Results 131 to 140 of about 43,028 (255)

Integrative Transcriptomic Analysis and Functional Validation Implicate GPT2 in Glycolytic Regulation in Polycystic Ovary Syndrome

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Integrating GEO transcriptomic datasets, machine‐learning algorithms, GSVA, multilayer regulatory network and immune infiltration analyses, this study revealed metabolic‐immune disturbance and aberrant ovarian steroidogenesis in polycystic ovary syndrome (PCOS).
Meili Xi, Rongkui Luo, Jiarong Zhang, Weihong Huang, Li Ma, Yunyan Sun, Aimin Ren   +6 more
wiley   +1 more source

ANDROGEN BIOSYNTHESIS BY THE RAT PLACENTA (STEROIDOGENESIS, ANDROSTENEDIONE).

, 1986
ANDROGEN BIOSYNTHESIS BY THE RAT PLACENTA (STEROIDOGENESIS, ANDROSTENEDIONE)
MEREDITH LOUISE. WARSHAW (7985816)
core   +2 more sources

Bushen Huatan Formula Ameliorates Early Chronic Low‐Grade Inflammation in Obese PCOS Via the TLR4/NF‐κB Signaling Pathway: An Integrated Network Pharmacology and Experimental Study

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
ABSTRACT Objective This study used an integrated network pharmacology and experimental strategy to investigate how Bushen Huatan Formula (BHF) mitigates early‐stage chronic low‐grade inflammation in obese polycystic ovary syndrome (PCOS). Methods Candidate components and targets of BHF were retrieved from the TCMSP database, and protein–protein ...
Jianing Zhang, Fangyun Gu, Yunyun Li, Xiaoling Feng, Hongying Kuang, Fang Xu, Miao Sun   +6 more
wiley   +1 more source

Calcium inhibits ovarian steroidogenesis in the blowfly, Phormia regina

, 2002
1479-6805 0022-0795Calcium is frequently involved in the stimulation of steroidogenesis in gonads and endocrine glands, generally in association with cAMP. However, our present observations show that it has the opposite effect in the ovary of the blowfly
Delbecque, Jean-Paul, Manière, Gérard, Gautron, F., Vanhems, E.   +3 more
core   +1 more source

A uterine‐centric view of reproductive senescence: Genetic insights into late‐life performance in laying hens

iMetaOmics, Volume 3, Issue 3, September 2026.
This study identifies uterus weight as a heritable (h2 = 0.45) intermediate phenotype that independently associates with late‐life egg production and eggshell quality in aged laying hens. Genome‐wide association study (GWAS) reveals a genome‐wide significant locus on chromosome 3 and suggestive loci on chromosome 11 for uterus weight, mediation ...
Junnan Zhang, Mingyue Gao, Ronglang Cai, Xinwei Jiang, Boxuan Zhang, Zhaojie Li, Ning Yang, Congjiao Sun   +7 more
wiley   +1 more source

Recent advances and clinical applications of 3D printing for female reproductive organ regeneration and gynecological disease

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley   +1 more source

Of the Many Secrets of Steroidogenesis

Biology of Reproduction, 2012
Charles L, Chaffin, Rebecca S, Brogan
openaire   +2 more sources

Effects of fluorotelomer alcohol 8/2 FTOH on steroidogenesis in H295R cells: Targeting the cAMP signalling cascade

, 2010
Previous studies have demonstrated that perfluorinated chemicals (PFCs) can affect reproduction by disruption of steroidogenesis in experimental animals. However, the underlying mechanism(s) of this disruption remain unknown.
Zhou, Bingsheng, Giesy, John P., Zhang, XW, Nanjing Univ, Sch Environm, Nanjing 210089, Peoples R China, Zhang, Xiaowei, Chang, Hong, Liu, Chunsheng, Wiseman, Steve, Hecker, Markus, Naile, Jonathan, Jones, Paul   +9 more
core  

Fisetin Attenuates Uterine Leiomyoma in Rats: Potential Crosstalk Between HMGB1, SphK1/S1P, and TGF‐β Signaling

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Fisetin attenuates monosodium glutamate‐induced uterine leiomyoma by reducing sex hormones and suppressing S1P/SphK1 signaling, HMGB1‐mediated inflammation, and fibrotic markers. These coordinated effects alleviate fibrosis and restore uterine tissue architecture, highlighting fisetin as a promising natural therapeutic candidate.
Nashwa Maghraby, Esraa Khalaf, Marwa T. Hussien, Ahmed M. A. Sobh, Nagla T. Elmelegy   +4 more
wiley   +1 more source

Therapeutic Potential of Chickpea‐Derived Bioactives: A Review With Perspective of Different In Vitro, Animal, and Human Studies

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid, Maria Maqsood, Nimrah Ashraf, Farzeen Asghar, Nauman Khalid   +4 more
wiley   +1 more source