STAT3-EphA7 axis contributes to the progression of esophageal squamous cell carcinoma [PDF]
, 2023 Our previous study has revealed that EphA7 was upregulated in patient-derived esophageal squamous cell carcinoma (ESCC) xenografts with hyper-activated STAT3, but its mechanism was still unclear. To assess the association between EphA7 and STAT3, western
Xin Xu (11989) +10 more
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IL6-STAT3-HSP90 axis mediates temperature dependency of GCRV infection. [PDF]
, 2023 (A) Protein-protein interaction network of human STAT3 was analyzed online with the STRING database (http://string-db.org) under a ‘Creative Commons BY 4.0’ license (https://cn.string-db.org/cgi/access?footer_active_subpage=licensing).
Rui Song (331963) +13 more
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IL6-STAT3-HSP90 signaling axis mediates temperature dependency of GCRV infection. [PDF]
, 2023 (A) CIK cells transfected with different doses of STAT3-C plasmids were prepared to quantify the relative expression of IL6, IL1β, and TNF-α by RT-PCR analysis.
Rui Song (331963) +13 more
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IL6-STAT3-HSP90 axis mediates viral entry in aquatic ectotherms. [PDF]
, 2023 (A) Evolutionary conserveness analysis of STAT3 was conducted by multiple amino acids alignment of STAT3 from different species. The phosphorylation residue tyrosine 705 (Y705) which mediates the canonical STAT3 activation was highlighted in bold with ...
Rui Song (331963) +13 more
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Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway [PDF]
, 2003 Objective. Erythropoietin (EPO) is a key regulator of erythropoiesis, playing a role in both the proliferation and differentiation of erythroid cells.
Eggen, BJL +8 more
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Table_4_The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway.xlsx [PDF]
, 2022 Despite extensive research on Alzheimer’s disease (AD), its diagnosis and treatment remain challenging, and no effective therapies are currently available.
Shuo Huang (624671) +12 more
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Stat3 beta mitigates development of atherosclerosis in apolipoprotein E-deficient mice [PDF]
, 2014 The transcription factor Stat3 is an activator of systemic inflammatory genes. Two isoforms of Stat3 are generated by alternative splicing, Stat3 alpha and Stat3 beta.
李志元 +1 more
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Table_1_The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway.xlsx [PDF]
, 2022 Despite extensive research on Alzheimer’s disease (AD), its diagnosis and treatment remain challenging, and no effective therapies are currently available.
Shuo Huang (624671) +12 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2021 Background: Non-small cell lung cancer (NSCLC) is the most common malignancy worldwide. MiR-199a-5p has been reported to play important roles in multiple tumors, inclusive of NSCLC.
Xingping Yang +6 more
doaj +1 more source
Oxidative stress impairs multiple regulatory events to drive persistent cytokine-stimulated STAT3 phosphorylation [PDF]
, 2017 Although cytokine-driven STAT3 phosphorylation and activation are often transient, persistent activation of STAT3 is a hallmark of a range of pathologies and underpins altered transcriptional responses.
林琬琬 +1 more
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