Results 31 to 40 of about 254,908 (357)
Statins and cancers [PDF]
Współczesna Onkologia, 2015 Statins (inhibitors of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase) are a group of drugs used to treat lipid disorders. They inhibit cholesterol synthesis at an early stage of the biosynthesis pathway, thus eliminating numerous metabolites involved in the cycle.Stryjkowska-Góra, Aleksandra, Karczmarek-Borowska, Bożenna, Góra, Tomasz, Krawczak, Katarzyna +3 moreopenaire +2 more sourcesStatin Hepatotoxicity: Is it a Real Concern?
Heart Views, 2011 Statins are the most effective and widely used drugs for treating dyslipidemia, a major risk factor for coronary heart disease. These are one of the safest hypolipidemic drugs but many patients are advised to discontinue statins for the fear of ...Pranav Sikka, K K Saxena, Seema Kapoordoaj +1 more sourceEffect of statins on post-contrast acute kidney injury: a multicenter retrospective observational study
Lipids in Health and Disease, 2021 Background Post-contrast acute kidney injury (PC-AKI) is a severe complication of coronary angiography (CAG) and percutaneous coronary intervention (PCI). Currently, the effect of statins on PC-AKI and its mechanism remains unclear.Maoning Lin, Tian Xu, Wenjuan Zhang, Duannbin Li, Ya Li, Xulin Hong, Yi Luan, Wenbin Zhang, Min Wang +8 moredoaj +1 more sourceProspects for the use of statins in antiviral therapy [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2023 Inhibitors of hydroxymethylglutaryl-CoA reductase, in addition to suppressing cholesterol synthesis, have an antiviral effect. Clinical studies have shown antiviral efficacy of statins against COVID-19, HCV, HBV, RSV, HIV, influenza viruses.Mustafin R.N.doaj +1 more sourcePleiotropic effects of statins: a focus on cancer.
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020 The statin drugs ('statins') potently inhibit hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase by competitively blocking the active site of the enzyme.M. Ahmadi, Shayan Amiri, S. Pecić, Filip Machaj, Jakub Rosik, Marek J. Łos, Javad Alizadeh, R. Mahdian, Simone C. da Silva Rosa, D. Schaafsma, S. Shojaei, T. Madrakian, A. Zeki, S. Ghavami +13 moresemanticscholar +1 more sourcePharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins [PDF]
, 2014 Statins effectively lower LDL cholesterol levels in large studies and the observed interindividual response variability may be partially explained by genetic variation.Herrington, D.M., Postmus, Iris, Trompet, S., Ridker, P.M., O'Donnell, C.J. (Christopher J.), Ballantyne, C. (Christie), Liu, YM, Kastelein, JJP, Rivadeneira Ramirez, F. (Fernando), Pearson, Richard, Arnold, A.M. (Alice), O???donnell, Christopher J., Palmer, Colin N.A., Boerwinkle, E., Wei, W.-Q. (Wei-Qi), Barnes, M.R., Viswanathan, Ananth C., Potter, S.C. (Simon), Arnold, A.M., Caulfield, M. (Mark), Groop, L, Viswanathan, A.C. (Ananth), McKeigue, Paul M., Eiriksdottir, Gudny, Pirinen, M. (Matti), Palmer, Colin N. A., Barratt, BJ, Edkins, Sarah, Waller, Matthew, Smith, AV, Whitsel, E.A. (Eric), de Keyser, Catherine E., Buckley, BM, Arsenault, B.J. (Benoit J.), Whitsel, E.A., Hammond, Naomi, Sever, P, Franco Duran, OH, Liu, Y, Corvin, A. (Aiden), Palmer, CN, Barratt, B.J., Liu, Ching-Ti, Kastelein, J.J.P. (John), Groop, L., Macfadyen, JG, de Keyser, Toke, Zhou, Kaixin, Ford, I, Trompet, S. (Stella), Su, Zhan, Boerwinkle, Eric, Chu, A.Y., Sotoodehnia, Nona, Franco, O.H., Band, G. (Gavin), Wiggins, Kerri L., Eiriksdottir, G, O'Donnell, CJ, Chen, Y.-D. Ida, Boerwinkle, E, Uitterlinden, AG, Potter, Simon C., Heckbert, Susan R, Feng, Q. (Qiping), Hofman, A., Bis, JC, Krauss, Ronald M., Nickerson, D.A. (Deborah), Harris, T.B. (Tamara), Evans, DS, Palmer, C.N.A. (Colin), Blackburn, H. (Hannah), Stanton, A. (Alice), Wood, N.W. (Nicholas), Tardif, J-C, Wiggins, K.L. (Kerri), Johnson, A.D. (Andrew), Giulianini, F., Jukema, JW, Kritchevsky, S.B., Munroe, PB, Pierre Dubé, Marie, Cupples, L.A. (Adrienne), Blackwell, K.L. (Kimberly), Griffin, P., Keyser, C.E. de, Pirinen, Matti, Morris, A., Sattar, N, Rivadeneira, F, Griffin, P. (Paula), Shields, Denis C., Herrington, DM, Hellenthal, Garrett, Plomin, R. (Robert), Stafford, J.M. (Jeanette M.), Bellenguez, C??line, Betteridge, J, Shields, D.C., Widaa, S. (Sara), Stürmer, Til, Hitman, G, Wiggins, K.L., Bumpstead, Suzannah J., Hovingh, G.K., Neil, A. (Andrew), Tardif, J.-C. (Jean-Claude), Lumley, T., O'Brien, E. (Eoin), Munroe, P. (Patricia), ?, ?, de Craen, AJM, Liu, C-T, Wiggins, KL, Ford, Ian, De Craen, AJ, O’Donnell, Christopher J., Stafford, Jeanette M., Sotoodehnia, N. (Nona), McCarthy, MI, Bramon, E. (Elvira), Slagboom, PE, Casas, J.P. (Juan), Neil, Andrew, MacFadyen, J.G. (Jean G.), Shields, D.C. (Denis C.), Taylor, KD, Doney, A., Wei, Wei-Qi, Adrienne Cupples, L, Wilke, RA, Taylor, K.D., Strange, A. (Amy), Spencer, Chris C.A., McCann, O.T. (Owen), Morris, Andrew, Welcome Trust Case Control Consort, Postmus, D. (Douwe), Emilsson, V., Freeman, Colin, Launer, L.J., Guo, Xiuqing, Spencer, Chris C. A., Avery, C.L., Cupples, L.A., Rice, Kenneth, Krauss, RM, Gray, Emma, Chasman, Daniel I., Sever, P. (Peter), Caulfield, M.J., Li, G. (Guo), O'Brien, Eoin, Franco, OH, Gudnason, V. (Vilmundur), other, and, Sotoodehnia, N, Nickerson, D.A., Jayakumar, A. (Alagurevathi), Boekholdt, S.M., Chu, AY, Uitterlinden, Andr?? G., Wilke, R.A. (Russell A.), Doney, Alex; id_orcid, Li, XH, Sun, FG, Colhoun, HM, MacFadyen, J.G., Chasman, Daniel, Avery, CL, Rice, K., Betteridge, John, Carr, F, Durrington, P.N. (Paul), Ngwa, JS, Buckley, B.M., Post, Wendy, Deshmukh, H.A., Herrington, D.M. (David), Liu, C.-T. (Ching-Ti), Giulianini, F. (Franco), Munroe, Patricia B., Hammond, N. (Naomi), Uitterlinden, A.G. (André), Ahlqvist, E. (Emma), Ridker, PM, Jukema, J.W., Widaa, Sara, Betteridge, J., Duncanson, A. (Audrey), Ding, JZ (Jing Zhong), Adrienne Cupples, L., Sever, Peter, Poulter, N, Zhou, K. (Kaixin), Ballantyne, C.M., Matthijs Boekholdt, S., Carr, F., Liu, CT, Stott, D.J. (David. J.), Slagboom, P.E., Morris, A.D. (Andrew), Buckley, Brendan M., Mathew, C.G. (Christopher G.), Stanton, A, Gudnason, V, Li, Xiaohui, Shaw-Hawkins, S. (Sue), O???brien, Eoin, Ding, Jingzhong, Uitterlinden, André G., Cupples, LA, Nyberg, F, Mathew, Christopher G., Wellcome Trust Case Control Consortium, Warren, Helen R., Wei, WQ, Chu, A.Y. (Audrey), Warren, H.R., Stott, D.J., Smith, Albert V., Barratt, B.J. (Bryan J.), Westendorp, Rudi G. J., Vasan, Ramachandran S., Bramon, Elvira, Plomin, Robert, Nyberg, F. (Fredrik), Hellenthal, F.A., McCarthy, M.I., Tardif, Jean-Claude, Sawcer, S.J. (Stephen), Pierre Dub??, Marie, Chen, Y-DI, Munroe, P.B., Band, Gavin, Tardif, JC, Rotter, J.I., Post, W. (Wendy), Groop, L. (Leif), Wilke, R.A., Trompet, Stella, Psaty, B.M. (Bruce), Harris, TB, Casas, Juan P., Keyser, C.E. (Catherina Elisabeth) de, Stafford, JM, Deloukas, Panos, Li, X. (Xiaohui), Herrington, David M., Neil, A, Brown, Matthew, Ida Chen, Y.-D., Bellenguez, C. (Céline), Li, Guo, Barroso, Ines, Sun, F. (Fangui), McKeigue, P.M., Launer, Leonore J., Guo, XQ, Lumley, Thomas, Kastelein, John J. P., Chu, Audrey Y., Smith, Nicholas L., Smith, A.V. (Davey), Hofman, Albert, Donnelly, L.A. (Louise), Palmer, CNA, Barnes, M.J. (Michael), Doney, A, Tardif, J.C., Postmus, I, Shaw-Hawkins, S, de Craen, Anton J. M., Stricker, Bruno H., Poulter, N.R. (Neil), Stanton, A., Liddle, J. (Jennifer), Avery, Christy L., Vasan, R.S., Su, Z. (Zhan), Barroso, I.E. (Inês), Ding, J, Colhoun, H.M. (H.), Ngwa, Julius S., Ahlqvist, E, Corvin, Aiden, Rotter, J.I. (Jerome I.), Johnson, Andrew D., Rotter, JI, Ricketts, M. (Michelle), McCarthy, M.I. (Mark), Ahlqvist, Emma, Franco, O.H. (Oscar), Trembath, R.C. (Richard), Ballantyne, Christie M., Sotoodehnia, N., Psaty, Bruce M., Wei, W-Q, Carr, Fiona, Hitman, G.A. (Graham), Liu, C.T., Feng, Q, Barnes, Michael, Smith, N.L., Caulfield, Mark J., Westendorp, RGJ, MacFadyen, Jean G., Doney, Alex, Boekholdt, SM, Gudnason, V., Deshmukh, HA, Slagboom, P.E. (Eline), Boekholdt, S.M. (Matthijs), Freeman, C. (Colin), Neil, A., Stricker, Bruno, Barnes, Michael R., Liddle, Jennifer, Whittaker, Pamela, Bis, J.C. (Joshua), Ngwa, J.S., Chasman, D.I. (Daniel), Gwilliam, R. (Rhian), Durrington, Paul N., Hofman, Bert, Denny, J.C. (Joshua C.), Jukema, J. Wouter, Johnson, A.D., Trembath, Richard, Rautanen, A. (Anna), Liu, Y. (YongMei), Mathew, Christopher G.; id_orcid, Jankowski, J.A. (Janusz Antoni), Donnelly, LA, Gwilliam, Rhian, Palmer, C.N.A., Wood, Nicholas W., Dubé, MP, Heckbert, SR, Bellenguez, Céline, Sattar, Naveed, Giannoulatou, E. (Eleni), Stott, David J., Lumley, T, Franco, Oscar H., Durrington, P.N., Deshmukh, Harshal A., De Keyser, CE, Whitsel, EA, Ahlqvist, E., Waller, M. (Matthew), Smith, A.V., Uitterlinden, André, Heckbert, S.R. (Susan), Blackwell, Jenefer M., Kritchevsky, SB, Craen, A.J. (Anton) de, Mckeigue, P.M. (Paul), Chasman, DI, Bumpstead, S. (Suzannah), Dube, M.P., Boekholdt, S. Matthijs, Feng, QiPing, Guo, X.Q., Slagboom, P. Eline, Stuermer, T, Rivadeneira, Fernando, Brown, M.A. (Matthew), Stricker, B.H.Ch. (Bruno), Edkins, T. (Ted), Blackburn, Hannah, Eiriksdottir, G. (Gudny), Smith, N.L. (Nicholas), Bis, J.C., Ravindrarajah, Radhi, Harris, T.B., Smith, J.D. (Joshua D.), Rice, K.M. (Kenneth), Barnes, MR, Wilke, Russell A., Hitman, G., Feng, QP, McCann, Owen T., Ding, J.Z., Sawcer, Stephen J., Vukcevic, D. (Damjan), Jukema, J.W. (Jan Wouter), Wouter Jukema, J, Liu, Y.M., Hitman, Graham, Strange, Amy, Li, G, Hunt, S.E. (Sarah), Eline Slagboom, P., Ding, J. (Jingzhong), Langford, C. (Cordelia), St??rmer, Til, Langford, Cordelia, Stricker, B.H., Shaw-Hawkins, S., Kastelein, JJ, Donnelly, P. (Peter), Evans, Daniel S., Deshmukh, H. (Harshal), Betteridge, J. (John), Boerwinkle, E.A. (Eric), Eiriksdottir, G., Hovingh, G. Kees, Westendorp, R.G.J., Johnson, AD, Bis, Joshua C., McCarthy, Mark I., Denny, Joshua C., Dronov, Serge, Emilsson, V. (Valur), Harris, Tamara B., Li, X, Westendorp, R.G.J. (Rudi), Warren, HR, Giulianini, Franco, Guo, X. (Xiuqing), Emilsson, Valur, Heckbert, S.R., Weston, P. (Paul), Chen, Y.D.I., Kastelein, J.J.P., Launer, LJ (Lenore), Gudnason, Vilmundur, Dronov, S. (Serge), Post, W., Vasan, RS, Poulter, Neil, Chen, YDI, Uitterlinden, André; id_orcid, Sever, P., Rivadeneira, F., Liu, Yongmei, Stanton, Alice, Kastelein, John J.P., Sattar, N. (Naveed), Gillman, M. (Matthew), Craen, A.J.M. de, Donnelly, Peter, de Craen, Anton J.M., Shaw-Hawkins, Sue, Arsenault, BJ, Postmus, I., Durrington, PN, Griffin, P, Smith, Joshua D., Smith, JD, Rice, K, Dubé, G.P. (Gregory), Spencer, C.C.A. (Chris C.), Zhou, KX, Hovingh, G.K. (Kees), O’Brien, Eoin, Gillman, Matthew, Nickerson, DA, Arsenault, B.J., Donnelly, L.A., O'Donnell, C.J., Trembath, Richard C., Warren, H. (Helen), O'Brien, E., Hofman, A. (Albert), Denny, JC, Post, W, Sattar, N., Taylor, Kent D., Ford, I., Vukcevic, Damjan, Stürmer, T., Poulter, N., Caulfield, MJ, Guo, X, Weston, Paul, Whitsel, Eric A., Colhoun, Helen M., Donnelly, Louise A., Uitterlinden, A.G., Stott, DJ, Doney, A.S.F. (Alex), Rautanen, Anna, Buckley, B.M. (Brendan M.), Deshmukh, Harshal, Jankowski, Janusz, Colhoun, H.M., Ridker, P.M. (Paul), Nyberg, Fredrik, Vasan, R.S. (Ramachandran Srini), Dubé, Marie Pierre, Emilsson, V, Krauss, R.M. (Ronald), Feng, Q.P., Arnold, Alice M., Brown, Matthew A., Psaty, BM, Arsenault, Benoit J., Zhou, K, Whittaker, P. (Pamela), Westendorp, RG, Sun, Fangui, Chen, YD, Slagboom, PE (Eline), Smith, J.D., Kritchevsky, Stephen B., Consort, WTCC, Nickerson, Deborah A., Evans, D.S. (Daniel), Smith, NL, Chen, Y.-D.I. (Ida), Taylor, K.D. (Kent), Stafford, J.M., Psaty, B.M., Griffin, Paula, Giannoulatou, Eleni, Hofman, A, Carr, F. (Fiona), Nyberg, F., Lumley, T. (Thomas), Giulianini, F, Duncanson, Audrey, Launer, L.J. (Lenore), Markus, Hugh S., Hovingh, GK, Trompet, S, Stricker, BH, Li, X.H., Ballantyne, CM, Launer, LJ, Chasman, D.I., Li, G., Kees Hovingh, G., Markus, H.S. (Hugh), Evans, D.S., Morris, A, Sun, F, Krauss, R.M., McKeigue, PM, Wei, W.Q., Jayakumar, Alagurevathi, Groop, Leif, Rotter, Jerome I., Ricketts, Michelle, Kritchevsky, S.B. (Stephen), Gray, E. (Emma), Ravindrarajah, R. (Radhi), Shields, DC, Deloukas, P. (Panagiotis), Pearson, R. (Ruth), Sun, F.G., Zhou, K.X., Denny, J.C., Hunt, Sarah E., Barratt, Bryan J., Stürmer, T, Ridker, Paul M., O'Brien, E, Arnold, AM, Palmer, Colin N. A.; id_orcid, Vasan, Ramachandran S, Harris, Tamara B, McCarthy, Mark I, Uitterlinden, André G, Nyberg, Fredrik,, Whitsel, Eric A, Palmer, Colin NA, Warren, Helen R, Smith, Albert V, Stricker, Bruno H, MacFadyen, Jean G, Chu, Audrey Y, McKeigue, Paul M, Kastelein, John JP, Chasman, Daniel I, Denny, Joshua C, Wiggins, Kerri L, Ballantyne, Christie M, Launer, Leonore J, Avery, Christy L, Franco, Oscar H, de Craen, Anton J M, Rotter, Jerome I, Barnes, Michael R, Durrington, Paul N, Lund University., de Keyser, Catherine E, Kastelein, John J P, Colhoun, Helen M, Kees Hovingh, G, Ngwa, Julius S, Buckley, Brendan M, Johnson, Andrew D, Ahlqvist, Emma,, Stafford, Jeanette M, Munroe, Patricia B, Evans, Daniel S, Bis, Joshua C, Smith, Joshua D, Stott, David J, Deshmukh, Harshal A, Psaty, Bruce M, Westendorp, Rudi G J, Groop, Leif,, Donnelly, Louise A, Ida Chen, Y-D, Arnold, Alice M, Ridker, Paul M, Palmer, Colin N A, Smith, Nicholas L, Herrington, David M, Matthijs Boekholdt, S, Barratt, Bryan J, O'Donnell, Christopher J, O’Donnell, Christopher J, de Craen, Anton JM, Eline Slagboom, P, Kritchevsky, Stephen B, Shields, Denis C, Krauss, Ronald M, Nickerson, Deborah A, Westendorp, Rudi GJ, Arsenault, Benoit J, Caulfield, Mark J, Wilke, Russell A, Taylor, Kent D +627 morecore +2 more sourcesEffect of statins on venous thromboembolic events: a meta-analysis of published and unpublished evidence from randomised controlled trials [PDF]
, 2012 Background - It has been suggested that statins substantially reduce the risk of venous thromboembolic events. We sought to test this hypothesis by performing a meta-analysis of both published and unpublished results from randomised trials of statins.
Jacquet Hervet, Michel, Pieter Kamphuisen, Wikstrand John, Bhala, Neeraj, Haluska, B. A., Sara Biere-Rafi (135090), Kostner, K., Emberson, J, Hegney, D., Pieter Kamphuisen (135078), Bolte, J., McMurray, J.J.V., Delhaas, T., Holliday, J., Wikstrand, J, Glasziou, P. P., Hall, A. S., Samani, N. J., Emberson, J., Carrington, M. J., Blankenberg, S., Reino Maceiras, Maria Victoria, Ling, H. L., Álvarez Álvarez, Belén, Alvarez Castro, Ezequiel, Michele Robertson (135100), Sara Biere-Rafi, Agra Bermejo, Rosa Maria, McMurray, John, Kazem Rahimi (135073), Kamphuisen, P., Frueh, M., Kamphuisen, Pieter, McMurray, J., Schute, F., McMurray John, Biere-Rafi, Sara, Reha-Sleep-Registry, Paradela Dobarro, Beatriz, García Acuña, José María, Janousek, J., Robertson, Michele, Wikstrand, John, Abuassi, Emad, Robertson, M., Kamphuisen, P, Kamke, W., Robertson Michele, Michele Robertson, Zeller, T., Biere-Rafi Sara, Stewart, S., McMurray, J, Peña Gil, Carlos, Rodiño Janeiro, Bruno K, Musameh, M. D., John McMurray, Wang, W. Y. S., Emberson Jonathan, S. Caravita, A. Faini, Neeraj Bhala (135075), John Wikstrand, John McMurray (135109), Keech, A. C., Vera Krane (135094), Jonathan Emberson, Van Geldorp, I., Jonathan Emberson (135084), Rahimi, Kazem, Tonkin, A. M., Elders, J., Rahimi, K, Schroeder, K., S. Salerno, Krane Vera, Krane, V, Vera Krane, Sullivan, D. R., Wikstrand, John,, Bhala, N., Prinzen, F. W., Nelson, C. P., E. Lisi, Krane, V., Biere-Rafi, S., Alt, B., Neeraj Bhala, Skobel, E., Grigorian Shamagian, Lilian, Ball, S. G., G. Parati, Biere-Rafi, S, Kazem Rahimi, ?, ?, Balmforth, A. J., Tomaszewski, M., M. Valentini, John Wikstrand (135105), White, H. D., Carrington, M., Schwaab, B., Rosenthal, E., Raposeiras Roubín, Sergio, Gestal Romani, Santiago, Bhala Neeraj, Cabanas Grandio, Maria Pilar, Emberson, Jonathan, Woehrle, H., Kamphuisen Pieter, Espinoza, D., Tomaske, M., Bhala, N, Hague, W., Rahimi Kazem, G. Bilo, Krane, Vera, P. Agostoni, Rahimi, K., Haluska, B., Krupickova, S., González Juanatey, José Ramón, González Cambeiro, María Cristina, Marwick, T. H., Wikstrand, J., Hiippala, A., Pereira Lopez, Eva Maria, Aguiar Souto, Pablo, Purucker, H. C., Boenner, G., Krüger, S., M. Revera, Simes, R. J., C. Lombardi, Robertson, M +134 morecore +2 more sources
