Results 11 to 20 of about 150,085 (313)
Archives of Medical ScienceIntroduction There is insufficient evidence in statin on the treatment of Staphylococcus aureus (SA) infection, we observe and analyze the clinical outcomes and antibiotic resistance of SA bloodstream infections in patients who received statins ...
Jianwei Su +4 more
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Beyond Lipid-Lowering: Effects of Statins on Cardiovascular and Cerebrovascular Diseases and Cancer
Pharmaceuticals, 2022 The 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, also known as statins, are administered as first-line therapy for hypercholesterolemia, both as primary and secondary prevention.
Yoichi Morofuji +6 more
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PROTECTIVE EFFECT OF QUERCETIN AGAINST STATINS INDUCED-HEPATOTOXICITY IN CELL LINE [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2020 Objective: Statins are the most prescribed lipid lowering agents and consequently they prevent obstructive cardiovascular events in the world. Severe adverse effects of statins, involving myopathy and hepatotoxicity, sometimes limit their usage as lipid ...
Mohamad Kamal
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F1000Research, 2021 Statins are one of the standard treatments to prevent cardiovascular events such as coronary artery disease and heart failure (HF). However, data on the use of statins to improve clinical outcomes in patients with established HF remains controversial. We
Chanavuth Kanitsoraphan +2 more
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Statins: a repurposed drug to fight cancer
Journal of Experimental & Clinical Cancer Research, 2021 As competitive HMG-CoA reductase (HMGCR) inhibitors, statins not only reduce cholesterol and improve cardiovascular risk, but also exhibit pleiotropic effects that are independent of their lipid-lowering effects. Among them, the anti-cancer properties of
Wen Jiang +4 more
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Ecotoxicology and Environmental Safety, 2022 Statins are prescribed widely as lipid-lowering agents. However, statins are associated with an increased harmful risk on public health and the ecosystem.
Ying Han +4 more
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Pharmaceuticals, 2022 In the field of drug repurposing, the use of statins for treating dyslipidemia is considered promising in ovarian cancer treatment based on epidemiological studies and basic research findings.
Yusuke Kobayashi +12 more
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Cardiotoxicity as a Possible Side Effect of Statins
Reviews in Cardiovascular Medicine, 2023 According to current views, statins have a wide range of beneficial effects (lipid and non-lipid) on the cardiovascular system, so they are one of the most commonly used drugs for the prevention and management of patients with cardiovascular diseases ...
Aleksey Chaulin
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STATINS AND THE RISK OF DIABETES MELLITUS
Рациональная фармакотерапия в кардиологии, 2015 Randomized controlled trials have clearly demonstrated the efficacy of statins in reduction of serum low density lipoprotein cholesterol level by 25-50% from the baseline.
O. M. Drapkina
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Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2021 The results from previous observational studies and clinical trials about the neuroprotective benefits of statins use for the prevention of dementia are contradictory. It is unclear whether the neuroprotective benefits are experienced in a specific group
Ching-Yuan Chang MS +3 more
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