Results 21 to 30 of about 61,886,207 (255)

In vitro epigenetic reprogramming of human cardiac mesenchymal stromal cells into functionally competent cardiovascular precursors [PDF]

, 2012
Adult human cardiac mesenchymal-like stromal cells (CStC) represent a relatively accessible cell type useful for therapy. In this light, their conversion into cardiovascular precursors represents a potential successful strategy for cardiac repair.
Andrea Barbuti (106295), A. Barbuti, Rossini, Alessandra, Simona Nanni, Nanni, Simona, Barbuti, Andrea, C. Gaetano, Meraviglia Viviana, Carlo Gaetano (110837), Meraviglia, Viviana, Capogrossi, Maurizio C., Pompilio Giulio, Gualtiero I Colombo, Angela Scavone, Simona Nanni (110816), Maurizio C Capogrossi, S. Nanni, Scavone Angela, Matteo Vecellio, Viviana Meraviglia (110811), DiFrancesco Dario, A. Scavone, Antonella Farsetti, Alessandra Rossini (110841), Viviana Meraviglia, Colombo Gualtiero I., Dario DiFrancesco, Pompilio, Giulio, Gaetano, Carlo, Vecellio, Matteo, Nanni Simona, Maurizio C. Capogrossi (103525), D. DiFrancesco, Giulio Pompilio (103510), Gaetano Carlo, Carlo Gaetano, Colombo, Gualtiero I., Vecellio Matteo, Farsetti Antonella, A. Farsetti, Angela Scavone (110822), M. Vecellio, Farsetti, Antonella, Barbuti Andrea, Capogrossi Maurizio C., Rossini Alessandra, G.I. Colombo, Giulio Pompilio, Antonella Farsetti (110827), V. Meraviglia, Alessandra Rossini, Andrea Barbuti, DiFrancesco, Dario, Dario DiFrancesco (106304), M. C. Capogrossi, Gualtiero I. Colombo (103516), Scavone, Angela, Matteo Vecellio (110807), A. Rossini, G. Pompilio   +59 more
core   +2 more sources

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Synthesis of α1-microglobulin in cultured rat hepatocytes is stimulated by interleukin-6, leukemia inhibitory factor, dexamethasone and retinoic acid [PDF]

, 1992
The secretion or α1-microglobulin by primary cultures of rat hepatocytes was found to increase upon the addition of interleukin-6 or leukemia inhibitory factor, two mediators of acute phase response.
Pierzchalski, P, Fries, Erik, Aleksander Koj, Piotr Pierzchalski, Hanna Rokita, Rokita, H, Koj, A, Fries, E, Pierzchalski, Piotr, Koj, Aleksander, Rokita, Hanna, Bo Åkerström, Akerström, B, Åkerström, Bo, Erik Fries   +14 more
core   +1 more source

The Expression of Bone Morphogenetic Protein 2 and Matrix Metalloproteinase 2 through Retinoic Acid Receptor Beta Induced by All-Trans Retinoic Acid in Cultured ARPE-19 Cells.

PLoS ONE, 2016
PurposeAll-trans retinoic acid (ATRA) plays an important role in ocular development. Previous studies found that retinoic acid could influence the metabolism of scleral remodeling by promoting retinal pigment epithelium (RPE) cells to secrete secondary ...
Zhenya Gao, Lijun Huo, Dongmei Cui, Xiao Yang, Junwen Zeng   +4 more
doaj   +1 more source

Targeting the acute promyelocytic leukemia-associated fusion proteins PML/RARα and PLZF/RARα with interfering peptides [PDF]

, 2012
In acute promyelocytic leukemia (APL), hematopoietic differentiation is blocked and immature blasts accumulate in the bone marrow and blood. APL is associated with chromosomal aberrations, including t(15;17) and t(11;17).
Sabine Beez (123610), Beez, Sabine, Philipp Demmer, Elena Puccetti (66633), Philipp Demmer (123611), Puccetti, Elena, Elena Puccetti, Sabine Beez, Demmer, Philipp   +8 more
core   +1 more source

O-GlcNAc-Mediated Regulation of Galectin Expression and Secretion in Human Promyelocytic HL-60 Cells Undergoing Neutrophilic Differentiation

Biomolecules, 2022
In this study, we have tested the hypothesis that the expression and secretion of galectins are driven through mechanisms globally impacted by homeostatic regulation involving the post-translational modification of intracellular proteins with O-linked N ...
Adam McTague, Rada Tazhitdinova, Alexander V. Timoshenko   +2 more
doaj   +1 more source

Inter-α-Inhibitor Impairs TSG-6-Induced Hyaluronan Cross-Linking [PDF]

, 2013
Under inflammatory conditions and in the matrix of the cumulus-oocyte complex (COC), the polysaccharide hyaluronan (HA) becomes decorated covalently with heavy chains (HCs) of the serum glycoprotein inter-α-inhibitor (IαI).
Briggs, David C., Richter, Ralf P., Day, Anthony J., Ralf P. Richter, Baranova, Natalia, Viranga Tilakaratna, Day, Anthony J.; id_orcid, David C. Briggs, Natalia S. Baranova, Tilakaratna, Viranga, Enghild, Jan J., Caroline M. Milner, Baranova, Natalia S., Jan J. Enghild, Milner, Caroline M., Foulcer, Simon J., Simon J. Foulcer, Anthony J. Day   +17 more
core   +1 more source

Retinoic Acid Induces Functionally Suppressive Foxp3+RORγt+ T Cells In Vitro

Frontiers in Immunology, 2021
IntroductionCD4+ T cells with regulatory function co-expressing Foxp3 and RORγt are linked to the development of oral tolerance towards innocuous food antigens in mice.
Mónica Martínez-Blanco, Daniel Lozano-Ojalvo, Leticia Pérez-Rodríguez, Sara Benedé, Elena Molina, Rosina López-Fandiño   +5 more
doaj   +1 more source

The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer [PDF]

, 2014
Peer ...
Petronella Johansson, Johansson, Petronella, Gordon T Brown, Gordon T. Brown (532127), Beatriz Gimenez Cash, Beatriz Gimenez Cash (532128), Ayham Alnabulsi (532130), Graeme I. Murray (195455), Daniela Blihoghe, Cash, Beatriz Giminez, Alnabulsi, Ayham, Daniela Blihoghe (472704), Brown, Gordon T, Graeme I Murray, Ayham Alnabulsi, Petronella Johansson (532129), Blihoghe, Daniela, Murray, Graeme I   +17 more
core   +2 more sources

Pentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma

npj Precision Oncology, 2021
Pancreatic ductal adenocarcinoma (PDAC), characterized by dense desmoplastic stroma laid down by pancreatic stellate cells (PSC), has no reliable diagnostic biomarkers for timely detection.
Michelle R. Goulart, Jennifer Watt, Imran Siddiqui, Rita T. Lawlor, Ahmet Imrali, Christine Hughes, Amina Saad, Joanne ChinAleong, Chris Hurt, Catrin Cox, Roberto Salvia, Alberto Mantovani, Tatjana Crnogorac-Jurcevic, Somnath Mukherjee, Aldo Scarpa, Paola Allavena, Hemant M. Kocher   +16 more
doaj   +1 more source