Results 91 to 100 of about 7,759 (184)

Stromal interaction molecule 1/microtubule‐associated protein 1A/1B‐light chain 3B complex induces metastasis of hepatocellular carcinoma by promoting autophagy

MedComm
Metastasis is the leading cause of death in hepatocellular carcinoma (HCC) patients, and autophagy plays a crucial role in this process by orchestrating epithelial–mesenchymal transition (EMT).
Jingchun Wang, Qichao Xie, Lei Wu, Yu Zhou, Yanquan Xu, Yu Chen, Jiangang Zhang, Ran Ren, Shiming Yang, Yongsheng Li, Huakan Zhao   +10 more
doaj   +1 more source

STIM1 for stimulation of phagocyte NADPH oxidase

Blood, 2014
In this issue of Blood, Zhang et al show that mice lacking the stromal-interacting molecule 1 (STIM1) gene in bone marrow cells are more susceptible to bacterial infection but are resistant to ischemia/reperfusion injury because of defective activation of phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase.
openaire   +3 more sources

Diagnostic values of serum levels of stromal interaction molecule 1 and retinol binding protein 4 in patients with hypertensive nephropathy

Linchuang shenzangbing zazhi
ObjectiveTo explore the serum expressions of stromal interaction molecule 1 (STIM1) and retinol binding protein 4 (RBP4) in patients with hypertensive nephropathy (HN) and examine their diagnostic values.[(375.53±71.41)μmol/Lvs(342.80±59.75)μmol/L、(352 ...
Lin Zhou, Jing Li, Yi Li, Ming Zhao
doaj   +1 more source

Loss of STIM1 and STIM2 in Salivary Glands Disrupts ANO1 Function but Does Not Induce Sjogren’s Disease

Function
Ca2+ signaling via the store-operated Ca2+ entry (SOCE) mediated by STIM1 and STIM2 proteins and the ORAI1 Ca2+ channel is important in saliva fluid secretion and has been associated with Sjogren’s disease (SjD).
Ga-Yeon Son, Anna Zou, Amanda Wahl, Kai Ting Huang, Saruul Zorgit, Manikandan Vinu, Fang Zhou, Larry Wagner, Youssef Idaghdour, David I Yule, Stefan Feske, Rodrigo S Lacruz   +11 more
doaj   +1 more source

STIM1, ORAI1, and KDM2B in circulating tumor cells (CTCs) isolated from prostate cancer patients

Frontiers in Cell and Developmental Biology
Introduction: Previous publications have shown that STIM1, ORAI1, and KDM2B, are implicated in Ca2+ signaling and are highly expressed in various cancer subtypes including prostate cancer.
Argyro Roumeliotou, Saad Alkahtani, Saud Alarifi, Abdullah A. Alkahtane, Christos Stournaras, Galatea Kallergi   +5 more
doaj   +1 more source

STIM1 Gene [PDF]

, 2020
openaire   +1 more source

The D84G mutation in STIM1 causes nuclear envelope dysfunction and myopathy in mice

The Journal of Clinical Investigation
Stromal interaction molecule 1 (STIM1) is a Ca2+ sensor located in the sarcoplasmic reticulum (SR) of skeletal muscle, where it is best known for its role in store-operated Ca2+ entry (SOCE).
Victoria Bryson, Chaojian Wang, Zirui Zhou, Kavisha Singh, Noah Volin, Eda Yildirim, Paul Rosenberg   +6 more
doaj   +1 more source

STIM1 GoF Mutants: Genotype-Phenotype Relationships Across the Stormorken/TAM/YPS Spectrum. [PDF]

Cells
Atzgerstorfer L, Prantl M, Waldhauser A, Derler I, Fahrner M.   +4 more
europepmc   +1 more source

Unraveling new functions of the Ca2+ sensor STIM1 in cell signaling. [PDF]

Biochem Soc Trans
Sanchez-Lopez I, Orantos-Aguilera Y, Lopez-Guerrero AM, Pozo-Guisado E, Martin-Romero FJ.   +4 more
europepmc   +1 more source

STIM/Orai-Mediated Store-Operated Ca²⁺ Entry in the Pathogenesis of Fibrosis: Mechanisms and Therapeutic Opportunities. [PDF]

Cells
Yi Y, Uddin MN, Killeen K, Gill DL, Zhou Y.   +4 more
europepmc   +1 more source