Results 61 to 70 of about 6,735 (211)

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

Allergy, EarlyView.
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud, Emil M. Pallesen, Ziao Zeng, Martin R. J. Namini, Chella Krishna Vadivel, Lise Mette Rahbek Gjerdrum, Lang Yan, Sana Ahmad, Lise M. Lindahl, Michael Bzorek, Maria R. Kamstrup, Saptaswa Dey, Sisse Rye Ostrowski, Erik Sørensen, Pia Rantakari, Charlotte Menne Bonefeld, Carsten Geisler, Anders Woetmann, Riitta Lahesmaa, Lars Iversen, Peter Wolf, Thomas Litman, Terkild B. Buus, Niels Ødum   +23 more
wiley   +1 more source

Functional and Immunological Studies Revealed a Second Superantigen Toxin in Staphylococcal Enterotoxin C Producing Staphylococcus aureus Strains

Toxins, 2022
Staphylococcus aureus is a human and animal pathogen as well as a commensal bacterium. It can be a causative agent of severe, life-threatening infections with high mortality, e.g., toxic shock syndrome, septic shock, and multi-organ failure. S.
Andreas Roetzer, Nina Model, Jakob Laube, Yvonne Unterhumer, Guenter Haller, Martha M. Eibl   +5 more
doaj   +1 more source

Transport and processing of staphylococcal enterotoxin A [PDF]

Applied and Environmental Microbiology, 1985
A larger-molecular-weight precursor of enterotoxin A was found in membranes of Staphylococcus aureus and was shown to be the kinetic precursor to the extracellular form of the toxin. Subcellular fractionation revealed that mature enterotoxin A was transiently associated with the cell wall before being released to the extracellular environment.
K K, Christianson, R K, Tweten, J J, Iandolo   +2 more
openaire   +2 more sources

Divergent Paths: A Comprehensive Review of Mechanisms and Clinical Implications in Atopic Dermatitis and Psoriasis

Allergy, EarlyView.
ABSTRACT Atopic dermatitis and psoriasis are two common cutaneous chronic inflammatory diseases. Although they share similar immunological mechanisms, their clinical implications in the patient are different. This review compares both diseases from different points of view such as genetics, natural history, triggers of disease, and skin barrier defects
Tali Czarnowicki, Kazunari Sugita, Zenas Yiu, Sandra Díez‐Ribas, Irene Garcia‐Jimenez, Emma Guttman‐Yassky, Luis F. Santamaria‐Babí   +6 more
wiley   +1 more source

Subinhibitory concentrations of perilla oil affect the expression of secreted virulence factor genes in Staphylococcus aureus. [PDF]

PLoS ONE, 2011
BACKGROUND: The pathogenicity of staphylococcus aureus is dependent largely upon its ability to secrete a number of virulence factors, therefore, anti-virulence strategy to combat S. aureus-mediated infections is now gaining great interest.
Jiazhang Qiu, Xiaoran Zhang, Mingjing Luo, Hongen Li, Jing Dong, Jianfeng Wang, Bingfeng Leng, Xiaoliang Wang, Haihua Feng, Wenzhi Ren, Xuming Deng   +10 more
doaj   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Staphylococcal enterotoxins: molecular aspects and detection methods

, 2010
Members of the Staphylococcus genus, especially Staphylococcus aureus, are the most common pathogens found in hospitals and in community-acquired infections. Some of their pathogenicity is associated with enzyme and toxin production.
Cunha, Maria de Lourdes Ribeiro de Souza da, Vasconcelos, Nathalie Gaebler   +1 more
core   +2 more sources

Detection of Enterotoxigenic Staphylococcus aureus Strains in Raw Milk of Cows Reared in Erbil Province/Iraq

Zanco Journal of Pure and Applied Sciences, 2019
Raw milk is usually contaminated with enterotoxin-producing Staphylococcus ¬aureus, which is regularly associated with staphylococcal food poisoning. The present study was conducted to investigate the occurrence of Staphylococcus aureus and enterotoxin ...
Nishtiman Saeed Hasan, Dana F. Hoshyar
doaj   +1 more source

Regulation of staphylococcal enterotoxin B [PDF]

Infection and Immunity, 1977
The effect of glucose and the glucose analogues 2-deoxyglucose and alpha-methyl-glucoside on the synthesis and regulation of staphylococcal enterotoxin B was examined. The attenuating effect of glucose on staphylococcal enterotoxin B synthesis was observed.
J J, Iandolo, W M, Shafer
openaire   +2 more sources

Role of CD44 and its v7 isoform in staphylococcal enterotoxin B-induced toxic shock : CD44 deficiency on hepatic mononuclear cells leads to reduced activation-induced apoptosis that results in increased liver damage [PDF]

, 2005
Exposure to bacterial superantigens such as staphylococcal enterotoxin B (SEB) leads to the induction of toxic shock syndrome which results in multiorgan failure, including liver damage.
Fisher, M., Andras K. Szakal, Ursula Gunthert, Robert J. McKallip, Szakal, A. K., Michael Fisher, Mitzi Nagarkatti, McKallip, R. J., Gunthert, U., Nagarkatti, P. S., Nagarkatti, M., Prakash S. Nagarkatti   +11 more
core   +1 more source