Results 21 to 30 of about 68,538 (266)
Molecular Cancer, 2010 Background Tissue fibrosis is an integral component of chronic inflammatory (liver and pancreas) diseases and pancreatic cancer. Activated pancreatic- (PSC) and hepatic- (HSC) stellate cells play a key role in fibrogenesis. To identify organ- and disease-
Huber Peter E +13 more
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Hepatic stellate cell progenitor cells [PDF]
Journal of Gastroenterology and Hepatology, 2012 AbstractHepatic stellate cells (HSCs) are recognized as a major player in liver fibrogenesis. Upon liver injury, HSCs differentiate into myofibroblasts and participate in progression of fibrosis and cirrhosis. Additional cell types such as resident liver fibroblasts/myofibroblasts or bone marrow cells are also known to generate myofibroblasts.
openaire +2 more sources
BMC Cell Biology, 2002 Background Liver fibrosis is the common sequel of chronic liver diseases. Recent studies have identified hepatic stellate cells as the primary cell type mediating hepatic fibrogenesis.
Minuk Gerald Y +3 more
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Role of cytoglobin, a novel radical scavenger, in stellate cell activation and hepatic fibrosis [PDF]
Clinical and Molecular Hepatology, 2020 Cytoglobin (Cygb), a stellate cell-specific globin, has recently drawn attention due to its association with liver fibrosis. In the livers of both humans and rodents, Cygb is expressed only in stellate cells and can be utilized as a marker to distinguish
Le Thi Thanh Thuy +2 more
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Nitric oxide signals are interlinked with calcium signals in normal pancreatic stellate cells upon oxidative stress and inflammation [PDF]
Open Biology, 2016 The mammalian diffuse stellate cell system comprises retinoid-storing cells capable of remarkable transformations from a quiescent to an activated myofibroblast-like phenotype.
Monika A. Jakubowska +4 more
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Diagnostic Pathology, 2007 Folliculo-stellate cells are a nonendocrine, sustentacular-like complementary population of the anterior pituitary. They currently are considered as functionally and phenotypically heterogeneous, with one subpopulation of folliculo-stellate cells ...
Kappeler Andreas +2 more
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Cardiovascular Disease and its Association with Histological Changes of the Left stellate Ganglion
Clinical Medicine Insights: Pathology, 2010 Mounting evidence has demonstrated that the autonomic system plays a role in the morbidity and mortality of certain cardiovascular disease states. Ventricular arrhythmias have been associated with the level of sympathetic activation.
Adam Wood +2 more
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The Wilms' tumor suppressor gene regulates pancreas homeostasis and repair. [PDF]
PLoS Genetics, 2019 The Wilms' tumor suppressor gene (Wt1) encodes a zinc finger transcription factor that plays an essential role in the development of kidneys, gonads, spleen, adrenals and heart.
Laura Ariza +3 more
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Cell Death and Disease, 2023 Hepatic stellate cell is one of the major nonparenchymal cell types in liver. It has been proved the hepatic stellate cells are activated upon liver injury and produce excessive extracellular matrix to induce liver fibrosis.
Mengfan Zhang +9 more
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Frontiers in Physiology, 2019 Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest epithelial malignancies and remains difficult to treat. Pancreatic intraepithelial neoplasias (PanINs) represent the majority of the pre-cancer lesions in the pancreas.
Ce Li +11 more
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