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Ca2+ ionophores trigger membrane remodeling without a need for store-operated Ca2+ entry

Biochemical and Biophysical Research Communications, 2005
Calcium (Ca2+) ionophores are the most effective agents able to elicit rapid membrane remodeling in vitro. This process exposes aminophospholipids at the surface of platelets and blood cells, thus providing a catalytic surface for coagulation. To explore the underlying mechanism, we examined if cytosolic Ca2+ ([Ca2+]i) increase through store-operated ...
Marie, Galitzine   +5 more
openaire   +2 more sources

Toward the roles of store-operated Ca2+ entry in skeletal muscle

Pflügers Archiv - European Journal of Physiology, 2010
Store-operated Ca(2+) entry (SOCE) has been found to be a rapidly activated robust mechanism in skeletal muscle fibres. It is conducted across the junctional membranes by stromal interacting molecule 1 (STIM1) and Orai1, which are housed in the sarcoplasmic reticulum (SR) and tubular (t-) system, respectively.
Launikonis, Bradley S.   +2 more
openaire   +5 more sources

Historical Overview of Store-Operated Ca2+ Entry

2016
Calcium influx is an essential mechanism for the activation of cellular functions both in excitable and non-excitable cells. In non-excitable cells, activation of phospholipase C by occupation of G protein-coupled receptors leads to the generation of inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), which, in turn, initiate two Ca(2+) entry ...
Letizia, Albarran   +3 more
openaire   +2 more sources

Analysis of Store-Operated Ca2+ Entry in Primary T Cells

Calcium ions (Ca2+) are key second messengers for signal transduction in virtually all cells. In T cells, Ca2+ signals are generated upon T cell receptor (TCR) stimulation in a two-step integrated process known as Store-Operated Ca2+ Entry (SOCE), which involves the depletion of endoplasmic reticulum (ER) Ca2+ stores, followed by the influx of ...
Sara T, Granados   +3 more
openaire   +2 more sources

Regulatory mechanisms controlling store-operated calcium entry

Frontiers in Physiology, 2023
Darren Boehning, Askar Akimzhanov
exaly  

Store-Operated Calcium Entry and Its Implications in Cancer Stem Cells

Cells, 2022
José Sánchez-Collado   +2 more
exaly  

Store-Operated Calcium Entry in Skeletal Muscle: What Makes It Different?

Cells, 2021
Maud Frieden   +2 more
exaly  

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