Results 51 to 60 of about 168,162 (295)
MoleculesAntisense inhibition of gene expression is usually achieved using nuclease-resistant oligonucleotide analogs that promote mRNA degradation through RNase H or RNase P, or by steric hindrance of translation.
Angel J. Magaña +4 more
doaj +1 more source
Immunoglobulin G‑Based Steric Hindrance Assay for Protein Detection
, 2019 With the imminent needs of rapid, accurate, simple point-of-care systems for global healthcare industry, electrochemical biosensors have been widely developed owing to their cost-effectiveness and simple instrumentation.
Chung Chiun Liu (5394020) +5 more
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Kinetic Parameters of Biomass Pyrolysis by TGA
BioResources, 2016 Pyrolysis processes of typical biomass, such as corn stalk and birch chips, were investigated by thermogravimetric analysis (TGA). The apparent activation energy and pre-exponential factor were calculated with the adoption of the improved Coats-Redfern ...
Ming Zhai +5 more
doaj +1 more source
APL Energy, 2023 All-polymer solar cells (all-PSCs) have attracted enormous attention and achieved significant progress in recent years due to their long-term stability and excellent film stretchability.
Mengzhen Sha +6 more
doaj +1 more source
Effect of Alkyl Side Chain Length on the Lithium-Ion Conductivity for Polyether Electrolytes
Frontiers in Chemistry, 2022 The design guidelines of polymer structure to effectively promote lithium-ion conduction within the polymer electrolytes (PEs) are crucial for its practical use.
Ryansu Sai +4 more
doaj +1 more source
Large Steric Hindrance Enhanced Molecular Planarity for Low-Cost Non-Fused Electron Acceptors
, 2023 Designing efficient non-fused ring electron acceptors is of great importance in decreasing the material cost of organic photovoltaic cells (OPVs).
Yang Xiao (146335) +12 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Interfacial assignment of branched-alkyl benzene sulfonates: A molecular simulation
AIP Advances, 2015 A molecular dynamics simulation was conducted to analyze orientations of sodium branched-alkyl benzene sulfonates molecules at nonane/water interface, which is helpful to design optimal surfactant structures to achieve ultralow interfacial tension (IFT).
Zi-Yu Liu +6 more
doaj +1 more source