Results 21 to 30 of about 137,068 (205)

Non-alcoholic fatty liver disease: Definition and subtypes [PDF]

Clinical and Molecular Hepatology, 2023
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide, with a global prevalence of approximately 30%. However, the prevalence of NAFLD has been variously reported depending on the comorbidities.
Seul Ki Han, Soon Koo Baik, Moon Young Kim   +2 more
doaj   +1 more source

Similar reduction of cholesterol-adjusted Vitamin E serum levels in simple steatosis and non-alcoholic steatohepatitis [PDF]

, 2015
OBJECTIVES: Reduced vitamin E levels have been reported in patients with non-alcoholic steatohepatitis (NASH), but no conclusive data on patients with simple steatosis (SS) are available. Aim of this study was to investigate the association betweenserum
Angelico, Francesco, Baratta, Francesco, Bucci, Tommaso, Cangemi, Roberto, Carnevale, Roberto, DEL BEN, Maria, Labbadia, Giancarlo, Nocella, Cristina, Pani, Arianna, Pastori, Daniele, Pignatelli, Pasquale, Polimeni, Licia, Scardella, Laura, Violi, Francesco   +13 more
core   +1 more source

Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis. [PDF]

, 2015
Palmitic acid (PA) induces hepatocyte apoptosis and fuels de novo ceramide synthesis in the endoplasmic reticulum (ER). Myristic acid (MA), a free fatty acid highly abundant in copra/palmist oils, is a predictor of nonalcoholic steatohepatitis (NASH) and
Alarcón-Vila, C, Baulies, A, Caballeria, J, Casas, J, Elena, M, Fabriàs, G, Fernandez-Checa, JC, García-Ruiz, C, Martinez Gili, L, Torres, S   +9 more
core   +5 more sources

Longitudinal assessment of high blood pressure in children with nonalcoholic fatty liver disease. [PDF]

, 2014
ObjectiveNonalcoholic fatty liver disease (NAFLD) affects 9.6% of children and may put these children at elevated risk of high blood pressure and subsequent cardiovascular morbidity and mortality.
Behling, Cynthia, Donithan, Michele, Hallinan, Erin K, Newton, Kimberly P, Nonalcoholic Steatohepatitis Clinical Research Network, Schwimmer, Jeffrey B, Tonascia, James, Xanthakos, Stavra A, Zepeda, Anne   +8 more
core   +6 more sources

Integration analysis identifies the role of metallothionein in the progression from hepatic steatosis to steatohepatitis

Frontiers in Endocrinology, 2022
BackgroundNon-alcoholic fatty liver disease (NAFLD), a metabolic disorder that develops from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH), has become an epidemic of chronic liver dysfunction worldwide. However, mechanisms that
Xiaoya Li, Shaoping Zhong, Yifan Sun, Xinmei Huang, Yue Li, Lihong Wang, Yueyue Wu, Min Yang, Hai-Xin Yuan, Jun Liu, Shufei Zang   +10 more
doaj   +1 more source

The Benefit of Sleeve Gastrectomy in Obese Adolescents on Nonalcoholic Steatohepatitis and Hepatic Fibrosis [PDF]

, 2017
Objective To determine whether bariatric surgery is effective for the treatment of nonalcoholic steatohepatitis (NASH) in adolescence, we compared the efficacy of laparoscopic sleeve gastrectomy (LSG) with that of lifestyle intervention (nonsurgical ...
Alisi, Anna, Baumann, Ulrich, Caccamo, Romina, Cutrera, Renato, De Peppo, Francesco, De Stefanis, Cristiano, Giordano, Ugo, Manco, Melania, Mosca, Antonella, Nobili, Valerio, Silecchia, Gianfranco   +10 more
core   +1 more source

Obeticholic acid and ferrostatin-1 differentially ameliorate non-alcoholic steatohepatitis in AMLN diet-fed ob/ob mice

Frontiers in Pharmacology, 2022
Introduction: Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are common chronic liver diseases with limited treatment options.Methods: Ob/ob mice (6 weeks old) were fed with the Control diet or amylin liver NASH (AMLN)
Shengjie Li, Aoxiang Zhuge, Kaicen Wang, Jiafeng Xia, Qiangqiang Wang, Shengyi Han, Jian Shen, Lanjuan Li, Lanjuan Li   +8 more
doaj   +1 more source

Oxidative stress: new insights on the association of nonalcoholic fatty liver disease and atherosclerosis [PDF]

, 2015
Non-alcoholic fatty liver disease (NAFLD) represents the most common and emerging chronic liver disease worldwide. It includes a wide spectrum of liver diseases ranging from simple fatty liver to non-alcoholic steatohepatitis (NASH), which may progress ...
Albanese, Fabiana, Angelico, Francesco, Baratta, Francesco, DEL BEN, Maria, Pastori, Daniele, Perri, Ludovica, Polimeni, Licia, Violi, Francesco   +7 more
core   +1 more source

Genetic predictors and pathophysiological features of non-alcoholic fat liver disease

Медицинский совет, 2021
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of liver disease in highly developed countries. The risk of developing NAFLD and associated complications varies greatly among people of different nationalities and is determined by ...
O. V. Smirnova, O. L. Moskalenko, E. V. Kasparov, I. E. Kasparova,   +3 more
doaj   +1 more source

Repurposing drugs to target nonalcoholic steatohepatitis [PDF]

, 2019
Nonalcoholic fatty liver disease (NAFLD) is a complex disorder that has evolved in recent years as the leading global cause of chronic liver damage.
Pirola, Carlos José, Sookoian, Silvia Cristina   +1 more
core   +1 more source