Results 211 to 220 of about 15,919 (247)
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Stable Isotope Dilution Mass Spectrometric Assay for PRPP Using Enzymatic Procedures
Nucleosides, Nucleotides and Nucleic Acids, 20115-Phosphoribosyl-1-pyrophosphate (PRPP) is an important regulator of de novo purine synthesis. A method for the measurement of PRPP in erythrocytes was designed, which is based on the determination of [(13)C(5)]glutamate derived from [(13)C(5)]glutamine following the utilization of PRPP by the action of amidophosphoribosyltransferase. The present study
Y, Shinohara +6 more
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Diabetes, 1997
Insulin levels in humans were measured by a new assay, the isotope dilution assay (IDA), based on stable isotope dilution mass spectrometry. A known amount of a deuterated analog of insulin was used as an internal standard and added to the serum samples before sample processing.
Stöcklin R +6 more
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Insulin levels in humans were measured by a new assay, the isotope dilution assay (IDA), based on stable isotope dilution mass spectrometry. A known amount of a deuterated analog of insulin was used as an internal standard and added to the serum samples before sample processing.
Stöcklin R +6 more
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Determination of potent odourants in roasted coffee by stable isotope dilution assays
Flavour and Fragrance Journal, 1995AbstractStable isotope dilution assays were developed for 14 important odourants of roasted coffee. The following amounts (mg/kg) were found in the Arabica (I) and the Robusta (II) coffees: 2‐furfurylthiol (1.08 I, 1.73 II), methional (0.24 I, 0.095 II), 3‐mercapto‐3‐methylbutyl formate (0.13 I, 0.115 II), 2‐ethyl‐3‐5‐dimethylpyrazine (0.33 I, 0.94 II),
P. Semmelroch +3 more
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Analytical Biochemistry, 2010
New stable isotope dilution assays were developed for the simultaneous quantitation of the folates 5-methyltetrahydrofolic acid, 5-formyltetrahydrofolic acid, tetrahydrofolic acid, 10-formylfolic acid, and folic acid as well as for their catabolites para-aminobenzoylglutamate (pABG) and acetyl-para-aminobenzoylglutamate (ApABG) in clinical samples. The
Moench, Sabine +3 more
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New stable isotope dilution assays were developed for the simultaneous quantitation of the folates 5-methyltetrahydrofolic acid, 5-formyltetrahydrofolic acid, tetrahydrofolic acid, 10-formylfolic acid, and folic acid as well as for their catabolites para-aminobenzoylglutamate (pABG) and acetyl-para-aminobenzoylglutamate (ApABG) in clinical samples. The
Moench, Sabine +3 more
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Journal of Agricultural and Food Chemistry, 2011
Two stable isotope dilution assays were developed for the quantitation of acrolein in fats and oils using [(13)C(3)]-acrolein as the internal standard. First, a direct GC-MS headspace method, followed by an indirect GC-MS method using derivatization with pentafluorophenyl hydrazine, was established.
Alice, Ewert +2 more
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Two stable isotope dilution assays were developed for the quantitation of acrolein in fats and oils using [(13)C(3)]-acrolein as the internal standard. First, a direct GC-MS headspace method, followed by an indirect GC-MS method using derivatization with pentafluorophenyl hydrazine, was established.
Alice, Ewert +2 more
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1984
Secoverine (formula below) is a new gastro-intestinal muscle relaxant whose pharmacokinetics and disposition are currently being investigated in different animal species and man. The drug is administered as a racemate of which only the (+) enantiomer has pharmacological activity.
H. de Bree +5 more
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Secoverine (formula below) is a new gastro-intestinal muscle relaxant whose pharmacokinetics and disposition are currently being investigated in different animal species and man. The drug is administered as a racemate of which only the (+) enantiomer has pharmacological activity.
H. de Bree +5 more
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Rapid degradation of the mycotoxin patulin in man quantified by stable isotope dilution assays
Food Additives and Contaminants, 2003The absorption and degradation of the mycotoxin patulin in man was quantified by using a recently developed stable isotope dilution assay. Application of this currently most sensitive method revealed a patulin content less than 200 ng l(-1) in the blood serum of five consumers of apple juice.
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Quantification of 1,8‐cineole and of its metabolites in humans using stable isotope dilution assays
Molecular Nutrition & Food Research, 2010AbstractThe metabolism of 1,8‐cineole after ingestion of sage tea was studied. After application of the tea, the metabolites 2‐hydroxy‐1,8‐cineole, 3‐hydroxy‐1,8‐cineole, 9‐hydroxy‐1,8‐cineole and, for the first time in humans, 7‐hydroxy‐1,8‐cineole were identified in plasma and urine of one volunteer.
Kathie, Horst, Michael, Rychlik
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Quantitative Analysis of Beer Aromatic Alcohols Using Stable Isotope Dilution Assay
Journal of the American Society of Brewing Chemists, 2002A quantitative assay of beer aromatic alcohols was developed using gas chromatography (GC) in conjunction with stable isotope dilution analysis (SIDA). Quantification using SIDA is not subject to instrumental and/or sample manipulation variation as any analytical variation has a similar effect on the aromatic alcohols and their corresponding labeled ...
Jean-Pierre Dufour +6 more
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Quantitative determination of .beta.-damascenone in foods using a stable isotope dilution assay
Journal of Agricultural and Food Chemistry, 1991The aim was to develop such an assay for β-damascenone and to apply it for the analysis of roasted coffee (powder and brew), black tea, honey and beer samples.
Alina Sen +3 more
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