Results 11 to 20 of about 71,280 (265)

A Transcriptional Sequencing Analysis of Islet Stellate Cell and Pancreatic Stellate Cell [PDF]

open access: yesJournal of Diabetes Research, 2018
Background. Our previous studies have shown that islet stellate cell (ISC), similar to pancreatic stellate cell (PSC) in phenotype and biological characters, may be responsible for the islet fibrosis in type 2 diabetes.
Xiaohang Wang   +12 more
doaj   +3 more sources

Hepatic Stellate Cells and Hepatocarcinogenesis [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2020
Hepatic stellate cells (HSCs) are a significant component of the hepatocellular carcinoma (HCC) tumor microenvironment (TME). Activated HSCs transform into myofibroblast-like cells to promote fibrosis in response to liver injury or chronic inflammation, leading to cirrhosis and HCC.
Anna E. Barry   +12 more
openaire   +3 more sources

β-arrestin1 activates hepatic stellate cells to promote liver fibrosis via activating p38 signaling pathway [PDF]

open access: yesXin yixue, 2023
Objective To investigate the role ofβ-arrestin1 (ARRB1) in liver fibrosis and elucidate the mechanism of hepatic stellate cell activation induced by ARRB1/p38 signaling pathway to promote liver fibrosis.
Xia Yanhao, Liu Huiling, Jiang Jie, Wu Bin
doaj   +1 more source

Shedding light on stellate cells [PDF]

open access: yeseLife, 2018
The relationship between grid cells and two types of neurons found in the medial entorhinal cortex has been clarified.
Andrew S Alexander, Michael E Hasselmo
openaire   +3 more sources

Functional properties of stellate cells in medial entorhinal cortex layer II

open access: yeseLife, 2018
Layer II of the medial entorhinal cortex (MEC) contains two principal cell types: pyramidal cells and stellate cells. Accumulating evidence suggests that these two cell types have distinct molecular profiles, physiological properties, and connectivity ...
David C Rowland   +6 more
doaj   +1 more source

Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma

open access: yeseLife, 2020
Hepatocellular carcinoma (HCC) is a liver tumor that usually arises in patients with cirrhosis. Hepatic stellate cells are key players in the progression of HCC, as they create a fibrotic micro-environment and produce growth factors and cytokines that ...
Nataša Pavlović   +6 more
doaj   +1 more source

Hepatic Stellate Cells Support Hematopoiesis and are Liver-Resident Mesenchymal Stem Cells

open access: yesCellular Physiology and Biochemistry, 2013
Background/Aims: Hematopoiesis can occur in the liver, when the bone marrow fails to provide an adequate environment for hematopoietic stem cells.
Claus Kordes   +3 more
doaj   +1 more source

Seven Steps to Stellate Cells [PDF]

open access: yesJournal of Visualized Experiments, 2011
Hepatic stellate cells are liver-resident cells of star-like morphology and are located in the space of Disse between liver sinusoidal endothelial cells and hepatocytes(1,2). Stellate cells are derived from bone marrow precursors and store up to 80% of the total body vitamin A(1, 2).
Patrick, Maschmeyer   +2 more
openaire   +2 more sources

Extracellular Vesicles from Steatotic Hepatocytes Provoke Pro-Fibrotic Responses in Cultured Stellate Cells

open access: yesBiomolecules, 2022
Hepatic steatosis and chronic hepatocyte damage ultimately lead to liver fibrosis. Key pathophysiological steps are the activation and transdifferentiation of hepatic stellate cells.
Maria Teresa Koenen   +10 more
doaj   +1 more source

Bergmann glia and the recognition molecule CHL1 organize GABAergic axons and direct innervation of Purkinje cell dendrites.

open access: yesPLoS Biology, 2008
The geometric and subcellular organization of axon arbors distributes and regulates electrical signaling in neurons and networks, but the underlying mechanisms have remained elusive.
Fabrice Ango   +5 more
doaj   +1 more source

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