Results 21 to 30 of about 174,911 (284)
Mannich base-connected syntheses mediated by ortho-quinone methides
This article provides an overview about specifically modified Mannich reactions where the process involves an ortho-quinone methide (o-QM) intermediate.
Petra Barta+2 more
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There is a renewed interest in computer-aided synthesis planning, where the vast majority of approaches require the application of retrosynthetic reaction templates.
Connor W. Coley, W. Green, K. Jensen
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X-ray Diffraction, Electronic Circular Dichroism, and Quantum Mechanics (TD-DFT) Investigations on 4 Dehydroxyaltersolanol A, a Secondary Metabolite from Endophytic Fungus Nigrospora oryzae [PDF]
Background and objectives: A tetrahydro anthraquinone derivative, 4-dehydroxyaltersolanol A, has been obtained from Nigrospora oryzae, which was isolated from Uncaria borneensis Havil as an endophytic fungus.
Fatimah Bebe Mohamed Hussain+8 more
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New Antibacterial Diterpenoids from the South China Sea Soft Coral Klyxum molle
Fifteen new diterpenoids, namely xishaklyanes A-O (1–15), along with three known related ones (16–18), were isolated from the soft coral Klyxum molle collected from Xisha Islands, South China Sea.
Jia-Dong Yu+5 more
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NMR data prediction is increasingly important in structure elucidation. The impact of force field selection was assessed, along with geometry and energy cutoffs.
Cristina Cuadrado+2 more
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Structure and stereochemistry of the base excision repair glycosylase MutY reveal a mechanism similar to retaining glycosidases. [PDF]
MutY adenine glycosylases prevent DNA mutations by excising adenine from promutagenic 8-oxo-7,8-dihydroguanine (OG):A mismatches. Here, we describe structural features of the MutY active site bound to an azaribose transition state analog which indicate a
Cao, Sheng+6 more
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The Stereochemistry of Ketoreduction [PDF]
In this issue of Chemistry & Biology, Leadlay and coworkers report overproduction of a number of ketoreductase domains from modular polyketide synthases. These discrete enzymes allow the stereochemistry of polyketide ketoreduction to be studied in isolation.
openaire +3 more sources
Contribution of the Chemistry Institutes to the Early Development of Stereochemistry
This article is a translation from German of a paper submitted by Kurt Hermann to the University of Zurich Prize committee in 1968, with additional editing by Jay Siegel.
Kurt Hermann
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Chiral 2-substituted chromanes are important substructures in organic synthesis and appear in numerous natural products. Herein, the correlation between specific optical rotations (SORs) and the stereochemistry at C2 of chiral 2-substituted chromanes was
Bei-Bei Yang+5 more
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