Results 141 to 150 of about 43,028 (255)

Effect of conazoles on steroidogenesis mapped by extended H295R-CALUX® assay and LC-MS/MS profiling. [PDF]

NAM J
Budin C, Berkenveld K, Islam B, Brouwer A, de Boer T.   +4 more
europepmc   +1 more source

Metabolism in Tumor: Mechanisms and Therapeutic Perspectives

MedComm, Volume 7, Issue 9, September 2026.
Tumor metabolic reprogramming converges on three hubs—the SREBP1/2–FASN–SCD1 lipogenic axis, the HIF‐1α–GLUT1–LDHA glycolytic axis, and the LDLR–SCARB1–LXR cholesterol system—which integrate transcriptional, epigenetic (histone lactylation, m6A), and microenvironmental inputs to generate metabolic plasticity, immune evasion, and therapy resistance ...
Jia‐Chen Cheng, Yi‐Xuan Hu, Xiang‐Chun Huang, Shan Jiang, Jie‐Lin Wang, Yang Zhao, Shuo Chen   +6 more
wiley   +1 more source

The essential role of the redox balance in adrenal steroidogenesis. [PDF]

Arch Endocrinol Metab
Gebenlian JL, Bodoni AF, Coeli-Lacchini FB, Castro M, Antonini SRR.   +4 more
europepmc   +1 more source

Amino Acid Metabolism in Health and Disease

MedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su, Jinyu Liu, Xiaoliang Deng, Yanqun Luo, Haiping Xue, Lei Wang, Lianjun Xing, Tao Wu   +7 more
wiley   +1 more source

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

Environmental Toxicology, Volume 41, Issue 9, Page 709-729, September 2026.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó, Luís P. Brás, Catarina M. D. Serra, Lara R. S. Fonseca, Sara Correia, Bruno J. Pereira, Ana P. Duarte, Henrique J. Cardoso, Cátia V. Vaz, Sílvia Socorro   +9 more
wiley   +1 more source

Trimester Specific Anatomical and Histological Characterization of Testicular Descent and Development in Sheep Foetuses

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study illustrates trimester‐specific testicular descent and development in Hamdani crossbred sheep foetuses. Macroscopic, morphometric, histological and SEM findings show progressive migration toward the scrotum, significant testicular growth, seminiferous cord organization, interstitial maturation and cellular differentiation, establishing a ...
Barış Can Güzel, Banu Kandil, Muhammet Zahid Atli, İhsan Işbilir, Oleksii O. Melnyk, Fatma Işbilir   +5 more
wiley   +1 more source

Multi-omics reveals that dietary arachidonic acid reshapes hepatopancreatic lipid remodeling and modulates steroidogenesis-related pathways in mud crab. [PDF]

Food Chem (Oxf)
Fang F, Yuan Y, Jin M, Wang X, Zhu T, Zhou Q.   +5 more
europepmc   +1 more source

Growth Hormone Reverses Cisplatin‐Induced Ovarian Reserve Depletion in Mice: Transcriptomic Elucidation of Mitochondrial Metabolic Reprogramming and Protein Synthesis Regulation

FASEB BioAdvances, Volume 8, Issue 9, September 2026.
This study investigated the effects of different doses of growth hormone (GH) on cisplatin (CDDP)‐induced ovarian injury and the underlying mechanisms in female Kunming mice. First, a diminished ovarian reserve (DOR) model was established by intraperitoneal injection of 1.5 mg/kg CDDP for 7 consecutive days.
Tianhong Huang, Niu Wang, Dongsheng Xiong, Yanan Zhang, Jiajing Wei, Furui Chen, Yu Qiu, Fangyi Long, Qianwen Luo, Jesse Li‐Ling, Yan Gong   +10 more
wiley   +1 more source

Neuroendocrine Disruption of Reproduction by Bisphenols and Phthalates: From Molecular Mechanisms to Reproductive Outcomes. [PDF]

Int J Mol Sci
Gherman Lencu CC, Gerdanovics CA, Orășan OH, Iancu DM, Gerdanovics A, Perne MG, Milaciu MV, Negrean V, Dobrotă IR, Alexescu TG.   +9 more
europepmc   +1 more source

Mitochondrial Haplotype Shapes the Trajectory of Ovarian Aging in Genetically Heterogeneous Rats

Aging Cell, Volume 25, Issue 9, September 2026.
Using genetically heterogeneous rats carrying divergent mitochondrial haplotypes on a randomized nuclear background, we show that mtDNA variation modifies the rate of ovarian aging. OKC‐HETW ovaries showed bioenergetic deficits, reduced mtDNA copy number, and impaired TFAM–mtDNA binding by 4 months of age, with early fibrosis and immune infiltration ...
Subhasri Biswas, Hoang V. M. Nguyen, Aubrey Converse, Satoshi Matsuzaki, Michael T. Kinter, Kenneth M. Humphries, Willard M. Freeman, Sarah R. Ocañas, Arlan Richardson, Francesca E. Duncan, Tommy L. Lewis Jr, Michael B. Stout   +11 more
wiley   +1 more source