Results 21 to 30 of about 20,087 (300)
Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) [PDF]
Urokinase-type plasminogen activator (uPA) represents a central molecule in pericellular proteolysis and is implicated in a variety of physiological and pathophysiological processes such as tissue remodelling, wound healing, tumor invasion, and ...
Arroyo de Prada, Nuria +10 more
core +1 more source
Stereoisomerism and Conformational Directionality (Prelog Lecture)
The inaugural Prelog Lecture provides me with a unique opportunity to pay tribute to a great scientist, teacher, and friend. As I hope to show, the work of Vladimir Prelog is profoundly relevant to the work that I want to describe today.
Kurt Mislow
doaj +1 more source
Out-of-plane deformations of metalloporphyrin skeletons have been well documented as playing important roles in relevant biological processes. In contrast, out-of-plane binding to the N-core of large metal cations as period 6 post-transition elements has
Barakat, Wael +5 more
doaj +1 more source
Antibiotic resistance (ABR) is now recognised as a serious global health and economic threat that is most efficiently managed via a ‘one health’ approach incorporating environmental risk assessment.
Felicity C.T. Elder +4 more
doaj +1 more source
The complexity of chemical components of herbal medicines often causes great barriers to toxicity research. In our previous study, we have found the critical divergent hepatotoxic potential of a pair of stilbene isomers in a famous traditional Chinese ...
Juan Liu +12 more
doaj +1 more source
Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]
The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D. +2 more
core +2 more sources
Computational exploration of the chemical structure space of possible reverse tricarboxylic acid cycle constituents [PDF]
The reverse tricarboxylic acid (rTCA) cycle has been explored from various standpoints as an idealized primordial metabolic cycle. Its simplicity and apparent ubiquity in diverse organisms across the tree of life have been used to argue for its antiquity
Fabienne d'Arripe-Longueville +3 more
core +7 more sources
Analysis of cis-isomer-enriched dihydroquercetin sample by 1D and 2D NMR spectroscopy
Introduction. The structure of dihydroquercetin (DHQ) is characterized by two chiral centers at positions 2 and 3 of the benzopyran cycle, resulting in possible diastereomers: trans- and cis-isomers.
R. P. Terekhov +5 more
doaj +1 more source
Amino acids (AAs) and ammonia are metabolic markers essential for nitrogen metabolism and cell regulation in both plants and humans. NMR provides interesting opportunities to investigate these metabolic pathways, yet lacks sensitivity, especially in case
Ewoud Vaneeckhaute +4 more
doaj +1 more source
We develop new bifacial chiral non‐fullerene acceptors (NFAs) for organic solar cells (OSCs). Through comparative investigations of four NFAs including meso, racemic, and chiral entries, we demonstrate the superiority of homochiral NFAs for the first time.
Shuang Li +4 more
wiley +2 more sources

