Results 91 to 100 of about 4,104 (181)

κ-Carrageenan-Based Hydrogels Support Viability and Odontogenic Differentiation of Stem Cells From the Apical Papilla

International Dental Journal
Introduction and Aims: Immature teeth with pulp necrosis remain challenging because conventional root canal treatment does not restore pulp-dentin vitality.
Muneera A. Alajlan, Rhodanne Nicole A. Lambarte, Terrence S. Sumague, Abdurahman A. Niazy   +3 more
doaj   +1 more source

SFRP2 enhances the osteogenic differentiation of apical papilla stem cells by antagonizing the canonical WNT pathway

Cellular & Molecular Biology Letters, 2017
Background Exploring the molecular mechanisms underlying directed differentiation is helpful in the development of clinical applications of mesenchymal stem cells (MSCs).
Luyuan Jin, Yu Cao, Guoxia Yu, Jinsong Wang, Xiao Lin, Lihua Ge, Juan Du, Liping Wang, Shu Diao, Xiaomeng Lian, Songlin Wang, Rui Dong, Zhaochen Shan   +12 more
doaj   +1 more source

Development of a Nano‐Hybrid Composite Using Bovine Hydroxyapatite and Montmorillonite for Endodontic Applications—An In Vitro Study

International Endodontic Journal, Volume 59, Issue 9, Page 1936-1953, September 2026.
ABSTRACT Aim Hydraulic calcium silicate cements are widely employed in endodontics due to their excellent biocompatibility, bioactivity, sealing ability, and remineralisation potential. However, currently used products such as mineral trioxide aggregate (MTA) exhibit several limitations, including discolouration, cost, and poor handling properties ...
P. A. A. S. Prasad Kumara, Paul R. Cooper, Peter Cathro, Henry F. Duncan, Maree Gould, George Dias, Jithendra Ratnayake   +6 more
wiley   +1 more source

Exploring the impact of oral bacteria remnants on stem cells from the Apical papilla: mineralization potential and inflammatory response. [PDF]

Front Cell Infect Microbiol, 2023
Zymovets V, Rakhimova O, Wadelius P, Schmidt A, Brundin M, Kelk P, Landström M, Vestman NR.   +7 more
europepmc   +1 more source

Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk

International Endodontic Journal, Volume 59, Issue 9, Page 1743-1759, September 2026.
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar, M. Huang, M. M. Abdalla, P. Neelakantan, C. K. Y. Yiu   +4 more
wiley   +1 more source

Regenerative Endodontics in Teeth With Irreversible Pulpitis: A Scoping Review

International Endodontic Journal, Volume 59, Issue 9, Page 1792-1803, September 2026.
ABSTRACT Introduction Regenerative endodontic procedures (REPs) have been widely used to manage a range of pulpal pathologies, particularly in immature permanent teeth. The development of bioactive calcium silicate–based materials has led to a paradigm shift in vital pulp therapy (VPT) and REPs.
Mahmoud Torabinejad, Neda Najafimakhsoos, George Bogen   +2 more
wiley   +1 more source

The evolutionary origins of streptophyte multicellularity

New Phytologist, Volume 251, Issue 5, Page 2365-2383, September 2026.
The phylogeny of streptophytes and the deep origin of branching filamentous growth. Summary Over their more than 1 billion years of evolutionary history, streptophytes have repeatedly transitioned between unicellular, simple multicellular and complex multicellular forms.
Tatyana Darienko, Cäcilia F. Kunz, Elisa S. Goldbecker, Erika Endriulaitytė, Maaike J. Bierenbroodspot, Maike Lorenz, Iker Irisarri, Thomas Pröschold, Katharina Bürstenbinder, Henrik Buschmann, Jan de Vries   +10 more
wiley   +1 more source

Interkingdom Endodontic Biofilm Supernatant Induces a Biphasic Inflammatory and Metabolic Transcriptional Response in Dental Pulp Stem Cells In Vitro

Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Objectives To investigate how soluble byproducts derived from a four‐species endodontic biofilm model impact the viability, transcriptomic profile, and inflammatory response of human dental pulp stem cells (DPSCs). Methods A sterile‐filtered supernatant was extracted from an established interkingdom endodontic biofilm model comprising ...
Saeed S. Alqahtani, Sumaya Abusrewil, Othman Baradwan, Om Alkhir Alshanta, Ryan Kean, William McLean, Jason L. Brown, Christopher J. Nile   +7 more
wiley   +1 more source

Effect of copper oxide nanoparticles and light-emitting diode irradiation on the cell viability and osteogenic/odontogenic differentiation of human stem cells from the apical papilla. [PDF]

BMC Oral Health, 2023
Karkehabadi H, Rahmati A, Abbasi R, Farmany A, Najafi R, Behroozi R, Rezaei-Soufi L, Abbaspourrokni H.   +7 more
europepmc   +1 more source

Effects of Stromal Cell‐Derived Factor 1 on Osteoblast Activity During Orthodontic Tooth Movement

Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Objective This study aimed to clarify the relationship between stromal cell‑derived factor 1 (SDF‑1) and osteoblast‐related responses in periodontal ligament (PDL) during orthodontic tooth movement (OTM) after tooth extraction, based on the hypothesis that local inhibition of SDF‑1/C‑X‑C chemokine receptor type 4 (CXCR4) signaling with the ...
Yoshiyuki Hamada, Yuji Ishida, Albert Chun‐Shuo Huang, Kenta Hamahara, Duangtawan Rintanalert, Kai Li, Kasumi Hatano‐Sato, Jun Hosomichi, Risa Usumi‐Fujita, Takashi Ono   +9 more
wiley   +1 more source