Results 11 to 20 of about 71,053 (265)
Hepatic Stellate Cells and Hepatocarcinogenesis [PDF]
Frontiers in Cell and Developmental Biology, 2020 Hepatic stellate cells (HSCs) are a significant component of the hepatocellular carcinoma (HCC) tumor microenvironment (TME). Activated HSCs transform into myofibroblast-like cells to promote fibrosis in response to liver injury or chronic inflammation, leading to cirrhosis and HCC.
Anna E. Barry +12 more
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A Transcriptional Sequencing Analysis of Islet Stellate Cell and Pancreatic Stellate Cell [PDF]
Journal of Diabetes Research, 2018 Background. Our previous studies have shown that islet stellate cell (ISC), similar to pancreatic stellate cell (PSC) in phenotype and biological characters, may be responsible for the islet fibrosis in type 2 diabetes. To further identify the differences between PSC and ISC and for better understanding of the physiological function of ISC, we employed
Xiaohang Wang +12 more
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Shedding light on stellate cells [PDF]
eLife, 2018 The relationship between grid cells and two types of neurons found in the medial entorhinal cortex has been clarified.
Andrew S Alexander, Michael E Hasselmo
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iScience, 2023 Summary: Pancreatic stellate cells (PSCs) are suggested to play an important role in the development of pancreas and islet fibrosis. However, the precise contributions and solid in vivo evidence of PSCs to the fibrogenesis remain to be elucidated.
Jinbang Wang +11 more
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Hepatic Stellate Cells Support Hematopoiesis and are Liver-Resident Mesenchymal Stem Cells
Cellular Physiology and Biochemistry, 2013 Background/Aims: Hematopoiesis can occur in the liver, when the bone marrow fails to provide an adequate environment for hematopoietic stem cells.
Claus Kordes +3 more
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Cells, 2019 Although methionine sulfoxide reductase (Msr) is known to modulate the activity of multiple functional proteins, the roles of Msr in pancreatic stellate cell physiology have not been reported.
Jin Shuai Liu, Zong Jie Cui
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The effect of conditioned media on the cellular proliferation of pancreatic cancer cells, pancreatic stellate cells, and myeloid-derived suppressor cells [PDF]
World Cancer Research JournalObjective: Pancreatic cancer has remained one of the most devastating diseases over the past two decades, with minimal improvements in survival rates. Its highly immunosuppressive tumour microenvironment is driven by secreted proteins, such as cytokines ...
Y. Chong +7 more
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Biomolecules, 2022 Hepatic steatosis and chronic hepatocyte damage ultimately lead to liver fibrosis. Key pathophysiological steps are the activation and transdifferentiation of hepatic stellate cells.
Maria Teresa Koenen +10 more
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Seven Steps to Stellate Cells [PDF]
Journal of Visualized Experiments, 2011 Hepatic stellate cells are liver-resident cells of star-like morphology and are located in the space of Disse between liver sinusoidal endothelial cells and hepatocytes(1,2). Stellate cells are derived from bone marrow precursors and store up to 80% of the total body vitamin A(1, 2).
Patrick, Maschmeyer +2 more
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Functional properties of stellate cells in medial entorhinal cortex layer II
eLife, 2018 Layer II of the medial entorhinal cortex (MEC) contains two principal cell types: pyramidal cells and stellate cells. Accumulating evidence suggests that these two cell types have distinct molecular profiles, physiological properties, and connectivity ...
David C Rowland +6 more
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