Results 11 to 20 of about 176,257 (369)
Stereochemistry-Controlled Mechanical Properties and Degradation in 3D-Printable Photosets.
Journal of the American Chemical Society, 2021 Stereochemistry provides an appealing handle by which to control the properties of small molecules and polymers. While it is established that stereochemistry in linear polymers affects their bulk mechanical properties, the application of this concept to ...
Anissa L Khalfa, M. Becker, A. P. Dove
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Synthesis of New C-3 Substituted Kynurenic Acid Derivatives
Molecules, 2020 The application of kynurenic acid (KYNA) as an electron-rich aromatic system in the modified Mannich reaction has been examined. The extension possibility of the reaction was tested by using amines occurring in a number of bioactive products, such as ...
Bálint Lőrinczi +3 more
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Fast and Accurate Prediction of Refractive Index of Organic Liquids with Graph Machines
Molecules, 2023 The refractive index (RI) of liquids is a key physical property of molecular compounds and materials. In addition to its ubiquitous role in physics, it is also exploited to impart specific optical properties (transparency, opacity, and gloss) to ...
François Duprat +3 more
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A global Ramachandran score identifies protein structures with unlikely stereochemistry
bioRxiv, 2020 Ramachandran plots report the distribution of the (φ, Ψ) torsion angles of the protein backbone and are one of the best quality metrics of experimental structure models. Typically, validation software reports the number of residues belonging to “outlier”,
O. Sobolev +6 more
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Synthesis and Conformational Analysis of Naphthoxazine-Fused Phenanthrene Derivatives
Molecules, 2020 The synthesis of new phenanthr[9,10-e][1,3]oxazines was achieved by the direct coupling of 9-phenanthrol with cyclic imines in the modified aza-Friedel–Crafts reaction followed by the ring closure of the resulting bifunctional aminophenanthrols with ...
Khadija Belasri +6 more
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Chemistry, Cyclophosphamide, Cancer Chemotherapy, and Serendipity: Sixty Years On
Substantia, 2021 Cambridge Dictionary: serendipity | noun | the phenomenon of finding interesting or valuable things by chance. The year 2019 marked the 60th anniversary of the approval of cyclophosphamide (CP) as an anticancer by the U.S.
Gerald Zon
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Molecular Therapy: Nucleic Acids, 2021 The 599 peptide has been previously shown to effectively deliver small interfering RNAs (siRNAs) to cancer cells, inducing targeted-oncogene silencing, with a consequent inhibition of tumor growth. Although effective, this study was undertaken to advance
Charles E. Holjencin +10 more
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Solvent-Free C-3 Coupling of Azaindoles with Cyclic Imines
Molecules, 2019 By direct coupling 7-azaindole and cyclic imines, such as 3,4-dihydroisoquinoline, 6,7-dihydrothieno[3,2-c]pyridine, 3,4-dihydro-β-carboline, and 4,5-dihydro-3H-benz[c]azepine, new 3-substituted 7-azaindole derivatives have been synthesized.
Khadija Belasri +2 more
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Femtosecond dynamics of hydrogen elimination: benzene formation from cyclohexadiene [PDF]
, 2000 Using femtosecond-resolved mass spectrometry in a molecular beam, we report real-time study of the hydrogen elimination reaction of 1,4-cyclohexadiene. The experimental observation of the ultrafast stepwise H-elimination elucidates the reaction dynamics ...
De Feyter, Steven +2 more
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Stereo-Aware Extension of HOSE Codes [PDF]
, 2019 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Descriptions of molecular environments have many applications in chemoinformatics, including chemical shift
Johnson, Sean R., Kuhn, Stefan
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