Results 51 to 60 of about 2,190,716 (112)

Fourier Transform Infrared Spectroscopy Reveals Molecular Changes in Blood Vessels of Rats Treated with Pentadecapeptide BPC 157

Biomedicines, 2022
Recently, it was found that when confronted with major vessel occlusion and vascular failure, stable gastric pentadecapeptide BPC 157 therapy might rapidly functionally improve minor vessels to take over the function of disabled major vessels, reorganize
Ozren Gamulin, Katarina Oroz, Luka Coric, Maria Krajacic, Marko Skrabic, Vilim Dretar, Sanja Strbe, Jasminka Talapko, Martina Juzbasic, Ivan Krezic, Marin Lozic, Vasilije Stambolija, Helena Zizek, Ivana Jurca, Ivana Jurjevic, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +18 more
doaj   +1 more source

Novelties regarding pentadecapeptide BPC-157

, 2021
Stable gastric pentadecapeptide BPC-157 is a novel anti-ulcer peptide, used in trials for the treatment of ulcerative colitis and now multiple sclerosis.
Vrdoljak, Borna, Amić, Fedor, Zovak, Mario   +2 more
core   +1 more source

Intragastric Application of Aspirin, Clopidogrel, Cilostazol, and BPC 157 in Rats: Platelet Aggregation and Blood Clot

Oxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019
We suggest that the stable gastric pentadecapeptide BPC 157 may rescue thrombocyte function. We focused on the antithrombotic agent aspirin, clopidogrel, and cilostazol application in rats; arachidonic acid, ADP, collagen, and arachidonic acid/PGE1 platelet aggregation (aggregometry) and blood clot viscoelastic properties (thromboelastometry); and the ...
Sanja Konosic, Mate Petricevic, Visnja Ivancan, Lucija Konosic, Eleonora Goluza, Branimir Krtalic, Domagoj Drmic, Mirjana Stupnisek, Sven Seiwerth, Predrag Sikiric, Aleksandar Kibel   +10 more
wiley   +1 more source

Novel Therapeutic Effects in Rat Spinal Cord Injuries: Recovery of the Definitive and Early Spinal Cord Injury by the Administration of Pentadecapeptide BPC 157 Therapy

Current Issues in Molecular Biology, 2022
Recently, marked therapeutic effects pertaining to the recovery of injured rat spinal cords (1 min compression injury of the sacrocaudal spinal cord (S2-Co1) resulting in tail paralysis) appeared after a single intraperitoneal administration of the ...
Darko Perovic, Marija Milavic, Stjepan Dokuzovic, Ivan Krezic, Slaven Gojkovic, Hrvoje Vranes, Igor Bebek, Vide Bilic, Nenad Somun, Ivan Brizic, Ivan Skorak, Klaudija Hriberski, Suncana Sikiric, Eva Lovric, Sanja Strbe, Milovan Kubat, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +19 more
doaj   +1 more source

BPC 157 Therapy and the Permanent Occlusion of the Superior Sagittal Sinus in Rat: Vascular Recruitment

Biomedicines, 2021
We show the complex syndrome of the occluded superior sagittal sinus, brain swelling and lesions and multiple peripheral organs lesions in rat. Recovery goes centrally and peripherally, with the stable gastric pentadecapeptide BPC 157, which alleviated ...
Slaven Gojkovic, Ivan Krezic, Hrvoje Vranes, Helena Zizek, Domagoj Drmic, Katarina Horvat Pavlov, Andrea Petrovic, Lovorka Batelja Vuletic, Marija Milavic, Suncana Sikiric, Irma Stilinovic, Mariam Samara, Mario Knezevic, Ivan Barisic, Ivica Sjekavica, Eva Lovric, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +18 more
doaj   +1 more source

Prolonged Esophagitis After Primary Dysfunction of the Pyloric Sphincter in the Rat and Therapeutic Potential of the Gastric Pentadecapeptide BPC 157

Journal of Pharmacological Sciences, 2007
Seven or fourteen days or twelve months after suturing one tube into the pyloric sphincter (removed by peristalsis by the seventh day), rats exhibit prolonged esophagitis with a constantly lowered pressure not only in the pyloric, but also in the lower ...
Ivan Dobric, Petar Drvis, Igor Petrovic, Drazen Shejbal, Luka Brcic, Alenka Boban Blagaic, Lovorka Batelja, Marko Sever, Neven Kokic, Ante Tonkic, Ivan Zoricic, Sandro Mise, Mario Staresinic, Bozo Radic, Ana Jakir, Jaksa Babel, Spomenko Ilic, Tihomir Vuksic, Ivan Jelic, Tomislav Anic, Sven Seiwerth, Predrag Sikiric   +21 more
doaj   +1 more source

Over-Dose Lithium Toxicity as an Occlusive-like Syndrome in Rats and Gastric Pentadecapeptide BPC 157

Biomedicines, 2021
Due to endothelial impairment, high-dose lithium may produce an occlusive-like syndrome, comparable to permanent occlusion of major vessel-induced syndromes in rats; intracranial, portal, and caval hypertension, and aortal hypotension; multi-organ ...
Sanja Strbe, Slaven Gojkovic, Ivan Krezic, Helena Zizek, Hrvoje Vranes, Ivan Barisic, Dean Strinic, Tatjana Orct, Jaksa Vukojevic, Spomenko Ilic, Eva Lovric, Darija Muzinic, Danijela Kolenc, Igor Filipčić, Zoran Zoricic, Darko Marcinko, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +19 more
doaj   +1 more source

An Experimental Model of Prolonged Esophagitis With Sphincter Failure in the Rat and the Therapeutic Potential of Gastric Pentadecapeptide BPC 157

Journal of Pharmacological Sciences, 2006
We report a simple novel rat model that combines prolonged esophagitis and parallel sphincters failure. The anti-ulcer gastric pentadecapeptide BPC 157, which was found to be stable in gastric juice, and is being evaluated in inflammatory bowel disease ...
Igor Petrovic, Ivan Dobric, Petar Drvis, Drazen Shejbal, Luka Brcic, Alenka Boban Blagaic, Lovorka Batelja, Neven Kokic, Ante Tonkic, Stjepan Mise, Tomislav Baotic, Mario Staresinic, Bozo Radic, Ana Jakir, Tihomir Vuksic, Tomislav Anic, Sven Seiwerth, Predrag Sikiric   +17 more
doaj   +1 more source

Pentadecapeptide BPC 157 and Rac 1 inhibitors [PDF]

, 2016
UVOD: Rac1 je mali signalizirajući G-protein koji može aktivirati NF-kappaB. Pentadekapeptid BPC 157 smanjuje transkripciju Vcam-1 u NF-kappaB signalnom putu kao i neki NF-kappaB inhibitori te suprimira da ERK inducira Vcam-1 preko NF-kappaB aktivacije ...
Vidović, Tinka
core   +1 more source

Stable gastric pentadecapeptide BPC 157 and insulin induced gastric lesions in rats.

Journal of physiology and pharmacology, 2009
The stable gastric pentadecapeptid BPC 157 (GEPPGKPADDAGLV, M.W. 1419) is a small anti- ulcer peptide efficient in inflammatory bowed disease trials (PL 14736) and various wound tretment, no toxiicity reported. Interestingly, it may have therapeutic effect on acute panckeatitis and act protzectively on endothelium, affects many central disturbances and
Ilić, S, Mester, M, Filipović, M, Sever, M, Klicek, R, Barisic, I, Zoričić, Z, Bilić, V, Berkopić, L, Brcic, L, Brcic, I, Kolenc, D, Seiwerth, S, Sikiric P   +13 more
openaire   +3 more sources