Results 41 to 50 of about 218 (97)

Antinociceptive Effect of BPC-157 in the Formalin-induced Pain Model [PDF]

open access: yesKosin Medical Journal, 2021
Objectives Body protective compound-157 (BPC-157) is a stable gastric pentadecapeptide that has been effective in trials aiming to increase wound healing capabilities and decrease inflammatory cell influx, including studies on the healing of muscles and ...
Sang Yoong Park   +6 more
doaj   +1 more source

Effects of Stable gastric pentadecapeptide BPC 157 and osteogenic material on bone regeneration in mandibula

open access: yesLiječnički vjesnik, 2023
INTRODUCTION: Our work was focused on the effect of Stable gastric pentadecapeptide BPC-157 on the osteointegration of synthetic hydroxyapatite in a 2mm cavity located on the left mandibular body.
Andrej Vrdoljak   +2 more
doaj   +1 more source

The effects of pentadecapeptide BPC 157 on the healing of the incisional skin wound in rats

open access: yesLiječnički vjesnik, 2023
Healing of the wounds is accomplished by: the resolution of vessel constriction, the primary platelet plug formation, the fibrin mesh which acts to stabilize the platelet plug and finally resolution of the clot.
Luka Kalogjera, Ivan Maria Smoday
doaj   +1 more source

Pentadecapeptide BPC 157 and the central nervous system

open access: yesNeural Regeneration Research, 2022
We reviewed the pleiotropic beneficial effects of the stable gastric pentadecapeptide BPC 157, three very recent demonstrations that may be essential in the gut-brain and brain-gut axis operation, and therapy application in the central nervous system ...
Jakša Vukojevic   +11 more
doaj   +1 more source

In relation to NO‐System, Stable Pentadecapeptide BPC 157 Counteracts Lidocaine‐Induced Adverse Effects in Rats and Depolarisation In Vitro

open access: yesEmergency Medicine International, Volume 2020, Issue 1, 2020., 2020
Recently, the pentadecapeptide BPC 157‐induced counteraction of bupivacaine cardiotoxicity has been reported. Medication includes (i) lidocaine‐induced local anesthesia via intraplantar application and axillary and spinal (L4‐L5) intrathecal block, (ii) lidocaine‐induced arrhythmias, (iii) convulsions, and (iv) lidocaine‐induced HEK293 cell ...
Marin Lozic   +17 more
wiley   +1 more source

Pentadecapeptide BPC 157, in Clinical Trials as a Therapy for Inflammatory Bowel Disease (PL14736), Is Effective in the Healing of Colocutaneous Fistulas in Rats: Role of the Nitric Oxide-System

open access: yesJournal of Pharmacological Sciences, 2008
We focused on the therapeutic effect of the stable gastric pentadecapeptide BPC 157 and how its action is related to nitric oxide (NO) in persistent colocutaneous fistula in rats (at 5 cm from anus, colon defect of 5 mm, skin defect of 5 mm); this ...
Robert Klicek   +19 more
doaj   +1 more source

Pentadecapeptide BPC 157 Reduces Bleeding and Thrombocytopenia after Amputation in Rats Treated with Heparin, Warfarin, L-NAME and L-Arginine. [PDF]

open access: yesPLoS ONE, 2015
BPC 157 is a stable gastric pentadecapeptide recently implicated with a role in hemostasis. While NO is largely implicated in hemostatic mechanisms, in tail-amputation-models under heparin- and warfarin-administration, both the NO-synthase (NOS)-blocker,
Mirjana Stupnisek   +11 more
doaj   +1 more source

Intragastric Application of Aspirin, Clopidogrel, Cilostazol, and BPC 157 in Rats: Platelet Aggregation and Blood Clot

open access: yesOxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019
We suggest that the stable gastric pentadecapeptide BPC 157 may rescue thrombocyte function. We focused on the antithrombotic agent aspirin, clopidogrel, and cilostazol application in rats; arachidonic acid, ADP, collagen, and arachidonic acid/PGE1 platelet aggregation (aggregometry) and blood clot viscoelastic properties (thromboelastometry); and the ...
Sanja Konosic   +10 more
wiley   +1 more source

Novel Therapeutic Effects in Rat Spinal Cord Injuries: Recovery of the Definitive and Early Spinal Cord Injury by the Administration of Pentadecapeptide BPC 157 Therapy

open access: yesCurrent Issues in Molecular Biology, 2022
Recently, marked therapeutic effects pertaining to the recovery of injured rat spinal cords (1 min compression injury of the sacrocaudal spinal cord (S2-Co1) resulting in tail paralysis) appeared after a single intraperitoneal administration of the ...
Darko Perovic   +19 more
doaj   +1 more source

BPC 157 Therapy and the Permanent Occlusion of the Superior Sagittal Sinus in Rat: Vascular Recruitment

open access: yesBiomedicines, 2021
We show the complex syndrome of the occluded superior sagittal sinus, brain swelling and lesions and multiple peripheral organs lesions in rat. Recovery goes centrally and peripherally, with the stable gastric pentadecapeptide BPC 157, which alleviated ...
Slaven Gojkovic   +18 more
doaj   +1 more source

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