Results 1 to 10 of about 174,861 (241)
Stereocontrolled synthesis and nuclear magnetic resonance analysis of boranophosphate/phosphate chimeric oligonucleotides [PDF]
Royal Society Open ScienceThis report describes the stereoselective synthesis of boranophosphate/phosphate (PB/PO) chimeric oligodeoxynucleotides (ODNs) and the nuclear magnetic resonance (NMR) analysis of oligomers containing PB linkages.
Kiyoshi Kakuta +4 more
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Unexpected Methyllanthionine Stereochemistry in the Morphogenetic Lanthipeptide SapT
Journal of the American Chemical Society, 2022 Lanthipeptides are polycyclic peptides characterized by the presence of lanthionine (Lan) and/or methyllanthionine (MeLan). They are members of the ribosomally synthesized and post-translationally modified peptides (RiPPs).
Raymond Sarksian +4 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 The resolution of the acute inflammatory response is governed by phagocytes actively clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving mediators (SPMs) is pivotal in the resolution of inflammation via their roles in ...
Stephania Libreros +6 more
semanticscholar +1 more source
Stereochemistry-Controlled Mechanical Properties and Degradation in 3D-Printable Photosets.
Journal of the American Chemical Society, 2021 Stereochemistry provides an appealing handle by which to control the properties of small molecules and polymers. While it is established that stereochemistry in linear polymers affects their bulk mechanical properties, the application of this concept to ...
Anissa L Khalfa, M. Becker, A. P. Dove
semanticscholar +1 more source
Stereochemistry of N-Acyl-5H-dibenzo[b,d]azepin-7(6H)-ones
Molecules, 2023 The stereochemical properties of N-acyl-5H-dibenzo[b,d]azepin-7(6H)-ones (2a–c), which inhibit potassium channels in T cells, were examined by freezing their conformational change due to 4-methyl substitution.
Arisa Chiba +8 more
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Synthesis of New C-3 Substituted Kynurenic Acid Derivatives
Molecules, 2020 The application of kynurenic acid (KYNA) as an electron-rich aromatic system in the modified Mannich reaction has been examined. The extension possibility of the reaction was tested by using amines occurring in a number of bioactive products, such as ...
Bálint Lőrinczi +3 more
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Fast and Accurate Prediction of Refractive Index of Organic Liquids with Graph Machines
Molecules, 2023 The refractive index (RI) of liquids is a key physical property of molecular compounds and materials. In addition to its ubiquitous role in physics, it is also exploited to impart specific optical properties (transparency, opacity, and gloss) to ...
François Duprat +3 more
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A global Ramachandran score identifies protein structures with unlikely stereochemistry
bioRxiv, 2020 Ramachandran plots report the distribution of the (φ, Ψ) torsion angles of the protein backbone and are one of the best quality metrics of experimental structure models. Typically, validation software reports the number of residues belonging to “outlier”,
O. Sobolev +6 more
semanticscholar +1 more source
Synthesis and Conformational Analysis of Naphthoxazine-Fused Phenanthrene Derivatives
Molecules, 2020 The synthesis of new phenanthr[9,10-e][1,3]oxazines was achieved by the direct coupling of 9-phenanthrol with cyclic imines in the modified aza-Friedel–Crafts reaction followed by the ring closure of the resulting bifunctional aminophenanthrols with ...
Khadija Belasri +6 more
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Chemistry, Cyclophosphamide, Cancer Chemotherapy, and Serendipity: Sixty Years On
Substantia, 2021 Cambridge Dictionary: serendipity | noun | the phenomenon of finding interesting or valuable things by chance. The year 2019 marked the 60th anniversary of the approval of cyclophosphamide (CP) as an anticancer by the U.S.
Gerald Zon
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