Results 151 to 160 of about 1,621 (161)

Learning from stargazin: the mouse, the phenotype and the unexpected

Current Opinion in Neurobiology, 2006
The stargazin gene (also referred to as Cacng2) has been identified by forward genetics in a spontaneous mouse mutant with ataxic gait, upward head-elevating movements (hence the name stargazer for the mouse) and episodes of spike-wave discharges. Stargazin is related to the gamma-1 subunit of skeletal muscle voltage-dependent calcium channel (VDCC ...
Osten, P., Stern-Bach, Y.
openaire   +3 more sources

Stargazin mutation impairs cerebellar synaptogenesis, synaptic maturation and synaptic protein distribution

Brain Research, 2006
Stargazin mutation results in absence epilepsy and cerebellar ataxia in stargazer (stg) mice. We have previously discovered defects of AMPA receptor function, failure of BDNF expression and immature morphology specifically in the cerebellar cortex of stg mice.
Hongdi, Meng, Nicole, Walker, Yi, Su, Xiaoxi, Qiao   +3 more
openaire   +2 more sources

Dynamic Interaction of Stargazin-like TARPs with Cycling AMPA Receptors at Synapses

Science, 2004
Activity-dependent plasticity in the brain arises in part from changes in the number of synaptic AMPA receptors. Synaptic trafficking of AMPA receptors is controlled by stargazin and homologous transmembrane AMPA receptor regulatory proteins (TARPs). We found that TARPs were stable at the plasma membrane, whereas AMPA receptors were internalized in a ...
Susumu, Tomita, Masaki, Fukata, Roger A, Nicoll, David S, Bredt   +3 more
openaire   +2 more sources

Stargazin as a regulator of neuronal excitability

2023
Neuronal excitability refers to the ability of neurons to generate a change in membrane voltage in response to stimuli, and it is a fundamental characteristic of neurons at the basis of neuronal communication. The M-current is a low-threshold potassium current that determines neuronal excitability and contributes to dampening repetitive neuronal firing.
openaire   +1 more source

Crystal structure of the human Arc N-lobe bound to stargazin

, 2020
E. Hallin, C. Bramham, P. Kursula
semanticscholar   +1 more source

Faculty Opinions recommendation of A role for stargazin in experience-dependent plasticity.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2019
M. Kano, Takaki Watanabe
semanticscholar   +1 more source

Synaptic Stargazin

Science, 2006
openaire   +1 more source

Glutamate Receptor Clusters: Narp, EphB2 Receptor, Stargazin

2009
M.C. Chang, R.W. Cho, P.F. Worley
openaire   +1 more source

Inhibition of AMPA Receptors by Polyamine Toxins is Regulated by Agonist Efficacy and Stargazin

Neurochemical Research, 2014
M. H. Poulsen, S. Lucas, K. Strømgaard, A. Kristensen   +3 more
semanticscholar   +1 more source

Stargazin and gamma-4 slow the rate of channel opening and closing of GluA4 AMPA receptors

Vincen Pierce
semanticscholar   +1 more source