Results 241 to 250 of about 196,678 (325)

Procyanidin B2 3,3^″-di-O-gallate, a Biologically Active Constituent of Grape Seed Extract, Induces Apoptosis in Human Prostate Cancer Cells Via Targeting NF-κB, Stat3, and AP1 Transcription Factors

, 2013
Alpna Tyagi, Komal Raina, Suraj Prakash Shrestha, Bettina Miller, John A. Thompson, Michael F. Wempe, Rajesh Agarwal, Chapla Agarwal   +7 more
openalex   +2 more sources

Activating transcription factor 4 mediates hyperglycaemia-induced endothelial inflammation and retinal vascular leakage through activation of STAT3 in a mouse model of type 1 diabetes [PDF]

, 2012
Y. Chen, JoshuaJ Wang, J. Li, Ken‐ichi Hosoya, Rajiv R. Ratan, T M Townes, SarahX Zhang   +6 more
openalex   +1 more source

Dynamic Immune Cell Composition, Phenotypes, and Signaling in an Engineered Metastatic Niche

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In breast cancer patients, metastasis is the stage of disease where prognosis significantly worsens. However, the timing at which metastasis initiates and the location of metastatic lesions in an organ are stochastic, limiting the timely identification of disease and the administration of treatments.
Rebecca S. Pereles, Jyotirmoy Roy, Michael D. Brooks, Max S. Wicha, Jacqueline S. Jeruss, Lonnie D. Shea, Sophia M. Orbach   +6 more
wiley   +1 more source

Yin Yang 1 activates JAK-STAT3-mediated epithelial-mesenchymal transition in <i>Helicobacter pylori</i>-induced gastric cancer progression. [PDF]

World J Clin Oncol
Chen JW, Ouyang JJ, Wang ZH, Ma DM, Zhang Z, Teng Q, Yu G, Li XY.   +7 more
europepmc   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway. [PDF]

Mol Med Rep
Wu M, An Y, Li Y, He W, Wang Y, Wang Y, Wu C.   +6 more
europepmc   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

<i>Bacteroides fragilis</i> toxin in colorectal tumors activates STAT3 and drives microsatellite instability. [PDF]

Ann Med Surg (Lond)
Mehmood MS, Danaf N.
europepmc   +1 more source

Embryonic stem cells and nuclear transfer strategies - Present state and future prospects [PDF]

, 2000
Beier, Henning M., Wobus, Anna M., Wolf, Eckhard   +2 more
core   +1 more source

STAT3 Protein Interacts with Class O Forkhead Transcription Factors in the Cytoplasm and Regulates Nuclear/Cytoplasmic Localization of FoxO1 and FoxO3a Proteins in CD4+ T Cells

, 2012
Hyun‐Mee Oh, Cheng‐Rong Yu, Ivy M. Dambuza, Bernadette Marrero, Charles E. Egwuagu   +4 more
openalex   +1 more source