Results 21 to 30 of about 249,873 (317)

Stratejik Planlama Süreci Kişisel-Değerlendirme Ölçeği (SPSKDÖ): geçerlik ve güvenirlik çalışması

Spormetre Beden Eğitimi ve Spor Bilimleri Dergisi, 2015
Bu çalışma ile Stratejik Planlama Süreci Kişisel-Değerlendirme Ölçeği’nin (Strategic Planning Process Self-Assessment Questionaire-SPSAQ, Strategic Futures Consulting, Inc., 2013) geçerlik ve güvenirlik çalışmasının yapılarak, Türkçe’ye uyarlanması ...
Özgül Sema Alay, Mehmet Karakılıç, Murat Aslan   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

?????????Strategic Planning?????????

Strategic planning is a crucial management tool used by the most outstanding companies and the wealthiest countries in the world. One presents an approach that is easy to apply to any organization. The strategic management process begins with its schedule each year, followed by business intelligence gathering summarized through a SWOT-GO.
Shougang Zhang, Amily Wang Guenier
openaire   +4 more sources

Benchmark of the Oxford Nanopore, EM-seq, and HumanMethylationEPIC BeadChip for the detection of the 5mC sites in cancer and normal samples

Frontiers in Epigenetics and Epigenomics
Introduction: Whole-genome DNA methylation identification is crucial for profiling physiologically and clinically relevant epigenetic changes. Although there are multiple experimental methods, their accuracy, advantages, and disadvantages need to be ...
Kseniia A. Deinichenko, Valentina G. Vynogradskaya, Pavel A. Grebnev, Valeriya M. Mikova, Dmitriy O. Bobylev, Abusaid M. Shaymardanov, Alexey A. Ivashechkin, Marina V. Erokhina, Alexandra I. Akinshina, Anna V. Semyanihina, Anna V. Semyanihina, Sergey I. Mitrofanov, Konstantin S. Grammatikati, Vladimir S. Yudin, Sergey M. Yudin, Antonida V. Makhotenko, Anton A. Keskinov, Sergey A. Kraevoy, Anna S. Makarova, Ekaterina A. Snigir, Dmitry V. Svetlichnyy, Veronika I. Skvortsova   +21 more
doaj   +1 more source

Model of scenario development in defense planning: Integration of scenario and decision: Making methods [PDF]

Војно дело, 2017
It is almost impossible to predict the future environment today, so instead of using prediction different methods of scenario development are used. Scenario as a hypothetical situation for future environment enables exploration of different possibilities
Mitić Vlada M., Dimić Srđan H., Kankaraš Milan S.   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Optimization algorithm of power system line loss management using big data analytics

Energy Informatics
As global energy demand continues to rise and renewable energy sources develop rapidly, the operational efficiency and stability of power systems have emerged as primary challenges in energy management. Line loss within these systems is a critical factor
Yang Li, Danhong Zhang, Ming Tang
doaj   +1 more source

New pathogenic mutation in LMNA gene: Clinical case of familial cardiomyopathy

Терапевтический архив
We present a clinical case of familial LMNA-associated cardiomyopathy, confirmed by whole genome sequencing. The typical for lamin-associated cardiomyopathy indicates pathogenic nature of the mutation in the first exon of LMNA gene, previously considered
Svetlana Y. Kashtanova, Elena М. Rimskaya, Aleksei N. Meshkov, Nataliia А. Mironova, Irina K. Dzhumaniiazova, Elena A. Zelenova, Veronika V. Daniel', Mikhail V. Ivanov, Daria A. Kashtanova, Vladimir S. Yudin, Anton A. Keskinov, Sergey I. Mitrofanov, Alexsandra I. Akinshina, Yulia N. Vanyushina, Sergey А. Kraevoy, Sergey M. Yudin, Sergey P. Golitsyn   +16 more
doaj   +1 more source

Trade-Offs between Urban Green Space and Densification: Balancing Outdoor Thermal Comfort, Mobility, and Housing Demand

Urban Planning, 2021
Urban green spaces reduce elevated urban temperature through evaporative cooling and shading and are thus promoted as nature-based solutions to enhance urban climates.
Sabrina Erlwein, Stephan Pauleit
doaj   +1 more source