Results 21 to 30 of about 135,944 (267)

Study of the protective efficacy of CombiMab-2 against human immunodeficiency virus type 1 in mice humanised with CD4⁺ T-lymphocytes

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Despite existing treatment methods, complete eradication of human immunodeficiency virus (HIV) infection remains an unattainable goal due to the high variability of HIV type 1 (HIV-1).
D. S. Leontyev, F. A. Urusov, D. V. Glazkova, B. V. Belugin, O. V. Orlova, R. R. Mintaev, G. M. Tsyganova, E. V. Bogoslovskaya, G. A. Shipulin   +8 more
doaj   +1 more source

Akkermansia muciniphila is a new universal probiotic on the basis of live human commensal gut bacteria: the reality or legend?

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Contemporary information on biology of Akkermansia muciniphila and the role of these gut mucolytic anaerobic bacteria in physiological functions, metabolic and signaling reactions in human health and diseases are presented in the review.
B. A. Shenderov, S. M. Yudin, A. V. Zagaynova, M. P. Shevyreva   +3 more
doaj   +1 more source

Barriers and Facilitators in Interorganizational Disaster Response: Identifying Examples Across Europe

International Journal of Disaster Risk Science, 2020
Disaster response actors are facing new challenges, which encompass not only new and ever more complex threats but also the need to collaborate across organizational boundaries and even state borders.
Claudia Berchtold, Maike Vollmer, Philip Sendrowski, Florian Neisser, Larissa Müller, Sonja Grigoleit   +5 more
doaj   +1 more source

Spatiotemporal Evolution and Coupling Analysis of Human Footprints and Habitat Quality: Evidence of 21 Consecutive Years in China

Land
Assessing the spatiotemporal evolution characteristics of habitat quality, human footprint, and coupling coordination between two systems in continuous cycles and on national scales is of great significance to maintaining biodiversity and sustainable ...
Qiang Xue, Lu Lu, Yang Zhang, Changbo Qin   +3 more
doaj   +1 more source

Identification and functional characteristic of SARS-CoV-2-specific T lymphocytes in COVID-19 patients up to 16 months after disease onset

Медицинская иммунология
In cases of respiratory viral infection, along with innate immunity mechanisms, the adaptive immune system plays a crucial role in the body’s defence. The efficiency of its cellular component is crucial for pathogen elimination.
I. S. Vladimirov, A. S. Zhdanova, V. E. Mukhin, V. V. Makarov, V. S. Yudin, S. A. Kraevoy   +5 more
doaj   +1 more source

A clinical case of reverse left ventricular remodeling in patient with pathogenic TTN mutation. Case report [PDF]

Терапевтический архив
Dilated cardiomyopathy (DCM) is a leading cause of heart failure, sudden cardiac death, and heart transplantation in young patients. The causes of DCM are varied and include genetic factors and metabolic, infectious, toxic and others factors. Today it is
Svetlana N. Nasonova, Aleksei N. Meshkov, Igor V. Zhirov, Yulia F. Osmolovskaya, Anastasiia A. Shoshina, Alan V. Gagloev, Irina H. Dzhumaniiazova, Elena A. Zelenova, Veronika V. Erema, Mariia S. Gusakova, Mikhail V. Ivanov, Mikhail V. Terekhov, Daria A. Kashtanova, Alexsandra I. Nekrasova, Sergey I. Mitrofanov, Andrey S. Shingaliev, Vladimir S. Yudin, Anton A. Keskinov, Nataliya V. Gomyranova, Uliana V. Chubykina, Marat V. Ezhov, Sergey N. Tereshchenko, Sergey M. Yudin, Sergey A. Boytsov   +23 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Benchmark of the Oxford Nanopore, EM-seq, and HumanMethylationEPIC BeadChip for the detection of the 5mC sites in cancer and normal samples

Frontiers in Epigenetics and Epigenomics
Introduction: Whole-genome DNA methylation identification is crucial for profiling physiologically and clinically relevant epigenetic changes. Although there are multiple experimental methods, their accuracy, advantages, and disadvantages need to be ...
Kseniia A. Deinichenko, Valentina G. Vynogradskaya, Pavel A. Grebnev, Valeriya M. Mikova, Dmitriy O. Bobylev, Abusaid M. Shaymardanov, Alexey A. Ivashechkin, Marina V. Erokhina, Alexandra I. Akinshina, Anna V. Semyanihina, Anna V. Semyanihina, Sergey I. Mitrofanov, Konstantin S. Grammatikati, Vladimir S. Yudin, Sergey M. Yudin, Antonida V. Makhotenko, Anton A. Keskinov, Sergey A. Kraevoy, Anna S. Makarova, Ekaterina A. Snigir, Dmitry V. Svetlichnyy, Veronika I. Skvortsova   +21 more
doaj   +1 more source