Results 151 to 160 of about 58,537 (265)

Stereochemistry of the Electrochemical Hydrodimerization Reaction of Benzylidenemalononitrile. Dependence on Different Parameters. [PDF]

open access: bronze, 1987
Steen Uttrup Pedersen   +4 more
openalex   +1 more source

Investigating the molecular mechanisms underlying the anti‐CRISPR function of AcrIIA13b protein

open access: yesThe FEBS Journal, EarlyView.
Anti‐CRISPR protein AcrIIA13b inhibits CRISPR–Cas9 function by preventing target DNA engagement. The Cas9–sgRNA ribonucleoprotein (RNP) normally recognizes the protospacer adjacent motif (PAM) duplex to initiate DNA cleavage. AcrIIA13b binding to the PAM‐interacting WED–PI domain blocks this recognition, leaving the target DNA intact.
So Yeon Lee, Hyun Ho Park
wiley   +1 more source

Regio- and Stereoselective Halogenation by an Iron(II)- and 2-Oxoglutarate-Dependent Halogenase in the Biosynthesis of Halogenated Nucleosides. [PDF]

open access: yesJ Am Chem Soc
Palacios PM   +7 more
europepmc   +1 more source

Expanding the substrate scope of a bacterial monoterpene synthase for the production of sesquiterpenoid and diterpenoid products

open access: yesThe FEBS Journal, EarlyView.
We have converted the only known true bacterial monoterpene synthase, cineole synthase from Streptomyces clavuligerus (bCinS, C10 substrate), to a highly competent sesquiterpene synthase (C15) with a minimum number of rational mutations. By comparison with diterpene synthases (C20), we were then able to bestow diterpene synthase activity on bCinS. This
Nicole G. H. Leferink   +3 more
wiley   +1 more source

De Novo Design and Asymmetric Synthesis of a <i>C</i>-1/2 Benzodioxin Fused Glycoside Analogue of Lincomycin. [PDF]

open access: yesOrg Lett
Hicks I   +6 more
europepmc   +1 more source

Drivers of strigolactone diversity: P450s in strigolactone biosynthesis

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review summarizes the discovery and functional identification of cytochrome P450 in strigolactone biosynthesis, classifies and summarizes the members discovered so far, clarifies their biological significance, discusses the technology of strigolactone synthesis research, and finally describes some problems in strigolactone research and potential ...
Changbin Niu   +2 more
wiley   +1 more source

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