Results 11 to 20 of about 223,681 (205)
Patient‐Reported Reasons for Declining or Discontinuing Statin Therapy: Insights From the PALM Registry [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Many adults eligible for statin therapy for cardiovascular disease prevention are untreated. Our objective was to investigate patient‐reported reasons for statin underutilization, including noninitiation, refusal, and discontinuation.
Corey K. Bradley +10 more
doaj +3 more sources
The relationship between statin therapy and adipocytokine/inflammatory mediators in dyslipidemic nondiabetic patients: A comparative study [PDF]
Pharmacia, 2023 Background: Statins have emerged as a vital therapeutic option for dyslipidemia, effectively reducing morbidity and mortality in individuals with various medical conditions.
Hany A. Al-hussaniy +3 more
doaj +3 more sources
A multistate transition model for statin‐induced myopathy and statin discontinuation
CPT: Pharmacometrics & Systems Pharmacology, 2021 The overarching goal of this study was to simultaneously model the dynamic relationships among statin exposure, statin discontinuation, and potentially statin‐related myopathic outcomes.
Yuxi Zhu +9 more
doaj +1 more source
Statin use and cognitive function: population-based observational study with long-term follow-up. [PDF]
PLoS ONE, 2015 We aimed to evaluate the association between statin use and cognitive function. Cognitive function was measured with the Ruff Figural Fluency Test (RFFT; worst score, 0; best score, 175 points) and the Visual Association Test (VAT; low performance, 0-10;
Hanneke Joosten +6 more
doaj +1 more source
Impact of metformin on statin‐associated myopathy risks in dyslipidemia patients
Pharmacology Research & Perspectives, 2023 A growing number of patients with metabolic disorders are receiving statin and antidiabetic therapies as comedications. A signal of increased risk of myotoxicity due to potential interactions between antidiabetics and statins has been detected in ...
Keunhyeong Bak +4 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Whether statin use can reduce the risk of heart failure (HF) remains controversial. The present study evaluates the association between statin use and HF in patients with atrial fibrillation.
Jia‐Yi Huang +15 more
doaj +1 more source
Modest effect of statins on fasting glucose in a longitudinal electronic health record based cohort
Cardiovascular Diabetology, 2022 Background Prior studies of the glycemic effect of statins have been inconsistent. Also, most studies have only considered a short duration of statin use; the effect of long-term statin use on fasting glucose (FG) has not been well examined.
Tanushree Haldar +7 more
doaj +1 more source
The association of statin use after cancer diagnosis with survival in pancreatic cancer patients: a SEER-medicare analysis. [PDF]
, 2015 BackgroundPancreatic cancer has poor prognosis and existing interventions provide a modest benefit. Statin has anti-cancer properties that might enhance survival in pancreatic cancer patients.
Cook-Wiens, Galen +6 more
core +5 more sources
Life, 2023 (1) Background: Moderate-intensity statin therapy, when compared to high-intensity statin therapy in Asian populations, has shown no significant difference in cardiovascular prognosis in small studies.
Sang-Suk Choi +17 more
doaj +1 more source
PLoS ONE, 2022 Statin is highly recommended for dyslipidemia to prevent atherosclerosis-related cardiovascular diseases and death. The aim of this study was to compare the efficacies and safeties of low/moderate-intensity statin plus ezetimibe combination therapy vs ...
Young-Mi Ah +2 more
doaj +2 more sources