Results 1 to 10 of about 20,087 (300)

Insights into the stereoisomerism of dihydroquercetin: analytical and pharmacological aspects [PDF]

Frontiers in Chemistry
Dihydroquercetin (DHQ) is a representative of flavonoids that is available on the market as a food supplement and registered as an active pharmaceutical ingredient.
Roman P. Terekhov, Anastasiya D. Savina, Denis I. Pankov, Maria D. Korochkina, Amir Taldaev, Amir Taldaev, Liubov M. Yakubovich, Sergey P. Zavadskiy, Anastasiya K. Zhevlakova, Irina A. Selivanova   +9 more
doaj   +2 more sources

Stereochemically-aware bioactivity descriptors for uncharacterized chemical compounds [PDF]

Journal of Cheminformatics
Stereochemistry plays a fundamental role in pharmacology. Here, we systematically investigate the relationship between stereoisomerism and bioactivity on over 1 M compounds, finding that a very significant fraction (~ 40%) of spatial isomer pairs show ...
Arnau Comajuncosa-Creus, Aksel Lenes, Miguel Sánchez-Palomino, Dylan Dalton, Patrick Aloy   +4 more
doaj   +2 more sources

Stereoisomerism of multi-functional electrolyte additives for initially anodeless aqueous zinc metal batteries [PDF]

Nature Communications
Stereoisomerism, arising from the distinctive spatial arrangements of atoms despite identical molecular formulae, often displays different chemical reactivities.
Shengyang Huang, Hao Fu, Hyun Min Kwon, Min Sung Kim, Jun-Dong Zhang, Jun Lu, Jun Su Kim, Gun Jang, Dong Hyun Min, Won Il Kim, Guanyao Wang, Wenwu Li, Rui Zhang, Sae Byeok Jo, Xiang Chen, Qiang Zhang, Kang Xu, Michel Armand, Ho Seok Park   +18 more
doaj   +2 more sources

Scientific Opinion on Flavouring Group Evaluation 82, Revision 1 (FGE.82Rev1): Consideration of Epoxides evaluated by the JECFA (65th meeting) [PDF]

EFSA Journal, 2014
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +4 more sources

Scientific Opinion on Flavouring Group Evaluation 11, Revision 3 (FGE.11Rev3): Aliphatic dialcohols, diketones, and hydroxyketones from chemical groups 8 and 10 [PDF]

EFSA Journal, 2014
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate 11 flavouring substances in the Flavouring Group Evaluation 11, Revision 3, using the Procedure in Commission ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids
doaj   +2 more sources

Preclinical characterisation of gallium-68 labeled ferrichrome siderophore stereoisomers for PET imaging applications [PDF]

EJNMMI Radiopharmacy and Chemistry
Background Siderophores are small iron-binding molecules produced by microorganisms to facilitate iron acquisition from the environment. Radiolabelled siderophores offer a promising solution for infection imaging, as they can specifically target the ...
Kristyna Krasulova, Barbora Neuzilova, Katerina Dvorakova Bendova, Zbynek Novy, Miroslav Popper, Marian Hajduch, Milos Petrik   +6 more
doaj   +2 more sources

Scientific Opinion on Flavouring Group Evaluation 67, Revision 1 (FGE.67Rev.1): Consideration of 40 furan‐substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re‐evaluated at the 69th meeting (JECFA, 2009c) [PDF]

EFSA Journal, 2011
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +2 more sources

Clinical Pharmacokinetics of Fexofenadine: A Systematic Review [PDF]

Pharmaceutics
Background/Objectives: Fexofenadine hydrochloride is a widely prescribed drug for treating histamine-mediated allergic reactions. This review systematically collates existing research on the clinical pharmacokinetics (PK) of fexofenadine, with a copious ...
Maryam Batool, Ammara Zamir, Faleh Alqahtani, Tanveer Ahmad, Hamid Saeed, Muhammad Fawad Rasool   +5 more
doaj   +2 more sources

Efficacy of Different Doses of Cisatracurium for Intubation during Surgeries under General Anaesthesia- A Randomised Clinical Study [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Cisatracurium is a new non depolarising, Neuromuscular Blocking Drug (NMBD) with fast onset and short duration of action. It is a stereoisomer of atracurium with a potency of approximately three to four times greater than that of atracurium.
Sana Ahmed Shaikh, Arati Bhaskar Jadhav, Archita Rajaram Patil, Anupama Deepak Sahasrabudhe   +3 more
doaj   +1 more source

Phenothiazine Derivatives: The Importance of Stereoisomerism in the Tolerance and Efficacy of Antimicrobials. [PDF]

Indian J Microbiol
Ronco T, Juul M, Reynier Z, Christensen JB, Svenningsen S, Olsen RH.   +5 more
europepmc   +3 more sources