Results 161 to 170 of about 58,537 (265)

Isolation, structure revision and stereochemistry of trichomycins A and B, aromatic analogues of amphotericin B [PDF]

open access: gold
Tomasz Laskowski   +8 more
openalex   +1 more source

Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context

open access: yesJournal of Integrative Plant Biology, EarlyView.
Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac   +15 more
wiley   +1 more source

CANDID-CNS: AI Unlocks Stereochemistry and Beyond Rule of 5 to Predict CNS Penetration of Small Molecules. [PDF]

open access: yesJ Chem Inf Model
Collins JW   +5 more
europepmc   +1 more source

A Plant‐Based Platform for the Production of Bark Beetle Pheromones

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Bark beetle species of the genera Ips and Dendroctonus represent a threat to forests in both North America and Europe. Under normal circumstances, these beetles recycle dying trees into nutrients, but under certain conditions, growing populations can overcome healthy tree defenses and cause severe economic loss in forestry.
Abraham Ontiveros‐Cisneros   +7 more
wiley   +1 more source

Terpenes as Naturally Occurring Stereochemical Templates: Conformationally Driven Discovery of Reactivity. [PDF]

open access: yesOrg Lett
Arto O   +6 more
europepmc   +1 more source

Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Jongbu Lim   +16 more
wiley   +1 more source

Asymmetric Hydride Shift Reactions Catalyzed by Chiral Aluminium Complexes

open access: yesAngewandte Chemie, Volume 138, Issue 5, 28 January 2026.
An asymmetric intramolecular hydride shift reaction has been developed that is catalyzed by Al Lewis acids in conjunction with a chiral BINOL‐derived ligand. Racemic THP substrates are transformed into cyclohexene products via an intermediate prochiral enone; which undergoes a key 1,5‐hydride shift reaction.
Mostafa M. Amer   +4 more
wiley   +2 more sources

Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion. [PDF]

open access: yesNat Commun
Hwang J   +21 more
europepmc   +1 more source

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