Results 111 to 120 of about 10,398 (215)
MedCommMetastasis is the leading cause of death in hepatocellular carcinoma (HCC) patients, and autophagy plays a crucial role in this process by orchestrating epithelial–mesenchymal transition (EMT).
Jingchun Wang +10 more
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STIM1 Mediates Hypoxia-Driven Hepatocarcinogenesis via Interaction with HIF-1
Cell Reports, 2015 Hypoxia and intracellular Ca2+ transients are fundamental traits of cancer, whereas the route and regulation of Ca2+ mobilization in hypoxic tumorigenesis are unknown.
Yongsheng Li +7 more
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STIM1 mediates multiple signalling pathways in neuronal growth cones
, 2014 Calcium is an intracellular second messenger that is vital for normal neuronal function. The maintenance of calcium homeostasis is critical for healthy neuronal function, and disruption in calcium homeostasis has been implicated in diseases such as ...
Mitchell, CB (15932324)
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STIM1 for stimulation of phagocyte NADPH oxidase
Blood, 2014 In this issue of Blood, Zhang et al show that mice lacking the stromal-interacting molecule 1 (STIM1) gene in bone marrow cells are more susceptible to bacterial infection but are resistant to ischemia/reperfusion injury because of defective activation of phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase.
openaire +3 more sources
CHARACTERIZATION OF THE ROLE OF STIM1 IN MELANOGENESIS
, 2023 reservedIntracellular Ca2+ homeostasis plays a key role in the control of melanogenesis, the process responsible for the biogenesis of melanosomes, and for melanin accumulation.
DE CIA, ISABELLA
core
Linchuang shenzangbing zazhiObjectiveTo explore the serum expressions of stromal interaction molecule 1 (STIM1) and retinol binding protein 4 (RBP4) in patients with hypertensive nephropathy (HN) and examine their diagnostic values.[(375.53±71.41)μmol/Lvs(342.80±59.75)μmol/L、(352 ...
Lin Zhou, Jing Li, Yi Li, Ming Zhao
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Regulation of STIM1 by O-GlcNAcylation in Cardiomyocytes [PDF]
, 2013 In non-excitable cells, STIM1 and Orai1 are the primary mediators of store-operated Ca2+ entry (SOCE); however little is known about their roles in cardiomyocyte Ca2+ handling.
Zhu-Mauldin, Xiaoyuan
core
, 2017 International audienceCalcium is involved in important intracellular processes, such as intracellular signaling from cell membrane receptors to the nucleus.
Debant, Marjolaine +7 more
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The regulation of STIM1 translocation to the plasma membrane
, 2010 A rise in intracellular Ca2+ concentration is key to controlling both short term and long term Ca2+ dependent processes which include secretion, metabolism and gene expression, cell growth and proliferation. Store operated Ca2+ channels (SOCs), which are
Walsh, Ciara +2 more
core
, 2012 Part A: HEK293T cells were cotransfected with VN173-ST1, VC155-ST1 and mCh-STIM1 constructs. Live cells were examined under a confocal microscope at the cell footprint.
Jingying Pan (176967) +3 more
core +1 more source