Results 181 to 190 of about 177,307 (324)

Cyclic Tetraindoles With a Cyclooctatetraene Core: Controlling Planarity and Antiaromatic Character via N‐Alkylation

Chemistry – A European Journal, EarlyView.
We report cyclic tetraindole derivatives incorporating a central cyclooctatetraene (COT) ring, where molecular distortion is tuned by N‐alkylation. Increasing planarity through ethylene linkers enhances π‐conjugation and antiaromaticity, accompanied by red‐shifted absorption, lower oxidation potentials, and a reduced HOMO–LUMO gap, providing insights ...
Keisuke Fujimoto, Ryo Hirose, Hyuma Masu, Masaki Takahashi   +3 more
wiley   +1 more source

Terpenes as Naturally Occurring Stereochemical Templates: Conformationally Driven Discovery of Reactivity. [PDF]

Org Lett
Arto O, Miguélez R, Siera H, Schulte J, Merino I, Haberhauer G, Barrio P.   +6 more
europepmc   +1 more source

Bookreview, Basic Organic Stereochemistry [PDF]

, 2001
Ian J. S. Fairlamb
openalex   +1 more source

Stereochemistry of the Brivaracetam Diastereoisomers.

Chirality, 2016
Shi Qiu, K. Tehrani, S. Sergeyev, P. Bultinck, W. Herrebout, B. Mathieu   +5 more
semanticscholar   +1 more source

Synthesis and Evaluation of Fluorinated Peptidomimetics Enabling the Development of 18F‐Labeled Radioligands Targeting Muscarinic Acetylcholine Receptor Subtype M3

ChemMedChem, EarlyView.
Fluorinated peptidomimetics targeting muscarinic acetylcholine receptor subtype M3: Fluorinated peptidomimetic compounds based on a β‐alanine‐glycine scaffold, with lead compound 24 demonstrating high M3 selectivity and submicromolar potency. The first M3‐selective positron emission tomography radioligand, [18F]24, is synthesized and will be evaluated ...
Miguel A. Herrera‐Rueda, Maxwell A. Boateng, Melinda Wuest, Frederick G. West, Frank Wuest   +4 more
wiley   +1 more source

Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion. [PDF]

Nat Commun
Hwang J, Kirshner J, Deschênes DAR, Richardson MB, Fleck SJ, Mann SGA, Guo J, Perley JO, Shahsavarani M, Garza-Garcia JJO, Seveck AD, Doiron SS, Mai Z, Silliphant SN, Englehart SA, Blight BA, Calhoun L, Gao D, Lian J, Deslongchamps G, Albert VA, Qu Y.   +21 more
europepmc   +1 more source

Intramolecular Pd-Catalyzed Carboetherification and Carboamination. Influence of Catalyst Structure on Reaction Mechanism and Product Stereochemistry

, 2006
Josephine S. Nakhla, Jeff W. Kampf, John P. Wolfe   +2 more
openalex   +1 more source

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

ChemPlusChem, EarlyView.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

Development of a Stereoselective Synthesis of Isomers of (+)-Disorazole Z1's Lateral Chain. [PDF]

J Org Chem
Bauer TJ, Köhler P, Spieß O, Schinzer D.   +3 more
europepmc   +1 more source

Absolute stereochemistry of fungal metabolites: icterinoidins A1 and B1, and atrovirins B1 and B2

, 2004
Melvyn Gill, Peter M. Morgan
openalex   +2 more sources