Results 41 to 50 of about 216,448 (216)
Table_6_The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway.xlsx [PDF]
, 2022 Despite extensive research on Alzheimer’s disease (AD), its diagnosis and treatment remain challenging, and no effective therapies are currently available.
Shuo Huang (624671) +12 more
core +1 more source
T cell activation or tolerization: the Yin and Yang of bacterial superantigens
Frontiers in Microbiology, 2015 Bacterial superantigens are exotoxins from pathogens which interact with innate and adaptive immune cells. The paradox that superantigens cause activation and inactivation/anergy of T-cells was soon recognized.
Aline eSähr +3 more
doaj +1 more source
Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer [PDF]
, 2007 The main cause of prostate cancer-related mortality is the development of hormone-refractory disease. Circulating serum levels of IL-6 are raised in hormone-refractory prostate cancer patients and evidence from cell line studies suggests that the IL-6R ...
Tam, L. +11 more
core +1 more source
Table_5_The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway.xls [PDF]
, 2022 Despite extensive research on Alzheimer’s disease (AD), its diagnosis and treatment remain challenging, and no effective therapies are currently available.
Shuo Huang (624671) +12 more
core +1 more source
Frontiers in Neuroscience, 2013 In the mouse hypothalamus, ciliary neurotrophic factor (CNTF) is mainly expressed by ependymal cells and tanycytes of the ependymal layer covering the third ventricle.
Ilenia eSeveri +7 more
doaj +1 more source
Disease Models & Mechanisms, 2020 Colorectal cancer (CRC) is often accompanied by formation of liver metastases (LM) and skeletal muscle wasting, i.e. cachexia. Despite affecting the majority of CRC patients, cachexia remains underserved, understudied and uncured.
Joshua R. Huot +3 more
doaj +1 more source
Cancer Biology & Therapy, 2023 Daucosterol is a phytosterol glycoside with hepatoprotective properties. The objective of the present study was to confirm the role of daucosterol in liver failure. Exosomes were isolated from primary mouse umbilical cord mesenchymal stem cells (UCMSCs).
Changqing Deng +8 more
doaj +1 more source
STAT3 signaling in immunity [PDF]
Cytokine & Growth Factor Reviews, 2016 The transcriptional regulator STAT3 has key roles in vertebrate development and mature tissue function including control of inflammation and immunity. Mutations in human STAT3 associate with diseases such as immunodeficiency, autoimmunity and cancer.
Emily J. Hillmer +3 more
openaire +2 more sources
Differential silencing of STAT3 isoforms leads to changes in STAT3 activation
Oncotarget, 2023 Signal transducer and activator of transcription 3 (STAT3) is a transcription factor involved in multiple fundamental biological processes and a key player in cancer development and progression. STAT3 is activated upon tyrosine phosphorylation and is constitutively active in various malignancies; therefore, the expression of pSTAT3 has been recognized ...
Shamir, Inbal +3 more
openaire +2 more sources
Amino acid similarity of IL6-STAT3-HSP90 axis related proteins between species. [PDF]
, 2023 Amino acid similarity of IL6-STAT3-HSP90 axis related proteins between species.
Rui Song (331963) +13 more
core +1 more source