Results 51 to 60 of about 174,911 (284)

Botrylactone: new interest in an old moleculedreview of its absolute configuration and related compounds [PDF]

open access: yes, 2010
The absolute configuration of botrylactone, a unique compound with an interesting polyketide lactone skeleton with two oxirane bridges previously isolated from Botrytis cinerea and described as a powerful antibiotic, has been reviewed on the basis of ...
Durán Patrón, Rosa María   +4 more
core   +2 more sources

Prediction of Stereochemistry using Q2MM

open access: yesAccounts of Chemical Research, 2016
Conspectus The standard method of screening ligands for selectivity in asymmetric, transition metal-catalyzed reactions requires experimental testing of hundreds of ligands from ligand libraries.
E. Hansen   +4 more
semanticscholar   +1 more source

A Concise Total Synthesis of (--)-Maoecrystal Z [PDF]

open access: yes, 2011
The first total synthesis of (--)-maoecrystal Z is described. The key steps of the synthesis include a diastereoselective Ti^(III)-mediated reductive epoxide coupling reaction and a diastereoselective Sm^(II)-mediated reductive cascade cyclization ...
Cha, Jacob Y.   +2 more
core   +2 more sources

Insights into the Phytochemistry of the Cuban Endemic Medicinal Plant Phyllanthus orbicularis: Fideloside, a Novel Bioactive 8-C-glycosyl 2,3-Dihydroflavonol

open access: yesMolecules, 2019
Phyllanthus orbicularis (Phyllanthaceae) is an endemic evergreen tropical plant of Cuba that grows in the western part of the island and is used in traditional medicine as an infusion.
Antonio Francioso   +8 more
doaj   +1 more source

On biological homochirality [PDF]

open access: yes, 2009
Generalizing Landau's spontaneous symmetry breaking arguments using the standard groupoid approach to stereochemistry allows reconsideration of the origin of biological homochirality.
Rodrick Wallace
core   +1 more source

Focus on chirality of HIV-​1 non-​nucleoside reverse transcriptase inhibitors [PDF]

open access: yes, 2016
Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
core   +2 more sources

A unique bacteriohopanetetrol stereoisomer of marine anammox [PDF]

open access: yes, 2020
Anaerobic ammonium oxidation (anammox) is a major process of bioavailable nitrogen removal from marine systems. Previously, a bacteriohopanetetrol (BHT) isomer, with unknown stereochemistry, eluting later than BHT using high performance liquid ...
Alex Charlton, E.   +14 more
core   +4 more sources

Synthesis and Oxidative Transformations of New Chiral Pinane-Type γ-Ketothiols: Stereochemical Features of Reactions

open access: yesMolecules, 2021
Chiral γ-ketothiols, thioacetates, thiobenzoate, disulfides, sulfones, thiosulfonates, and sulfonic acids were obtained from β-pinene for the first time.
Olga M. Lezina   +4 more
doaj   +1 more source

Confirmation of the stereochemistry of spiroviolene

open access: yesBeilstein Journal of Organic Chemistry, 2023
We confirm the previously revised stereochemistry of spiroviolene by X-ray crystallographically characterizing a hydrazone derivative of 9-oxospiroviolane, which is synthesized by hydroboration/oxidation of spiroviolene followed by oxidation of the resultant hydroxy group.
Yao Kong   +9 more
openaire   +3 more sources

Ceramide structural features required to stimulate ABCA1-mediated cholesterol efflux to apolipoprotein A-I

open access: yesJournal of Lipid Research, 2006
Ceramide is a component of the sphingomyelin cycle and a well-established lipid signaling molecule. We recently reported that ceramide specifically increased ABCA1-mediated cholesterol efflux to apolipoprotein A-I (apoA-I), a critical process that leads ...
Amy B. Ghering, W. Sean Davidson
doaj   +1 more source

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