Results 11 to 20 of about 2,093,866 (195)

An investigation into the archaeological application of carbon stable isotope analysis used to establish crop water availability: solutions and ways forward [PDF]

open access: yes, 2011
Carbon stable isotope analysis of charred cereal remains is a relatively new method employed by archaeological scientists to investigate ancient climate and irrigation regimes. The aim of this study was to assess the effect of environmental variables
Jenkins, Emma L.   +2 more
core   +10 more sources

Stable isotopic labeling in proteomics [PDF]

open access: yesPROTEOMICS, 2008
AbstractLabeling of proteins and peptides with stable heavy isotopes (deuterium, carbon‐13, nitrogen‐15, and oxygen‐18) is widely used in quantitative proteomics. These are either incorporated metabolically in cells and small organisms, or postmetabolically in proteins and peptides by chemical or enzymatic reactions.
Gevaert, Kris   +5 more
openaire   +3 more sources

Structure and flow of carbon and nitrogen to the western Irish Sea Nephrops norvegicus fishery: a stable isotope approach. [PDF]

open access: yes, 2008
PhDStable isotope analysis was used to describe the structure and flow of organic matter (carbon and nitrogen) from primary production in the water column to the benthos, and into secondary production that supports a fishery for the lobster Nephrops ...
Hill, Jacqueline M
core   +4 more sources

A large-scale LC-MS dataset of murine liver proteome from time course of heavy water metabolic labeling

open access: yesScientific Data, 2023
Metabolic stable isotope labeling with heavy water followed by liquid chromatography coupled with mass spectrometry (LC-MS) is a powerful tool for in vivo protein turnover studies.
Henock M. Deberneh   +8 more
doaj   +1 more source

Rapid and reliable RNA resonance assignment by combining chemical and enzymatic stable isotope labeling

open access: yesJournal of Magnetic Resonance Open, 2022
In this work a rapid RNA assignment approach by combining chemical and enzymatic 13C and 15N stable isotope labeling is introduced. We exemplify the assignment strategy for imino N1H1 purine and N3H3 pyrimidine and aromatic C6H6 pyrimidine, C8H8 purine ...
David Klingler   +3 more
doaj   +1 more source

Stable-isotope labeling with amino acids in nematodes [PDF]

open access: yesNature Methods, 2011
We describe an approach for accurate quantitation of global protein dynamics in Caenorhabditis elegans. We adapted stable-isotope labeling with amino acids in cell culture (SILAC) for nematodes by feeding worms a heavy lysine- and heavy arginine-labeled Escherichia coli strain and report a genetic solution to elminate the problem of arginine-to-proline
Larance, Mark   +8 more
openaire   +4 more sources

mfapy: An open-source Python package for 13C-based metabolic flux analysis

open access: yesMetabolic Engineering Communications, 2021
13C-based metabolic flux analysis (13C-MFA) is an essential tool for estimating intracellular metabolic flux levels in metabolic engineering and biology.
Fumio Matsuda   +6 more
doaj   +1 more source

Metabolic Flux Analysis—Linking Isotope Labeling and Metabolic Fluxes

open access: yesMetabolites, 2020
Metabolic flux analysis (MFA) is an increasingly important tool to study metabolism quantitatively. Unlike the concentrations of metabolites, the fluxes, which are the rates at which intracellular metabolites interconvert, are not directly measurable ...
Yujue Wang   +4 more
doaj   +1 more source

Analytical Considerations of Stable Isotope Labelling in Lipidomics [PDF]

open access: yesBiomolecules, 2018
Over the last two decades, lipids have come to be understood as far more than merely components of cellular membranes and forms of energy storage, and are now also being implicated to play important roles in a variety of diseases, with lipid biomarker research one of the most widespread applications of lipidomic techniques both in research and in ...
Alexander Triebl, Markus R. Wenk
openaire   +3 more sources

Stable isotope dilution techniques for assessing vitamin A status and bioefficacy of provitamin A carotenoids in humans. [PDF]

open access: yes, 2005
Vitamin A deficiency is a major global public health problem. Among the variety of techniques that are available for assessing human vitamin A status, evaluating the provitamin A nutritional values of foodstuffs and estimating human vitamin A ...
Judy D Ribaya-Mercado   +19 more
core   +1 more source

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