Results 11 to 20 of about 226,308 (303)

Statin use and the risk of hepatocellular carcinoma among patients with chronic hepatitis B: an emulated target trial using longitudinal nationwide population cohort data

BMC Gastroenterology, 2023
Background No randomized controlled trials have been completed to see whether statin can decrease hepatocellular carcinoma (HCC) risk in chronic hepatitis B (CHB) patients.
Dong Hyun Sinn, Danbee Kang, Yewan Park, Hyunsoo Kim, Yun Soo Hong, Juhee Cho, Geum-Youn Gwak   +6 more
doaj   +1 more source

Comparative safety and efficacy of low- or moderate-intensity statin plus ezetimibe combination therapy and high-intensity statin monotherapy: A meta-analysis of randomized controlled studies

PLoS ONE, 2022
Statin is highly recommended for dyslipidemia to prevent atherosclerosis-related cardiovascular diseases and death. The aim of this study was to compare the efficacies and safeties of low/moderate-intensity statin plus ezetimibe combination therapy vs ...
Young-Mi Ah, Minseob Jeong, Hye Duck Choi   +2 more
doaj   +2 more sources

National Assessment of Statin Therapy in Patients Hospitalized with Acute Myocardial Infarction: Insight from China PEACE-Retrospective AMI Study, 2001, 2006, 2011. [PDF]

PLoS ONE, 2016
BACKGROUND:Statin therapy is among the most effective treatments to improve short- and long-term mortality after acute myocardial infarction. The use of statin, and the intensity of their use, has not been described in acute myocardial infarction ...
Lihua Zhang, Jing Li, Xi Li, Khurram Nasir, Haibo Zhang, Yongjian Wu, Shuang Hu, Qing Wang, Nicholas S Downing, Nihar R Desai, Frederick A Masoudi, John A Spertus, Harlan M Krumholz, Lixin Jiang, China PEACE Collaborative Group   +14 more
doaj   +1 more source

Prescribing statin therapy in physically (in)active individuals vs prescribing physical activity in statin-treated patients: A four-scenario practical approach

Pharmacological Research, 2023
Statins are among the most commonly prescribed medications worldwide. Statin-associated muscle symptoms (SAMS) represent a frequent statin-related adverse effect associated with statin discontinuation and increased cardiovascular disease (CVD) events ...
Blanca Gavilán-Carrera, Alberto Soriano-Maldonado, Juan Diego Mediavilla-García, Carl J. Lavie, José Antonio Vargas-Hitos   +4 more
doaj   +1 more source

Geographic variation in statin use for complex acute myocardial infarction patients: evidence of effective care? [PDF]

, 2014
Reprinted with permission of publisher.BACKGROUND: Despite strong evidence to designate statin use for secondary prevention of cardiovascular disease (CVD) as "effective care," observational studies show that many patients with CVD do not receive statins.
Abd, Armitage, Armitage, Fang, Fang, Florentin, Golomb, Ickowicz, Law, Lee, Nallamothu, Nichols, Robinson, Robinson, Sathasivam, Thompson, Wallace   +16 more
core   +1 more source

Statin use and cognitive function: population-based observational study with long-term follow-up.

PLoS ONE, 2014
We aimed to evaluate the association between statin use and cognitive function. Cognitive function was measured with the Ruff Figural Fluency Test (RFFT; worst score, 0; best score, 175 points) and the Visual Association Test (VAT; low performance, 0-10;
Hanneke Joosten, Sipke T Visser, Marlise E van Eersel, Ron T Gansevoort, Henk J G Bilo, Joris P Slaets, Gerbrand J Izaks   +6 more
doaj   +1 more source

High-dose statin pretreatment decreases periprocedural myocardial infarction and cardiovascular events in patients undergoing elective percutaneous coronary intervention: a meta-analysis of twenty-four randomized controlled trials. [PDF]

PLoS ONE, 2014
BACKGROUND: Evidence suggests that high-dose statin pretreatment may reduce the risk of periprocedural myocardial infarction (PMI) and major adverse cardiac events (MACE) for certain patients; however, previous analyses have not considered patients with ...
Le Wang, Pingan Peng, Ou Zhang, Xiaohan Xu, Shiwei Yang, Yingxin Zhao, Yujie Zhou   +6 more
doaj   +1 more source

The Different Cardiovascular Outcomes Between Long-Term Efficacy of Hydrophilic and Lipophilic Statin Therapy in Both Asian Diabetic Sexes

Dose-Response, 2019
Purpose: To evaluate the long-term efficacy of hydrophilic and lipophilic statin therapy for cardiovascular outcomes in Asian diabetic patients. Method: Newly diagnosed cases of type 2 diabetes during the period from January 2000 to December 2011 were ...
Shang-Yi Li, Hsin-Hung Chen, Cheng-Li Lin, Su-Yin Yeh, Chia-Hung Kao   +4 more
doaj   +1 more source

Common Statin Intolerance Variants in ABCB1 and LILRB5 Show Synergistic Effects on Statin Response: An Observational Study Using Electronic Health Records

Frontiers in Genetics, 2021
Background: Statin intolerance impacts approximately 10% of statin users, with side effects ranging from mild myalgia to extreme intolerance resulting in myopathy and rhabdomyolysis.
Alaa’ Lutfi Melhem, Mehul Kumar Chourasia, Margherita Bigossi, Margherita Bigossi, Cyrielle Maroteau, Alasdair Taylor, Roberto Pola, Adem Y. Dawed, Aleksi Tornio, Aleksi Tornio, Colin N. A. Palmer, Moneeza K. Siddiqui   +11 more
doaj   +1 more source

Physicians' Experiences as Patients with Statin Side Effects: A Case Series. [PDF]

, 2017
Physicians are among those prescribed statins and therefore, subject to potential statin adverse effects (AEs). There is little information on the impact of statin AEs on physicians affected by them. We sought to assess the character and impact of statin
Golomb, Beatrice Alexandra, Koslik, Hayley J, Meskimen, Athena Hathaway   +2 more
core   +2 more sources