Results 81 to 90 of about 1,264 (145)

Biomedical Implications of Autophagy in Macromolecule Storage Disorders [PDF]

, 2019
An imbalance between the production and clearance of macromolecules such as proteins, lipids and carbohydrates can lead to a category of diseases broadly known as macromolecule storage disorders.
Dimova, Simona, Hoque, Sheabul, Palhegyi, Adina Maria, Sarkar, Sovan, Seranova, Elena   +4 more
core   +1 more source

Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism.

Journal of Biological Chemistry, 2011
Sixin Jiang, Brigitte Heller, Vincent S. Tagliabracci, Lanmin Zhai, Jose M. Irimia, Anna A. DePaoli-Roach, Clark D. Wells, Alexander V. Skurat, and Peter J.
Sixin Jiang, Brigitte L. Heller, V. Tagliabracci, L. Zhai, José M. Irimia, A. DePaoli-Roach, C. Wells, A. V. Skurat, P. Roach   +8 more
semanticscholar   +1 more source

Autophagy in healthy aging and disease [PDF]

, 2021
Autophagy is a fundamental cellular process that eliminates molecules and subcellular elements, including nucleic acids, proteins, lipids and organelles, via lysosome-mediated degradation to promote homeostasis, differentiation, development and survival.
Aman, Y, Bjedov, I, Fang, EF, Hansen, M, Johansen, T, Kroemer, G, Labbadia, J, Morimoto, RI, Palikaras, K, Partridge, L, Rubinsztein, DC, Schmauck-Medina, T, Simon, AK, Simonsen, A, Tavernarakis, N   +14 more
core  

Cargo Hitchhiking Autophagy - A Hybrid Autophagy Pathway Utilized in Yeast [PDF]

Macroautophagy is a catabolic process that maintains cellular homeostasis by recycling intracellular material through the use of double-membrane vesicles called autophagosomes. In turn, autophagosomes fuse with vacuoles (in yeast and plants) or lysosomes
Cooper, Katrina F
core   +2 more sources

Lysosomal glucose sensing and glycophagy in metabolism. [PDF]

Trends Endocrinol Metab, 2023
Mancini MC, Noland RC, Collier JJ, Burke SJ, Stadler K, Heden TD.   +5 more
europepmc   +1 more source

BIOCHEMICAL APPROACHES FOR THE DIAGNOSIS AND TREATMENT OF LAFORA DISEASE [PDF]

, 2019
Glycogen is the sole carbohydrate storage molecule found in mammalian cells and plays an important role in cellular metabolism in nearly all tissues, including the brain.
Brewer, Mary Kathryn
core   +1 more source

Glycogen-autophagy: Molecular machinery and cellular mechanisms of glycophagy. [PDF]

J Biol Chem, 2022
Koutsifeli P, Varma U, Daniels LJ, Annandale M, Li X, Neale JPH, Hayes S, Weeks KL, James S, Delbridge LMD, Mellor KM.   +10 more
europepmc   +1 more source

Aryl hydrocarbon receptor sulfenylation promotes glycogenolysis and rescues cancer chemoresistance. [PDF]

J Clin Invest, 2023
Zhou N, Chen J, Ling Z, Zhang C, Zhou Y, Wang D, Zhou L, Wang Z, Sun N, Wang X, Zhang H, Tang K, Ma J, Lv J, Huang B.   +14 more
europepmc   +1 more source

Mouse Stbd1 is N-myristoylated and affects ER–mitochondria association and mitochondrial morphology

Mouse Stbd1 is N-myristoylated and affects ER–mitochondria association and mitochondrial morphology
Starch binding domain-containing protein 1 (Stbd1) is a carbohydrate-binding protein that has been proposed to be a selective autophagy receptor for glycogen. Here, we show that mouse Stbd1 is a transmembrane endoplasmic reticulum (ER)-resident protein with the capacity to induce the formation of organized ER structures in HeLa cells.
openaire  

Osteocalcin modulates hippocampal activities and influences glycophagy within astrocytes in a chronic unpredictable mild stress mouse model. [PDF]

Compr Psychoneuroendocrinol
Chen H, Mao J, Wang M, Zhang Q, Zheng R, Wu Y, Ma X, Liu Q.   +7 more
europepmc   +1 more source