Results 281 to 290 of about 833,114 (323)

Keratinocytes regulate intraepithelial lymphocytes homing and mediate mucosal barrier integrity via JAK2/STAT3 signaling in oral lichen planus. [PDF]

Front Immunol
Zhou DY, Wang F, Bao CF, Zhou G.
europepmc   +1 more source

ARID1A deficiency activates OSM-STAT3 axis in endometrial cancer, creating vulnerability to JAK/STAT3 inhibition. [PDF]

Int J Biol Sci
Chen LJ, Shi C, Yang EJ, Ren G, Tao S, Pu Y, Zhang X, Shen X, Wu C, Shim JS.   +9 more
europepmc   +1 more source

Okadaic acid triggers NFκB and STAT3 phosphorylation followed by a release of inflammatory markers in human and mouse endothelial cells. [PDF]

Arch Toxicol
Nyback K, Alfonso A, Alvariño R, Suzuki T, Watanabe R, Uchida H, Vieytes MR, Botana LM.   +7 more
europepmc   +1 more source

Total flavonoids extracted from <i>Penthorum chinense Pursh</i> inhibits oxidative stress and inflammation in liver cancer cells through the JAK2/STAT3 pathway. [PDF]

Transl Cancer Res
Li X, Zhang X, Xue J.
europepmc   +1 more source

Chelidonine Induces Concurrent Elevation of pSer-STAT3 and Bcl-2 Levels in a Mitotic Subpopulation of Human T-Leukemia/Lymphoma Cells. [PDF]

Int J Mol Sci
Baddour S, Szöllősi J, Mátyus L, Vámosi G, Csomós I, Bodnár A.   +5 more
europepmc   +1 more source

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STAT3 transcription factor as target for anti-cancer therapy

Pharmacological Reports, 2020
STATs constitute a large family of transcription activators and transducers of signals that have an important role in many cell functions as regulation of proliferation and differentiation of the cell also regulation of apoptosis and angiogenesis. STAT3 as a member of that family, recently was discovered to have a vital role in progression of different
Aliaa M. Mohassab, Heba A. Hassan, Dalia Abdelhamid, Mohamed Abdel-Aziz   +3 more
semanticscholar   +4 more sources

Role of STAT3 Transcription Factor in Pathogenesis of Bronchial Asthma

Biochemistry (Moscow), 2021
Bronchial asthma is a heterogeneous chronic inflammatory disease of airways. The studies of molecular and cellular mechanisms of bronchial asthma have established that a wide range of immune (T and B cells, eosinophils, neutrophils, macrophages, etc.) and structural (epithelial and endothelial) cells are involved in its pathogenesis.
A. Nikolskii, I. Shilovskiy, E. Barvinskaia, A. Korneev, M. Sundukova, M. Khaitov   +5 more
semanticscholar   +3 more sources

Targeting transcription factor STAT3 for cancer prevention and therapy.

Pharmacology & Therapeutics, 2016
Signal Transducers and Activators of Transcription (STATs) comprise an important class of transcription factors that have been implicated in a wide variety of essential cellular functions related to proliferation, survival, and angiogenesis. Among various STAT members, STAT3 is frequently overexpressed in tumor cells as well as tissue samples, and ...
E. P. Z. Chai, M. Shanmugam, F. Arfuso, A. Dharmarajan, Chao Wang, A. Kumar, R. Samy, L. Lim, Lingzhi Wang, B. Goh, K. Ahn, K. Hui, G. Sethi   +12 more
semanticscholar   +4 more sources