Results 11 to 20 of about 254,908 (357)
Archives of Medical ScienceIntroduction There is insufficient evidence in statin on the treatment of Staphylococcus aureus (SA) infection, we observe and analyze the clinical outcomes and antibiotic resistance of SA bloodstream infections in patients who received statins ...
Jianwei Su +4 more
doaj +2 more sources
British medical journal, 2021 Objective To assess the associations between statins and adverse events in primary prevention of cardiovascular disease and to examine how the associations vary by type and dosage of statins. Design Systematic review and meta-analysis.
Ting Cai +10 more
semanticscholar +1 more source
Hydrophilic or Lipophilic Statins?
Frontiers in Cardiovascular Medicine, 2021 Drugs can be classified as hydrophilic or lipophilic depending on their ability to dissolve in water or in lipid-containing media. The predominantly lipophilic statins (simvastatin, fluvastatin, pitavastatin, lovastatin and atorvastatin) can easily enter
E. Climent, D. Benaiges, J. Pedro-Botet
semanticscholar +1 more source
Investigating the Effects of Statins on Cellular Lipid Metabolism Using a Yeast Expression System [PDF]
, 2009 In humans, defects in lipid metabolism are associated with a number of severe diseases such as atherosclerosis, obesity and type II diabetes. Hypercholesterolemia is a primary risk factor for coronary artery disease, the major cause of premature deaths
Zimnicka, Magdalena +29 more
core +3 more sources
STATINS AND THE RISK OF DIABETES MELLITUS
Рациональная фармакотерапия в кардиологии, 2015 Randomized controlled trials have clearly demonstrated the efficacy of statins in reduction of serum low density lipoprotein cholesterol level by 25-50% from the baseline.
O. M. Drapkina
doaj +3 more sources
Cardiotoxicity as a Possible Side Effect of Statins
Reviews in Cardiovascular Medicine, 2023 According to current views, statins have a wide range of beneficial effects (lipid and non-lipid) on the cardiovascular system, so they are one of the most commonly used drugs for the prevention and management of patients with cardiovascular diseases ...
Aleksey Chaulin
doaj +1 more source
Statins reduce new-onset atrial fibrillation after acute myocardial infarction
Medicine, 2020 Atrial fibrillation (AF) is an important complication of acute myocardial infarction (AMI). The association between AF and serum lipid profile is unclear and statin use for lowering the incidence of new-onset AF remains controversial.
Chien-Hao Tseng +7 more
semanticscholar +1 more source
Cell Metabolism, 2020 Summary Statins are lipid-lowering therapeutics with favorable anti-inflammatory profiles and have been proposed as an adjunct therapy for COVID-19. However, statins may increase the risk of SARS-CoV-2 viral entry by inducing ACE2 expression.
Xiao-Jing Zhang +48 more
semanticscholar +1 more source
Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2021 The results from previous observational studies and clinical trials about the neuroprotective benefits of statins use for the prevention of dementia are contradictory. It is unclear whether the neuroprotective benefits are experienced in a specific group
Ching-Yuan Chang MS +3 more
doaj +1 more source
Pharmaceuticals, 2022 In the field of drug repurposing, the use of statins for treating dyslipidemia is considered promising in ovarian cancer treatment based on epidemiological studies and basic research findings.
Yusuke Kobayashi +12 more
doaj +1 more source