Results 61 to 70 of about 17,928 (220)

Synthesis of α‐Pentafluorosulfanylated‐β2,3‐Amino Esters

ChemistryEurope, EarlyView.
De novo α‐SF5‐β2,3‐amino esters are now accessible through a straightforward aza‐Michael reaction using a series of newly developed (E)‐α‐SF5‐α,β‐unsaturated esters. Two new, highly functionalized, contiguous tertiary stereocenters are formed with diastereodivergence governed by the choice of solvent and/or base.
Thi Mo Nguyen, Guilhem Colomer, Oscar Maugue‐Sauze, Nicolas Blanchard, Vincent Bizet, Dominique Cahard   +5 more
wiley   +1 more source

Synthesis and Characterization of New V_1A Antagonist Compounds: The Separation of Four Atropisomeric Stereoisomers

, 2021
Zsolt Szeleczky, Zoltán Szakács, Éva Bozó, Ferenc Baska, Krisztina Vukics, Sándor Lévai, K. Temesvári, Elemér Vass, Zoltán Béni, Balázs Krámos, Ildikó Magdó, Csaba Szántay, János Kóti, Katalin Domány-Kovács, István Greiner, Imre Bata   +15 more
openalex   +1 more source

Synthesis, identification, chiral separation and crystal structure of (3R,4R,7S,8S)-3,4,7,8-tetrachlorodecane and its stereoisomers [PDF]

, 2023
Solveig Valderhaug, Natalie Paškanová, Jiří Tůma, Jana Herciková, Václav Eigner, Huiling Liu, Alexey Gorovoy, Jon Eigill Johansen, Odd R. Gautun   +8 more
openalex   +1 more source

Gold(I)‐Catalyzed Domino Cyclization for the Construction of Trispirocyclic Cyclohexanes

ChemistryEurope, EarlyView.
We describe herein a series of intricate trispirocyclic architectures that have been synthesized from readily available substrates through an operationally simple one‐pot transformation under mild conditions. An unprecedented gold(I)‐catalyzed domino cyclization involving 2‐ethynylbenzyl alcohol derivatives and heterocyclic α,β‐unsaturated imines ...
Manon Genet, Jérôme Marrot, Isabelle Chataigner, Xavier Moreau   +3 more
wiley   +1 more source

Marine algae and their bioactive compounds as novel modulators for mitochondrial quality control: from mechanism to therapeutic potential

Frontiers in Marine Science
Mitochondrial Quality Control (MQC) is the core mechanism for ensuring mitochondrial quality and maintaining cellular function. Marine algae and their bioactive compounds represent a huge treasure trove of natural medicines.
Chi Zhang, Ling Yuan, Jingjing Li, Doudou Lu, Yuhua Du, Yi Nan   +5 more
doaj   +1 more source

Enantioselective Synthesis of Sulfinamidines via Asymmetric Rhodium–Catalyzed Imidation of Sulfenamides

ChemistryEurope, EarlyView.
In this work, a catalytic enantioselective imidation approach is presented for the preparation of enantioenriched sulfinamidines from sulfenamides, employing a chiral dirhodium(II) tetracarboxylate catalyst. This method enables the imidation of N,N‐bisalkyl sulfenamides in yields of up to 98% and enantiomeric ratios up to 98:2, with a catalyst loading ...
Michael Andresini, Théo Bissonnier, Juline Courtois, Pascal Retailleau, Benjamin Darses, Jean‐François Poisson, Tanguy Saget, Philippe Dauban   +7 more
wiley   +1 more source

THE STRUCTURE AND CONFORMATION OF LIGNIN AS JUDGED BY X-RAY CRYSTALLOGRAPHIC INVESTIGATIONS OF LIGNIN MODEL COMPOUNDS: ARYLGLYCEROL -SYRINGYL ETHERS

BioResources, 2009
Structural elements of the arylglycerol -syringyl ether type are very frequent in hardwood lignins. A variety of crystalline dimeric lignin models representing different diastereomeric forms of structural elements in lignin of this type have been ...
Knut Lundquist, Vratislav Langer, Jim Parkås   +2 more
doaj  

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

Computational insights into the stereo-selectivity of catechins for the inhibition of the cancer therapeutic target EGFR kinase

Frontiers in Pharmacology
The epidermal growth factor receptor (EGFR) plays a crucial role in regulating cellular growth and survival, and its dysregulation is implicated in various cancers, making it a prime target for cancer therapy.
Mohd Rehan, Mohd Rehan, Firoz Ahmed, Firoz Ahmed, Mohammad Imran Khan, Hifzur Rahman Ansari, Shazi Shakil, Shazi Shakil, Shazi Shakil, Moustafa E. El-Araby, Salman Hosawi, Mohammad Saleem, Mohammad Saleem   +12 more
doaj   +1 more source

Dual‐Mode Thio‐MacMillan Organocatalysts: Stereoselective Diels–Alder Reactions or Sacrificial Self‐Cyclization to N‐Bridged Bicyclic Lactams

Chemistry – A European Journal, EarlyView.
The study of the Diels–Alder reaction of cinnamaldehyde and cyclopentadiene, catalyzed by chiral imidazolidine‐4‐thiones, led to the discovery of a highly regio‐ and stereoselective Michael‐addition and consecutive ring closure. Here, the imidazolidine‐4‐thione not only catalytically activates cinnamaldehyde but also participates as the nucleophile to ...
Marian S. R. Ebeling, Luca V. Parziale, Marc Sachsenhauser, Christoph J. B. Seifert, Nathalie J. Kurrle, Oliver Trapp   +5 more
wiley   +1 more source