Results 221 to 230 of about 4,534,601 (246)

The asthma-COPD overlap syndrome: Transcription factors GATA3 and STAT6 as possible markers

European Respiratory Journal, 2014
The aim of the study is to analyze an expression of transcription factors (GATA3, STAT6, et al.) and IFN-γ in peripheral blood of patients with asthma-COPD overlap syndrome and asthma. Materials and methods. 24 patients with asthma and 18 with asthma-COPD overlap syndrome were examined.
Lada Sorokina, Valeriy Mineev, Michail Nyoma, Valeria Lim, Anna Eremeeva, Vasiliy Ivanov, Vasiliy Trofimov   +6 more
openaire   +1 more source

The transcription factor BMAL1 inhibits endothelial cell apoptosis by targeting STAT6 to repress its expression

Cellular Signalling
Corneal transparency is critical for optimal visual function, and corneal neovascularization represents the primary cause of visual impairment globally. Recent studies have identified the transcription factor BMAL1 as a significant regulator of angiogenesis.
Qi, Yang, Ya'nan, Liang, Rui, Wang, Tongmei, Zhang, Ruiqing, Chai, Yiquan, Yan, Yateng, Tie, Yongchun, Wang, Xiqing, Sun, Yan, Cai, Xingcheng, Zhao   +10 more
openaire   +2 more sources

Treatment of cells with n-alpha-tosyl-l-phenylalanine-chloromethyl ketone induces the proteolytic loss of STAT6 transcription factor

Molecular Immunology, 2008
The implication of the STAT6 transcription factor in several human diseases makes the regulation of its activity a topic of great biological interest. The activation of this transcription factor is tightly regulated by kinases, phosphatases, and proteases.
Moises, Perez-G, Jose R, Cortes, Maria D, Rivas, F, Masa, Jose, Zamorano   +4 more
openaire   +2 more sources

In vivo expression of signal transducer and activator of transcription factor 6 (STAT6) in nasal mucosa from atopic allergic rhinitis: effect of topical corticosteroids

Clinical & Experimental Allergy, 2000
BackgroundThe allergen‐induced late nasal response is associated with a high local expression of interleukin (IL) ‐4, a TH2‐type cytokine implicated in immunoglobulin (Ig) E production, tissue eosinophilia and other events considered to be relevant to allergic inflammation.
O, Ghaffar, P, Christodoulopoulos, B, Lamkhioued, E, Wright, D, Ihaku, Y, Nakamura, S, Frenkiel, Q, Hamid   +7 more
openaire   +2 more sources

Silencing STAT6-Regulated Genes Through A Chimeric Transcription Factor

Journal of Allergy and Clinical Immunology, 2009
Y.H. Chyung, A.D. Luster
openaire   +1 more source

STAT5a/b BUT NOT STAT4 OR STAT6 TRANSCRIPTION FACTORS ARE CRITICAL FOR CD4+ CD25+ FUNCTION IN TRANSPLANTATION.

Transplantation, 2006
openaire   +1 more source

Signaling mechanisms, interaction partners, and target genes of STAT6

Cytokine and Growth Factor Reviews, 2006
Jutta Horejs-Hoeck, Albert Duschl
exaly  

The NADPH oxidase NOX4 and the transcription factor STAT6 as two key regulators of peripheral fat distribution in diet-induced obesity

Free Radical Biology and Medicine, 2022
openaire   +1 more source

Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II

EMBO Journal, 2002
Jie Yang, Marko Pesu, Olli Silvennoinen   +2 more
exaly  

STAT6 is amplified in a subset of dedifferentiated liposarcoma

Modern Pathology, 2014
Adrian Mariño-Enríquez
exaly