FDA regulatory approach to steviol glycosides
Food and Chemical Toxicology, 2018 Stevia rebaudiana (Bertoni) Bertoni, commonly known as stevia, is a plant native to South America that has been cultivated for hundreds of years. In 1995, FDA revised its import alert on stevia leaves and extracts to allow for their use as dietary ingredients in dietary supplements.
Judith D, Perrier +2 more
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Enhancement of diterpenoid steviol glycosides by co-overexpressing SrKO and SrUGT76G1 genes in Stevia rebaudiana Bertoni. [PDF]
PLoS ONE, 2023 Stevia rebaudiana (stevia) contains commercially important steviol glycosides, stevioside and rebaudioside A, these compounds have insulinotropic and anti-hyperglycemic effect.
Nazima Nasrullah +7 more
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Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides [PDF]
Nature Communications, 2021 Steviol glycosides from the plant Stevia rebaudiana are already used as lowcalorie sweeteners, but the most abundant naturally occurring compounds have a bitter aftertaste. Here, the authors characterize and engineer rice glycosyltransferase OsUGT91C1 to
Jinzhu Zhang +13 more
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Journal of Environmental Chemical Engineering, 2021 Abstract Steviol glycosides are fully deglycosylated to steviol in the presence of bacterial populations that were isolated from different soil samples. Heating (20 min at 80 °C) or boiling (10 min at 100 °C) of soils had little effect on the steviol formation.
Boudewijn Meesschaert +2 more
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Scientific opinion on the extension of the authorisation of use of the food additive steviol glycosides (E 960a–d) and the modification of the acceptable daily intake (ADI) for steviol [PDF]
EFSA JournalThe EFSA Panel on Food Additive and Flavourings (FAF Panel) evaluated the safety of proposed changes to the currently permitted uses of the food additive steviol glycosides (E 960a–d) and of a proposed modification of the current acceptable daily intake (
EFSA Panel on Food Additives and Flavourings (FAF) +29 more
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Progress on Synthetic Biology for Steviol Glycosides Biosynthesis
Shipin gongye ke-jiStevioside, also known as stevia, is a class of diterpenoids extracted from stevia with high sweetness, low calories, safety and non-toxicity, hypoglycemic, hypotensive, and other physiological characteristics.
Mengyu LIU +7 more
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Improving Steviol Glycosides Production in Stevia Rebaudian Bertoni by Plant Tissue Culture Technology" [PDF]
مجلة جامعة كركوك للعلوم الزراعية, 2023 Plant tissue culture techniques have made tremendous progress in the production of various active compounds of interest, including Steviol Glycosides in Stevia.
Suhad Mahdi, Noora Alsaedi
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Bioconversion of steviol glycosides into steviol by Microbacterium barkeri [PDF]
Journal of Asian Natural Products Research, 2020 The strain which degraded steviol glycosides to steviol (STE) was screened and isolated from soil samples. A phylogenetic tree was constructed and used to determine the taxonomic status of the strain. 16S rDNA sequence was ultimately used to identify the strain as Microbacterium barkeri XJ.
Jiang, Hui-Ling +8 more
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Phytomedicine Plus, 2022 Background: Steviol glycosides, constituents of Stevia rebaudiana Bertoni, are high-intensity sweeteners that enhance glucose-induced insulin secretion and decrease hyperglycemia in mice and rats.
Caroline Simoens +9 more
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Safety in use of glucosylated steviol glycosides as a food additive in different food categories
EFSA Journal, 2018 The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion on the safety of glucosylated steviol glycosides proposed for use as a new food additive in different food categories.
EFSA Panel on Food Additives and Nutrient Sources added to Food (EFSA ANS Panel) +24 more
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