BPC 157 Therapy: Targeting Angiogenesis and Nitric Oxide’s Cytotoxic and Damaging Actions, but Maintaining, Promoting, or Recovering Their Essential Protective Functions. Comment on Józwiak et al. Multifunctionality and Possible Medical Application of the BPC 157 Peptide—Literature and Patent Review. Pharmaceuticals 2025, 18, 185 [PDF]
The healing issue is a central, not completely understood, problem in pharmacology, approached by many concepts. One of the most well-known is Robert’s and Szabo’s concept of cytoprotection, which holds innate cell (epithelial (Robert), endothelial ...
Predrag Sikiric +15 more
doaj +2 more sources
Stable Gastric Pentadecapeptide BPC 157 Therapy: Effect on Reperfusion Following Maintained Intra-Abdominal Hypertension (Grade III and IV) in Rats [PDF]
Blaženka MIŠKIĆ +2 more
exaly +2 more sources
Tracheocutaneous Fistula Resolved by Pentadecapeptide BPC 157 Therapy Through the NO-System—Triple NO-Agent Approach in Rats [PDF]
Background/Objectives: This 7-day rat tracheocutaneous fistula study considered the not-studied issues of tracheocutaneous fistula course, wound healing, and fistula in the NO-system relations.
Goran Madzarac +22 more
doaj +2 more sources
Corrigendum: Stable Gastric Pentadecapeptide BPC 157 Therapy for Primary Abdominal Compartment Syndrome in Rats [PDF]
Marijan Tepes +26 more
doaj +2 more sources
Cytoprotection as a Unifying Strategy for Hemorrhage and Thrombosis: The Role of BPC 157 and Related Therapeutics [PDF]
This review presents an innovative and timely exploration of how cytoprotection can serve as a cohesive therapeutic approach by which to address the hemorrhage–thrombosis paradox.
Predrag Sikiric +23 more
doaj +2 more sources
Challenge of Corneal Ulcer Healing: A Novel Conceptual Framework, the “Triad” of Corneal Ulcer Healing/Corneal Neovascularization/Intraocular Pressure, and Avascular Tendon Healing, for Evaluation of Corneal Ulcer Therapy, Therapy of Neovascularization, Glaucoma Therapy, and Pentadecapeptide BPC 157 Efficacy [PDF]
To better address the challenge of corneal ulcer healing, with already available standard agents, and those recently introduced, such as stable gastric pentadecapeptide BPC 157, we introduced a novel conceptual framework—the “triad” of corneal ulcer ...
Sanja Masnec +18 more
doaj +2 more sources
Effect of Pentadecapeptide BPC 157 on Hypercalcaemia in Rats
Isolated from gastric juice stable pentadecapeptide BPC 157 has already shown cytoprotective and organoprotective properties. Beneficial effects of BPC 157 on various organic systems such as cardiovascular, digestive, skeletomuscular system have already ...
Matej Lacković +2 more
doaj +1 more source
We focused on histological aspects of the cytoprotective effects of Stable gastric pentadecapeptide BPC 157 after stomach perforation in rats was performed.
Petra Horvat +2 more
doaj +1 more source
Stable gastric pentadecapeptide BPC 157
Considering peptidergic drugs, many cytokines, enzymes, clotting factors registered for the use as therapeutic agents in specific conditions, they are mainly given by injection, only occasionally by other routes. Also, to ascertain delivery and activity, they use different carriers, peptide+carrier complex may provide significant methodology/activity ...
Sikirić, Predrag +3 more
+9 more sources
The aim of this study is to investigate the effect of stable gastric pentadecapeptide BPC 157 effect on counteracting haematoma and swelling caused by spinal cord injury.
Luka Ćorić +3 more
doaj +1 more source

