Results 101 to 110 of about 110,517 (296)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Measuring the Conditional Luminosity and Stellar Mass Functions of Galaxies by Combining the Dark Energy Spectroscopic Instrument Legacy Imaging Surveys Data Release 9, Survey Validation 3, and Year 1 Data

The Astrophysical Journal
In this investigation, we leverage the combination of the Dark Energy Spectroscopic Instrument (DESI) Legacy Imaging Surveys Data Release 9, Survey Validation 3, and Year 1 data sets to estimate the conditional luminosity functions and conditional ...
Yirong Wang, Xiaohu Yang, Yizhou Gu, Xiaoju Xu, Haojie Xu, Yuyu Wang, Antonios Katsianis, Jiaxin Han, Min He, Yunliang Zheng, Qingyang Li, Yaru Wang, Wensheng Hong, Jiaqi Wang, Zhenlin Tan, Hu Zou, Johannes Ulf Lange, ChangHoon Hahn, Peter Behroozi, Jessica Nicole Aguilar, Steven Ahlen, David Brooks, Todd Claybaugh, Shaun Cole, Axel de la Macorra, Biprateep Dey, Peter Doel, Jaime E. Forero-Romero, Klaus Honscheid, Robert Kehoe, Theodore Kisner, Andrew Lambert, Marc Manera, Aaron Meisner, Ramon Miquel, John Moustakas, Jundan Nie, Claire Poppett, Mehdi Rezaie, Graziano Rossi, Eusebio Sanchez, Michael Schubnell, Gregory Tarlé, Benjamin Alan Weaver, Zhimin Zhou   +44 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Constraints on the Galaxy Formation Models during the Epoch of Reionization with High-redshift Observations

The Astrophysical Journal
We use high-resolution N -body dark matter simulations and L-G alaxies semianalytical galaxy formation models to explore the high- z galaxy properties and estimate the budget of ionizing photons.
Qing-Bo Ma, Xiao-Rong Chen, Ming Li, Qi Guo, Benedetta Ciardi, Anshuman Acharya, Xin Wang   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Surprisingly Similar: The Mass Function of Gaia Neutron Stars and Firstborn Double Neutron Stars

The Astrophysical Journal Letters
The mass distribution of neutron stars (NSs) encodes information about their formation and binary evolution. We compare the masses of two distinct populations: (I) the recently identified Gaia NSs in wide orbits with solar-like companions and (II) the ...
Aryanna Schiebelbein-Zwack, L. A. C. van Son, Maya Fishbach, Will M. Farr   +3 more
doaj   +1 more source

On the function describing the stellar initial mass function [PDF]

Monthly Notices of the Royal Astronomical Society, 2012
We propose a functional form for the IMF, the L_3 IMF, which is a natural heavy-tailed approximation to the log-normal distribution. It is composed of a low-mass power law and a high mass power-law which are smoothly joined together. Three parameters are needed to achieve this.
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Constraining Scatter in the Stellar Mass--Halo Mass Relation for Haloes Less Massive than the Milky Way

, 2019
Most galaxies are hosted by massive, invisible dark matter haloes, yet little is known about the scatter in the stellar mass--halo mass relation for galaxies with host halo masses $M_{h}\le 10^{11}M_{\odot}$.
Allen, Magdelena, Behroozi, Peter, Ma, Chung-Pei   +2 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source