Results 11 to 20 of about 68,538 (266)

A Transcriptional Sequencing Analysis of Islet Stellate Cell and Pancreatic Stellate Cell [PDF]

Journal of Diabetes Research, 2018
Background. Our previous studies have shown that islet stellate cell (ISC), similar to pancreatic stellate cell (PSC) in phenotype and biological characters, may be responsible for the islet fibrosis in type 2 diabetes.
Xiaohang Wang, Wei Li, Juan Chen, Sheng Zhao, Shanhu Qiu, Han Yin, Vladmir Carvalho, Yunting Zhou, Ruifeng Shi, Jiannan Hu, Shenyi Li, Munire Nijiati, Zilin Sun   +12 more
doaj   +3 more sources

Hepatic Stellate Cells and Hepatocarcinogenesis [PDF]

Frontiers in Cell and Developmental Biology, 2020
Hepatic stellate cells (HSCs) are a significant component of the hepatocellular carcinoma (HCC) tumor microenvironment (TME). Activated HSCs transform into myofibroblast-like cells to promote fibrosis in response to liver injury or chronic inflammation, leading to cirrhosis and HCC.
Anna E. Barry, Anna E. Barry, Rajkumar Baldeosingh, Rajkumar Baldeosingh, Ryan Lamm, Keyur Patel, Kai Zhang, Kai Zhang, Dana A. Dominguez, Kayla J. Kirton, Ashesh P. Shah, Hien Dang, Hien Dang   +12 more
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Shedding light on stellate cells [PDF]

eLife, 2018
The relationship between grid cells and two types of neurons found in the medial entorhinal cortex has been clarified.
Andrew S Alexander, Michael E Hasselmo
openaire   +3 more sources

Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma

eLife, 2020
Hepatocellular carcinoma (HCC) is a liver tumor that usually arises in patients with cirrhosis. Hepatic stellate cells are key players in the progression of HCC, as they create a fibrotic micro-environment and produce growth factors and cytokines that ...
Nataša Pavlović, Carlemi Calitz, Kess Thanapirom, Guiseppe Mazza, Krista Rombouts, Pär Gerwins, Femke Heindryckx   +6 more
doaj   +1 more source

Excitatory granule neuron precursors orchestrate laminar localization and differentiation of cerebellar inhibitory interneuron subtypes

Cell Reports, 2021
Summary: GABAergic interneurons migrate long distances through stereotyped migration programs toward specific laminar positions. During their migration, GABAergic interneurons are morphologically alike but then differentiate into a rich array of ...
Christelle Cadilhac, Isabelle Bachy, Antoine Forget, David J. Hodson, Céline Jahannault-Talignani, Andrew J. Furley, Olivier Ayrault, Patrice Mollard, Constantino Sotelo, Fabrice Ango   +9 more
doaj   +1 more source

Hepatic Stellate Cells Support Hematopoiesis and are Liver-Resident Mesenchymal Stem Cells

Cellular Physiology and Biochemistry, 2013
Background/Aims: Hematopoiesis can occur in the liver, when the bone marrow fails to provide an adequate environment for hematopoietic stem cells.
Claus Kordes, Iris Sawitza, Silke Götze, Dieter Häussinger   +3 more
doaj   +1 more source

Seven Steps to Stellate Cells [PDF]

Journal of Visualized Experiments, 2011
Hepatic stellate cells are liver-resident cells of star-like morphology and are located in the space of Disse between liver sinusoidal endothelial cells and hepatocytes(1,2). Stellate cells are derived from bone marrow precursors and store up to 80% of the total body vitamin A(1, 2).
Patrick, Maschmeyer, Melanie, Flach, Florian, Winau   +2 more
openaire   +2 more sources

Purinergic Signaling in Liver Pathophysiology

Frontiers in Endocrinology, 2021
Extracellular nucleosides and nucleotides activate a group of G protein-coupled receptors (GPCRs) known as purinergic receptors, comprising adenosine and P2Y receptors. Furthermore, purinergic P2X ion channels are activated by ATP.
Shanu Jain, Kenneth A. Jacobson
doaj   +1 more source

Bergmann glia and the recognition molecule CHL1 organize GABAergic axons and direct innervation of Purkinje cell dendrites.

PLoS Biology, 2008
The geometric and subcellular organization of axon arbors distributes and regulates electrical signaling in neurons and networks, but the underlying mechanisms have remained elusive.
Fabrice Ango, Caizhi Wu, Johannes J Van der Want, Priscilla Wu, Melitta Schachner, Z Josh Huang   +5 more
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Storage of vitamin A in extrahepatic stellate cells in normal rats

Journal of Lipid Research, 1997
In mammals, vitamin A is primarily stored as retinyl esters in hepatic stellate cells under normal dietary intake of the vitamin. Previously, extrahepatic vitamin A-storing stellate cells have only been identified in animals maintained on a vitamin A ...
N E Nagy, K B Holven, N Roos, H Senoo, N Kojima, K R Norum, R Blomhoff   +6 more
doaj   +1 more source