Results 11 to 20 of about 61,886,207 (255)

Tumour–stroma interactions in an organotypic culture model of pancreatic cancer [PDF]

, 2011
PhDPancreatic cancer is characterised by an intense fibrotic, or desmoplastic, stroma, which contributes to tumour progression. Three-dimensional in vitro culture models incorporating this non-tumour component may more closely recapitulate the ...
Froeling, Fieke E.M.
core   +4 more sources

1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes. [PDF]

, 1996
1,25 (OH)(2) Vitamin D-3 (VD3) and retinoic acid (RA) function as ligands for nuclear receptors which regulate transcription, Though the cardiovascular system is not thought to represent a classical target for these ligands, it is clear that both cardiac
Gardner, D. G., J Wu, Garami, Miklós, Cheng, T., T Cheng, Wu, J., M Garami, D G Gardner   +7 more
core   +1 more source

Adaptive evolution of the STRA6 genes in mammalian. [PDF]

PLoS ONE, 2014
Stimulated by retinoic acid 6 (STRA6) is the receptor for retinol binding protein and is relevant for the transport of retinol to specific sites such as the eye.
Jianghong Wu, Hui Xiang, Yunxia Qi, Ding Yang, Xiaojuan Wang, Hailian Sun, Feng Wang, Bin Liu   +7 more
doaj   +1 more source

Tripterine and all-trans retinoic acid (ATRA) – loaded lipid-polymer hybrid nanoparticles for synergistic anti-arthritic therapy against inflammatory arthritis

Artificial Cells, Nanomedicine, and Biotechnology, 2021
Arthritis of joints remains a hard-to-treat disease due to the low drug exposure to the articular cavity. Present study was intended to develop a Tripterine (TRI) and all-trans retinoic acid (ATRA)-loaded lipid-polymer hybrid nanoparticles (ATLP) for ...
Jichao Li, Zeng Zhang, Xiaohan Huang
doaj   +1 more source

Identification of genes involved in inbreeding depression of reproduction in Langshan chickens [PDF]

Animal Bioscience, 2021
Objective Inbreeding depression of reproduction is a major concern in the conservation of native chicken genetic resources. Here, based on the successful development of strongly inbred (Sinb) and weakly inbred (Winb) Langshan chickens, we aimed to ...
Qian Xue, Guohui Li, Yuxia Cao, Jianmei Yin, Yunfen Zhu, Huiyong Zhang, Chenghao Zhou, Haiyu Shen, Xinhong Dou, Yijun Su, Kehua Wang, Jianmin Zou, Wei Han   +12 more
doaj   +1 more source

FGF and retinoic acid activity gradients control the timing of neural crest cell emigration in the trunk [PDF]

, 2011
Coordination between functionally related adjacent tissues is essential during development. For example, formation of trunk neural crest cells (NCCs) is highly influenced by the adjacent mesoderm, but the molecular mechanism involved is not well ...
Quiroga, Alejandra C, Kate G. Storey, Barbas, Julio A., Storey, Kate G, Morales, Aixa V., Alejandra C. Quiroga, Storey, Kate G., Das, R. M., Quiroga, Alejandra C., Barbas, Julio A, Aixa V. Morales, Raman M. Das, Das, Raman M., Morales, Aixa V, Olivera-Martinez, Isabel, Ruth Diez del Corral, Patricia L. Martínez-Morales, Julio A. Barbas, Martinez-Morales, Patricia L., Olivera-Martínez, I., Isabel Olivera-Martínez, Martínez-Morales, Patricia L, Diez del Corral, Ruth, Das, Raman M; id_orcid   +23 more
core   +1 more source

Pathogenesis of retinoic acid-induced spina bifida in rat embryos [PDF]

, 2008
In a previous study, we showed that the intrauterine exposure of rat embryos to retinoic acid (RA) in the organogenesis period (8-11 days of gestation) induced various malformations according to the dose and timing of RA administration.
コニシ, ヒロヨシ, 小西, 啓悦, 1430, Konishi, Hiroyoshi   +3 more
core   +1 more source

Electronegative low density lipoprotein induces renal apoptosis and fibrosis: STRA6 signaling involved[S]

Journal of Lipid Research, 2016
Dyslipidemia has been proven to capably develop and aggravate chronic kidney disease. We also report that electronegative LDL (L5) is the most atherogenic LDL.
Chao-Hung Chen, Liang-Yin Ke, Hua-Chen Chan, An-Sheng Lee, Kun-Der Lin, Chih-Sheng Chu, Mei-Yueh Lee, Pi-Jung Hsiao, Chin Hsu, Chu-Huang Chen, Shyi-Jang Shin   +10 more
doaj   +1 more source

Phospholipase C-η2 interacts with nuclear and cytoplasmic LIMK-1 during retinoic acid-stimulated neurite growth [PDF]

, 2015
We gratefully acknowledge financial support from the Wellcome Trust (Grant No. WT089803MA to J.M.L.) and the School of Medicine, University of St Andrews.Neurite growth is central to the formation and differentiation of functional neurons and recently ...
Mohammed Arastoo, John M. Lucocq, Hacker, Christian, Lucocq, John Milton, Arastoo, Mohammed, Popovics, Petra, Stewart, Alan J., Christian Hacker, Alan J. Stewart, Petra Popovics   +9 more
core   +1 more source

Retinol and vitamin A metabolites accumulate through RBP4 and STRA6 changes in a psoriasis murine model

Nutrition & Metabolism, 2020
Background Psoriasis is a common chronic inflammatory skin disease that features the abnormal proliferation of keratinocytes. This proliferation could partly result from disturbances in vitamin A metabolism. Changes in psoriasis patients of the levels of
Hai-meng Wang, Chao Wu, Yan-yun Jiang, Wen-ming Wang, Hong-zhong Jin   +4 more
doaj   +1 more source