistula in the NO-system relations.
Goran Madzarac, Tomislav Becejac, Toni Penovic, Dominik Drazenovic, Lucija Kralj, Marta Popović Dolic, Suncana Sikiric, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Ana Maria Tubikanec, Mihovil Penavic, Hrvoje Vranes, Ivan Krezic, Mario Kordic, Antun Koprivanac, Tinka Vidovic, Josipa Vlainic, Dinko Stancic Rokotov, Alenka Boban Blagaic, Sven Seiwerth, Anita Skrtic, Predrag Sikiric   +22 more
doaj   +2 more sources

Corrigendum: Stable Gastric Pentadecapeptide BPC 157 Therapy for Primary Abdominal Compartment Syndrome in Rats [PDF]

Frontiers in Pharmacology, 2022
Marijan Tepes, Marijan Tepes, Marijan Tepes, Marijan Tepes, Slaven Gojkovic, Ivan Krezic, Helena Zizek, Hrvoje Vranes, Zrinko Madzar, Goran Santak, Lovorka Batelja, Marija Milavic, Suncana Sikiric, Ivica Kocman, Karol Simonji, Mariam Samara, Mario Knezevic, Ivan Barisic, Eva Lovric, Sanja Strbe, Antonio Kokot, Ivica Sjekavica, Toni Kolak, Anita Skrtic, Sven Seiwerth, Alenka Boban Blagaic, Predrag Sikiric   +26 more
doaj   +2 more sources