Results 121 to 130 of about 20,087 (300)
Environmental Toxicology and Chemistry, EarlyView.Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
Food Safety and Health, EarlyView.Multiple OCP isomers and/or metabolites along with their parent compounds were detected in commonly consumed fruits and vegetables of Bangladesh, possibly attributed to both recently and historically applied OCPs. However, all the detected values were below 0.01 mg/kg, indicating no potential human health risks through dietary intake. ABSTRACT Globally,
Kazi Sanjana Adnen +4 more
wiley +1 more source
HIGHLIGTHS IN 1,2,3-DITHIAZOLE CHEMISTRY [PDF]
, 2010 Among the five-membered heterocycles containing nitrogen and sulphur atoms, 1,2,3-dithiazoles are important compounds due to their unusual physical properties, biological activity and versatile chemistry.
Emmanuel Deau +6 more
core
Spirocyclic Diamine Scaffolds for Medicinal Chemistry
Helvetica Chimica Acta, EarlyView.Here we enumerated 391 spirocyclic diamine drug scaffolds with ring sizes four to eight and found that most of them are unknown. We prepared four novel such spirocycles and discovered a micromolar inhibitor of the M4 muscarinic receptor. ABSTRACT Medicinal chemistry requires the exploration of structurally diverse compound families to expand the ...
Aline Carrel +3 more
wiley +1 more source
Solvent Induced Circular Dichroism in Conformational Analysis: Bile Pigments [PDF]
, 1981 Krauss, Corinna +2 more
core +1 more source
Synthesis of Biphenanthrene Natural Products by Atroposelective Aromatic Ring‐Opening Metathesis
Helvetica Chimica Acta, EarlyView.Aromatic ring‐opening metathesis in natural product total synthesis allows for the streamlined stereoselective preparation of atropisomeric biphenanthrenes with an enantioselectivity of >99:1 e.r. ABSTRACT With the unique ability to cleave and form an extensive range of carbon–carbon double and triple bonds, alkene and alkyne metathesis advanced to a ...
Valeriia Hutskalova, Christof Sparr
wiley +1 more source
Front Cover: Reversible Stereoisomer‐Specific Cotton Effect of the Ligand Field Transitions at a Copper(II) Binding Site of the Prion Protein (Eur. J. Inorg. Chem. 2/2022) [PDF]
, 2021 Lina Rivillas‐Acevedo +4 more
openalex +1 more source
Glucose‐Responsive Modified Poly(Propylene Imine) Dendrimer for Self‐Regulated Insulin Delivery
Macromolecular Materials and Engineering, EarlyView.Poly(propylene imine) dendrimers functionalized with phenolboronic acid (PBA) are synthesized and modified to develop a glucose‐sensitive system with a pKa of ∼7.4. Also, the equilibrium binding constant (Keq‐tet) for PBA‐attached G4 dendrimer (HB‐CBA) was determined to be 79 m−1.
Amin Hosseini Sharifabad +2 more
wiley +1 more source