Results 21 to 30 of about 71,053 (265)

Identification of an inhibitory neuron subtype, the L-stellate cell of the cochlear nucleus

eLife, 2020
Auditory processing depends upon inhibitory signaling by interneurons, even at its earliest stages in the ventral cochlear nucleus (VCN). Remarkably, to date only a single subtype of inhibitory neuron has been documented in the VCN, a projection neuron ...
Tenzin Ngodup, Gabriel E Romero, Laurence O Trussell   +2 more
doaj   +1 more source

Differential Lipotoxic Effects of Palmitate and Oleate in Activated Human Hepatic Stellate Cells and Epithelial Hepatoma Cells

Cellular Physiology and Biochemistry, 2016
Background/Aims: Nonalcoholic fatty liver disease (NAFLD) progression to fibrosis, cirrhosis and hepatocellular carcinoma, alters the cellular composition of this organ.
Alexandra M. Hetherington, Cynthia G. Sawyez, Emma Zilberman, Alexandra M. Stoianov, Debra L. Robson, Nica M. Borradaile   +5 more
doaj   +1 more source

Hepatic stellate cell progenitor cells [PDF]

Journal of Gastroenterology and Hepatology, 2012
AbstractHepatic stellate cells (HSCs) are recognized as a major player in liver fibrogenesis. Upon liver injury, HSCs differentiate into myofibroblasts and participate in progression of fibrosis and cirrhosis. Additional cell types such as resident liver fibroblasts/myofibroblasts or bone marrow cells are also known to generate myofibroblasts.
openaire   +2 more sources

Effects of dietary retinoid and triglyceride on the lipid composition of rat liver stellate cells and stellate cell lipid droplets

Journal of Lipid Research, 1988
Hepatic stellate cells store the majority of the liver's retinoid (vitamin A) reserves as retinyl esters in stellate cell lipid droplets. A study was conducted to explore the effects of differences in dietary retinoid and triglyceride intake on the ...
H Moriwaki, W S Blaner, R Piantedosi, D S Goodman   +3 more
doaj   +1 more source

Folliculo-stellate cells of "true dendritic" type are involved in the inflammatory microenvironment of tumor immunosurveillance of pituitary adenomas

Diagnostic Pathology, 2007
Folliculo-stellate cells are a nonendocrine, sustentacular-like complementary population of the anterior pituitary. They currently are considered as functionally and phenotypically heterogeneous, with one subpopulation of folliculo-stellate cells ...
Kappeler Andreas, Vajtai Istvan, Sahli Rahel   +2 more
doaj   +1 more source

Extracellular Vesicles from Ocular Melanoma Have Pro-Fibrotic and Pro-Angiogenic Properties on the Tumor Microenvironment

Cells, 2022
Uveal melanoma (UM) is the most common primary intraocular tumor and often spreads to the liver. Intercellular communication though extracellular vesicles (EVs) plays an important role in several oncogenic processes, including metastasis, therapeutic ...
Léo Piquet, Kelly Coutant, Andrew Mitchell, Amel Ben Anes, Enola Bollmann, Nathan Schoonjans, Julie Bérubé, François Bordeleau, Alain Brisson, Solange Landreville   +9 more
doaj   +1 more source

Hydrostatic pressure induces profibrotic properties in hepatic stellate cells via the RhoA/ROCK signaling pathway

FEBS Open Bio, 2022
Elevated interstitial fluid hydrostatic pressure is commonly observed in diseased livers. We herein examined the hypothesis that hydrostatic pressure induces hepatic stellate cells to acquire profibrotic properties under pathological conditions.
Zisheng Huang, Mahmoud Osman Khalifa, Weili Gu, Tao‐Sheng Li   +3 more
doaj   +1 more source

Toll-Like Receptor Signaling and Liver Fibrosis

Gastroenterology Research and Practice, 2010
Liver fibrosis occurs as a wound-healing scar response following acute and chronic liver inflammation including alcoholic liver disease, non-alcoholic steatohepatitis, hepatitis B and C, and autoimmune hepatitis.
Tomonori Aoyama, Yong-Han Paik, Ekihiro Seki   +2 more
doaj   +1 more source

Fusion Protein of RBP and Albumin Domain III Reduces Lung Fibrosis by Inactivating Lung Stellate Cells

Biomedicines, 2023
Activated stellate cells play a role in fibrosis development in the liver, pancreas, and kidneys. The fusion protein R-III, which consists of retinol-binding protein and albumin domain III, has been demonstrated to attenuate liver and renal fibrosis by ...
Jaeho Choi, Yuna Son, Ji Wook Moon, Dae Won Park, Young-Sik Kim, Junseo Oh   +5 more
doaj   +1 more source

Effect of Caloric Restriction on Hepatic Sinusoidal System and Stellate Cells in Mice

Journal of Aging Research, 2014
Aging associated changes in liver include reduced hepatic blood flow, increased number of stellate cells, and collagen deposits in perisinusoidal space. We tested the possibility of mitigating these changes with caloric restriction.
Jian Chen, Kara King, Jian X. Zhang
doaj   +1 more source