Results 11 to 20 of about 166,370 (359)

Aromatic C–H bond functionalization through organocatalyzed asymmetric intermolecular aza-Friedel–Crafts reaction: a recent update

Beilstein Journal of Organic Chemistry, 2023
The aza-Friedel–Crafts reaction allows an efficient coupling of electron-rich aromatic systems with imines for the facile incorporation of aminoalkyl groups into the aromatic ring. This reaction has a great scope of forming aza-stereocenters which can be
Anup Biswas
doaj   +1 more source

Stereoselective Toxicokinetic and Distribution Study on the Hexaconazole Enantiomers in Mice

Toxics, 2023
Hexaconazole (Hex) has been widely used in agricultural products, and its residues may pose a potential risk to human health. However, the metabolic behavior of Hex enantiomers in mammal organisms is still unknown, which is important for evaluating the ...
Guofei Luo, Junxiao Pang, Dali Sun, Qinghai Zhang   +3 more
doaj   +1 more source

Predicting glycosylation stereoselectivity using machine learning

Chemical Science, 2020
Predicting the stereochemical outcome of chemical reactions is challenging in mechanistically ambiguous transformations. The stereoselectivity of glycosylation reactions is influenced by at least eleven factors across four chemical participants and ...
Sooyeon Moon, S. Chatterjee, P. Seeberger, K. Gilmore   +3 more
semanticscholar   +1 more source

Synthesis of Polysubstituted Ferrocenesulfoxides

Molecules, 2022
The purpose of the study is to design synthetic methodologies, especially directed deprotometalation using polar organometallic reagents, to access polysubstituted ferrocenesulfoxides.
Min Wen, William Erb, Florence Mongin, Yury S. Halauko, Oleg A. Ivashkevich, Vadim E. Matulis, Thierry Roisnel   +6 more
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Stereoselective Synthesis of Microcarpalide. [PDF]

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Juan, Murga, Eva, Falomir, Jorge, García-Fortanet, Miguel, Carda, J Alberto, Marco   +4 more
openaire   +2 more sources

Tetrahydropyridines’ Stereoselective Formation, How Lockdown Assisted in the Identification of the Features of Its Mechanism

Molecules, 2022
The multicomponent reaction of aldehydes, cyano-containing C-H acids, esters of 3-oxocarboxylic acid and ammonium acetate led to unexpected results.
Anatoly N. Vereshchagin, Taigib M. Iliyasov, Kirill A. Karpenko, Radmir N. Akchurin, Mikhail E. Minyaev   +4 more
doaj   +1 more source

Stereoselective Synthesis of (−)-Spicigerolide [PDF]

The Journal of Organic Chemistry, 2009
(-)-Spicigerolide was stereoselectively synthesized from a protected (S)-lactaldehyde. The synthesis of the polyacetylated framework relied on two Zn-mediated stereoselective additions of alkynes to aldehydes as well as a regiocontrolled [3,3]-sigmatropic rearrangement of an allylic acetate.
Georges, Yohan, Ariza Piquer, Xavier, García Gómez, Jordi   +2 more
openaire   +3 more sources

In pursuit of β-amino α-nitro β-trifluoromethyl ketones: nitro-Mannich vs Mannich-type reactions [PDF]

, 2017
The reactivity of alfa-nitro ketones with trifluoromethyl aldimines is studied for the first time. While under nitro-Mannich conditions only the facial stereoselectivity can be controlled, organocatalysed Mannich-type reactions allowed a complete control
Ballini, Ballini, Ballini, Ballini, Bhadury, Carroccia, Carroccia, Chen, Claridge, Córdova, Dighe, Dinér, Donslund, Fioravanti, Fioravanti, Fioravanti, Fioravanti, Fioravanti, Gao, Ghosh, Hatano, Hurd, Ibrahem, Ilies, Kano, Kano, Kelly, Kobayashi, Kokotos, Levy, Merino, Mitsumori, Moteki, Nguyen, Nie, Noble, Parise, Parise, Pelagalli, Stach, Walaszek, Yang, Yin, Zhang, Zhang, Zheng   +45 more
core   +1 more source

A Simple Nickel Catalyst Enabling an E‐Selective Alkyne Semihydrogenation [PDF]

, 2019
Stereoselective alkyne semihydrogenations are attractive approaches to alkenes, which are key building blocks for synthesis. With regards to the most atom economic reducing agent dihydrogen (H 2 ), only few catalysts for the challenging E ‐selective ...
Kaewmee, Benyapa, Teichert, Johannes F., Thiel, Niklas Olof, Tran Ngoc, Trung   +3 more
core   +1 more source

Analysis of chiral non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac binding with HSA

Journal of Pharmaceutical Analysis, 2011
The protein binding of non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac with human serum albumin (HSA) was investigated using indirect chiral high performance liquid chromatography (HPLC) and ultrafiltration techniques. S-(–)-
Chang-Chuan Guo, Yi-Hong Tang, Hai-Hong Hu, Lu-Shan Yu, Hui-Di Jiang, Su Zeng   +5 more
doaj   +1 more source