Results 111 to 120 of about 110,517 (296)
The Astrophysical JournalThe abundance patterns of extremely metal-poor stars preserve a fossil record of the Universe’s earliest chemical enrichment by the supernova explosions from the evolution of first generation of stars, also referred to as Population III stars.
Ruizheng Jiang +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
On the Determination of Stellar Mass and Binary Fraction of Open Clusters within 500 pc from the Sun
The Astrophysical JournalWe investigated the stellar mass function and the binary fraction of 114 nearby open clusters (OCs) using the high-precision photometric data from Gaia Data Release 3 (Gaia DR3).
Yueyue Jiang +5 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
The Astrophysical Journal LettersWe construct the z = 0 galaxy stellar mass function (GSMF) by combining the GSMF at stellar masses M _* ≲ 10 ^11.3 M _⊙ from the census study of Leja et al.
Emily R. Liepold, Chung-Pei Ma
doaj +1 more source
Ages, Distances, and the Initial Mass Functions of Stellar Clusters [PDF]
, 2000 We provide a review of the current status of several topics on the ages, distances, and mass functions of open clusters, with a particular emphasis on illuminating the areas of uncertainty.
Jeffries, R. D. +3 more
core +2 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
An Integrated Picture of Star Formation, Metallicity Evolution, and Galactic Stellar Mass Assembly
, 2008 We present an integrated study of star formation and galactic stellar mass assembly from z=0.05-1.5 and galactic metallicity evolution from z=0.05-0.9 using a very large and highly spectroscopically complete sample selected by rest-frame NIR bolometric ...
A. J. Barger +4 more
core +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
The Assembly of Supermassive Black Holes at z < 1 in Early-type Galaxies from Scaling Relations
The Astrophysical JournalThe assembly of supermassive black hole (SMBH) mass ( M _• ) and stellar mass ( M _* ) in galaxies can be studied via the redshift evolution of the M _• – M _* relation, but the ways in which selection bias and physical assembly channels affect this ...
D. Farrah +16 more
doaj +1 more source