Results 21 to 30 of about 138,145 (310)

Addition of Di(trimethylsilyl) Phosphite to Schiff Bases of 2,5-Diformylfuran [PDF]

open access: yes, 2011
A series of 2,5-Furanyl-bis-(aminomethylphosphonic Acids) has been synthesized by the addition of di(trimethylsilyl) phosphite to azomethine bond of achiral Schiff bases derved from 2,5-diformylfuran.
Ciechańska, Magdalena   +3 more
core   +1 more source

Focus on chirality of HIV-​1 non-​nucleoside reverse transcriptase inhibitors [PDF]

open access: yes, 2016
Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
core   +5 more sources

Femtosecond dynamics of hydrogen elimination: benzene formation from cyclohexadiene [PDF]

open access: yes, 2000
Using femtosecond-resolved mass spectrometry in a molecular beam, we report real-time study of the hydrogen elimination reaction of 1,4-cyclohexadiene. The experimental observation of the ultrafast stepwise H-elimination elucidates the reaction dynamics ...
De Feyter, Steven   +2 more
core   +1 more source

Ortho‐Quinone Methide Driven Synthesis of New O,N‐ or N,N‐Heterocycles

open access: yesChemistryOpen, 2019
To synthesize functionalized Mannich bases that can serve two different types of ortho‐quinone methide (o‐QM) intermediates, 2‐naphthol and 6‐hydroxyquinoline were reacted with salicylic aldehyde in the presence of morpholine.
Dr. István Szatmári   +5 more
doaj   +1 more source

Chiral Aspects of Local Anesthetics

open access: yesMolecules, 2020
Thanks to the progress made in chemical technology (particularly in the methodologies of stereoselective syntheses and analyses) along with regulatory measures, the number of new chiral drugs registered in the form of pure enantiomers has increased over ...
Ružena Čižmáriková   +4 more
doaj   +1 more source

Organic chemistry lecture course and exercises based on true scale models

open access: yesChemistry Teacher International, 2020
3D models of chemical structures are an important tool for chemistry lectures and exercises. Usually, simplified models based on standard bond length and angles are used.
Lederle Felix, Hübner Eike G.
doaj   +1 more source

Fast and Accurate Prediction of Refractive Index of Organic Liquids with Graph Machines

open access: yesMolecules, 2023
The refractive index (RI) of liquids is a key physical property of molecular compounds and materials. In addition to its ubiquitous role in physics, it is also exploited to impart specific optical properties (transparency, opacity, and gloss) to ...
François Duprat   +3 more
doaj   +1 more source

Plasma analysis of di- and trihydroxycholestanoic acid diastereoisomers in peroxisomal α-methylacyl-CoA racemase deficiency

open access: yesJournal of Lipid Research, 2001
We identified a new peroxisomal disorder caused by a deficiency of the enzyme α-methylacyl-coenzyme A (CoA) racemase. Patients with this disorder show elevated plasma levels of pristanic acid and the bile acid intermediates di- and trihydroxycholestanoic
Sacha Ferdinandusse   +5 more
doaj   +1 more source

Diels–Alder reaction of β-fluoro-β-nitrostyrenes with cyclic dienes

open access: yesBeilstein Journal of Organic Chemistry, 2021
The Diels–Alder reaction of β-fluoro-β-nitrostyrenes with cyclic 1,3-dienes was investigated. A series of novel monofluorinated norbornenes was prepared in up to 97% yield.
Savva A. Ponomarev   +7 more
doaj   +1 more source

Teaching Stereochemistry with Multimedia and Hands-On Models: The Relationship between Students’ Scientific Reasoning Skills and The Effectiveness of Model Type

open access: yesCenter for Educational Policy Studies Journal
This paper presents an analysis of the use of multimedia and hands-on models on university students’ understanding of stereochemistry. The relationship between students’ scientific reasoning skills and their understanding of stereochemistry was also ...
Rooserina Kusumaningdyah   +5 more
doaj   +1 more source

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